Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

How NMR Revealed p53's Hidden Abilities

As the most frequently altered gene in human cancers, p53 is possibly the most important gene in cancer biology. Indeed, the gene for p53 is damaged or missing in at least half of all cancers. Yet, despite its relevance to the field, we are still understanding how p53 functions, and recent research - with the help of nuclear magnetic resonance (NMR) spectroscopy - demonstrates how it continues to surprise us.

From Bruker BioSpin - NMR, EPR and Imaging 2 Oct 2015

Measuring Silver Distribution in Wound Dressings

The occurrence of bacterial infection occurring with certain kinds of wounds can be minimized by using wound dressings containing silver.

From Thermo Fisher Scientific – X-Ray Photoelectron Spectroscopy (XPS) 24 Sep 2015

Surface Characterization of Disposable Laboratory Gloves

Disposable elastic gloves are widely used in scientific laboratories and in many industries for the handling of critical surfaces.

From Thermo Fisher Scientific – X-Ray Photoelectron Spectroscopy (XPS) 24 Sep 2015

Characterization of Protein Stability Using Differential Scanning Calorimetry

One of the major advantages of differential scanning calorimetry (DSC) is that it depends on heat measurements, which make characterization of native biomolecules possible.

From Malvern Panalytical 14 Sep 2015

Characterizing Exosomes and Microvesicles with Nanoparticle Tracking Analysis

To arrive at the particle size distribution of samples in a liquid suspension, nanoparticle tracking analysis (NTA) uses the characteristics of both Brownian motion and light scattering. A laser beam is transmitted via a sample chamber and the suspended particles in the beam path disperse light in such a way that is possible to observe clearly using a camera-mounted 20x magnification microscope.

From Malvern Panalytical 14 Sep 2015

Chromatrap® - Rapid, Consistent, High-Throughput ChIP-seq Assay for Protein-DNA Analysis

One of the major tasks in present-day biology is to map the chromosomal positions of nucleosomes, TFs, chromatin remodeling enzymes, histone modifications, polymerases and chaperones. Genome-wide profiling of histone alterations and DNA-binding proteins is performed using a method called chromatin immunoprecipitation followed by sequencing or ChIP-seq.

From Chromatrap® - Porvair Sciences Ltd 9 Sep 2015

Top Tips for Handheld Pipetting

Best pipetting practices are key to producing optimal results. Pipetting errors occur when common technique mistakes are made that lead to discrepancies.

From INTEGRA Biosciences 3 Sep 2015

Using Dynamic Light Scattering Technique to Measure the Size of Submicron Liposomes

This article looks at the use of dynamic light scattering technique to measure the size of submicron liposomes.

From Entegris, Inc. 27 Aug 2015

Samsung Medical Center Installs ABB’s PCS100 AVCs to Protect Cancer Treatment Machines from Voltage Fluctuations

Korean-based company, Samsung Medical Center (SMC) has installed four PCS100 active voltage conditioners (AVCs) at its facility. The installation process was successfully carried out by the Power Electronics team at ABB.

From ABB Limited 17 Aug 2015

Using Taylor Dispersion Analysis for Evaluating the Self-Association Behavior of Insulin with Concentration

Taylor dispersion analysis, also referred to as TDA, is an orthogonal method used for stability and sizing analyses of biomolecules in solution. Research has shown that hydrodynamic radius (Rh) measurements obtained from TDA on monoclonal antibodies (mAbs) and other mono-disperse, unstressed protein-based systems are analogous to data acquired using dynamic light scattering (DLS), a well-known, complementary method.

From Malvern Panalytical 30 Jul 2015

Relative Viscosity Screening of Monoclonal Antibody Formulations at Low Concentrations and Low Viscosities

The biopharmaceutical industry faces a continuous pressure to deliver innovative treatments in a safe and appropriate manner, including the rapidly growing area of therapeutic antibodies.

From Malvern Panalytical 30 Jul 2015

Using Taylor Dispersion Analysis to Evaluate Stability and Self-Association of Insulin Under Different Formulation Conditions

Taylor dispersion analysis (TDA) is an orthogonal method for stability and sizing analyses of biomolecules in solution. Previous research has shown that hydrodynamic radius (Rh) measurements from TDA on monoclonal antibodies (mAbs) and other monodisperse systems are similar to data acquired using dynamic light scattering (DLS), a well-known, complementary method.

From Malvern Panalytical 30 Jul 2015

Using Nuclear Magnetic Resonance Spectroscopy for In Situ Analysis of Natural Samples

Nuclear magnetic resonance (NMR) spectroscopy is a powerful research technique that exploits the magnetic characteristics of certain atomic nuclei. It is used to elucidate structure and understand molecular interactions and serves as a useful tool in environmental studies.

From Bruker BioSpin - NMR, EPR and Imaging 23 Jul 2015

Understanding the Antioxidant Properties of Coffee

As one of the most popular and widely consumed drinks, coffee has long been a staple of breakfast tables and cafes worldwide. But, more recently, research has begun to reveal the benefits of coffee that go beyond a pick-me-up and could have a genuine impact on our health.

From Bruker BioSpin - NMR, EPR and Imaging 20 Jul 2015

Revealing the Chemical Composition of e-Cigarettes

Following the rapid rise in popularity of e-cigarettes, nuclear magnetic resonance (NMR) spectroscopy could help policymakers grappling with regulation.

From Bruker BioSpin - NMR, EPR and Imaging 6 Jul 2015

VUmc, Xenics TeamUp in Thermography Project for Clinical Research Programs

Xenics is a Europe-based company specializing in the development and manufacture of next-generation infrared cameras, imagers, and customized imaging systems that range from the LWIR to the visible spectrum. The company has teamed up with the VU University Medical Center (VUmc) of Amsterdam, The Netherlands, for the development of ground-breaking clinical research programs.

From Xenics 6 Jul 2015

Life Science White Papers

How NMR Revealed p53's Hidden Abilities

Measuring Silver Distribution in Wound Dressings

Surface Characterization of Disposable Laboratory Gloves

Characterization of Protein Stability Using Differential Scanning Calorimetry

Characterizing Exosomes and Microvesicles with Nanoparticle Tracking Analysis

Chromatrap® - Rapid, Consistent, High-Throughput ChIP-seq Assay for Protein-DNA Analysis

Top Tips for Handheld Pipetting

Using Dynamic Light Scattering Technique to Measure the Size of Submicron Liposomes

Samsung Medical Center Installs ABB’s PCS100 AVCs to Protect Cancer Treatment Machines from Voltage Fluctuations

Using Taylor Dispersion Analysis for Evaluating the Self-Association Behavior of Insulin with Concentration

Relative Viscosity Screening of Monoclonal Antibody Formulations at Low Concentrations and Low Viscosities

Using Taylor Dispersion Analysis to Evaluate Stability and Self-Association of Insulin Under Different Formulation Conditions

Using Nuclear Magnetic Resonance Spectroscopy for In Situ Analysis of Natural Samples

Understanding the Antioxidant Properties of Coffee

Revealing the Chemical Composition of e-Cigarettes

VUmc, Xenics TeamUp in Thermography Project for Clinical Research Programs

Using the SPECTROstar Nano for Testing Free Amino Nitrogen Content in Alcoholic Beverages

Quality Control of Distilled Spirits and Beer Using SPECTROstar Nano

Using IP-One HTRF® Assay to Identify Low Affinity Compounds

Microplate Readers for HTRF Measurements

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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