Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Accurate in-line protein quantification with process Raman analysis

Discover how to utilize process Raman analysis for accurate protein quantification in downstream biopharmaceutical processes.

From Thermo Fisher Scientific – Portable and Handheld Raman Spectroscopy 7 Nov 2024

Spatially resolved DLS versus conventional DLS

In this article, InProcess-LSP compares spatially resolved DLS and conventional DLS.

From InProcess-LSP 6 Nov 2024

Real-time droplet size monitoring of nano emulsions during high pressure homogenization

Nano emulsions are widespread as intermediate or end-products in food, cosmetics, pharmaceutical and chemical industries.

From InProcess-LSP 6 Nov 2024

Real-time process control in nanodispersion manufacturing via continuous nanoparticle size monitoring

In this article, InProcess demonstrates the potential of in-line nanoparticle size measurements using the NanoFlowSizer (NFS) as a PAT method.

From InProcess-LSP 6 Nov 2024

'PhaSR-DLS’: A new advancement in spatially resolved DLS for enhanced inline and off-line nanoparticle sizing

In this article, InProcess describes improved inline and off-line nanoparticle sizing techniques with spatially resolved DLS.

From InProcess-LSP 6 Nov 2024

InProcess-LSP: Providers of groundbreaking PAT for nanoparticle characterization

InProcess-LSP are a young organization, founded in 2014, they have since emerged as providers of groundbreaking process analytical technology for nanoparticle characterization. This article provides a brief background to the company and their products.

From InProcess-LSP 6 Nov 2024

Lipid-based nanoparticles: Manufacturing and inline size characterization

Lipid-based nanoparticles have emerged as highly useful particles in the pharmaceutical industry. However, their manufacturing involves complex processes and in-process monitoring, such as inline size characterization, is becoming more and more important.

From InProcess-LSP 6 Nov 2024

How do results from different dynamic light scattering instruments compare?

Dynamic Light Scattering is commonly used to rapidly measure the hydrodynamic size and size dispersity of nanoparticles in suspension. Several commercial DLS instruments exist, using a range of illumination wavelengths and detection angles.

From InProcess-LSP 6 Nov 2024

How can you measure particle size CQAs in (sterile) pharmaceutical packaging? – non-invasive measurements using SR-DLS

This article explores how you can measure particle size CQAs in (sterile) pharmaceutical packaging, and discusses non-invasive measurements using SR-DLS.

From InProcess-LSP 6 Nov 2024

Continuous processing and enhanced control of lipid-based nanoparticles: LNPs and liposomes

Nanoparticles have once again reached the spotlight, this time as a critical tool to combat the spread of covid-19. In this particular case, messenger ribonucleic acid (mRNA) encapsulated in lipid nanoparticles (LNPs) have been successfully manufactured, distributed and administered to populations throughout the world.

From InProcess-LSP 6 Nov 2024

Continuous size monitoring of turbid titanium dioxide nanosuspensions with the Nanoflowsizer

This article details how the nanoflowsizer is used for continuous size monitoring of turbid titanium dioxide nanosuspensions.

From InProcess-LSP 6 Nov 2024

Continuous manufacturing of liposomal products

This article discusses continuous manufacturing and the increasing interest of this over traditional batch processing for nanoparticle drug delivery systems.

From InProcess-LSP 6 Nov 2024

Continuous inline size monitoring of low turbidity suspensions under flow in biopharmaceutical processes

The size and size distribution of low turbidity suspensions in various (bio)pharmaceutical products, including liposomes, lipid nanoparticles, recombinant proteins, and antibodies, plays a significant role in their pharmacokinetic and pharmacodynamic profile in vivo. These factors directly influence therapeutic efficacy, immunogenicity, and safety. Consequently, particle size is considered one of the critical quality attributes for such products.

From InProcess-LSP 6 Nov 2024

Life Science White Papers

Accurate in-line protein quantification with process Raman analysis

Spatially resolved DLS versus conventional DLS

Real-time droplet size monitoring of nano emulsions during high pressure homogenization

Real-time process control in nanodispersion manufacturing via continuous nanoparticle size monitoring

'PhaSR-DLS’: A new advancement in spatially resolved DLS for enhanced inline and off-line nanoparticle sizing

InProcess-LSP: Providers of groundbreaking PAT for nanoparticle characterization

Lipid-based nanoparticles: Manufacturing and inline size characterization

How do results from different dynamic light scattering instruments compare?

How can you measure particle size CQAs in (sterile) pharmaceutical packaging? – non-invasive measurements using SR-DLS

Continuous processing and enhanced control of lipid-based nanoparticles: LNPs and liposomes

Continuous size monitoring of turbid titanium dioxide nanosuspensions with the Nanoflowsizer

Continuous manufacturing of liposomal products

Continuous inline size monitoring of low turbidity suspensions under flow in biopharmaceutical processes

A new method for non-invasive or inline detection of aggregates and oversized particles in nanosuspensions

Rapid ethylene oxide detection in Polysorbate 80 using SIFT-MS

Throughput nitrosamine analysis in drug products using SIFT-MS

The hidden costs of outdated LIMS systems

High throughput thermal stability screening of biologic drugs with RS-DSC technology

Rapid thermal stability screening of monoclonal antibody drug products with RS-DSC

Repetitive strain injuries: The hidden danger in laboratory work

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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