Immune System News and Research

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Expansion of intermediate cells in prostate cancer correlates with treatment resistance and poor outcomes

Researchers have characterised prostate cancer cell dynamics at a single-cell resolution across the timespan of the disease – from its beginning to the point of androgen independence, where the tumour no longer responds to hormone deprivation therapy.

14 Dec 2022

Study uncovers a new immune culprit in Alzheimer’s disease

The reason your three-pound brain doesn't feel heavy is because it floats in a reservoir of cerebrospinal fluid (CSF), which flows in and around your brain and spinal cord.

13 Dec 2022

Vitamin D supplements reduce the risk of dynapenia in older people by 78%

Vitamin D plays an important role in the regulation of calcium and phosphorus absorption by the organism.

13 Dec 2022

Strong connection between inflammatory bowel disease and periodontitis

Inflammatory bowel disease often coexists with periodontal disease. This is shown by new publications from a European research project that explored the connection between the two diseases.

13 Dec 2022

'Cellular glue' opens the door to building tissues and organs

Researchers at UC San Francisco have engineered molecules that act like "cellular glue," allowing them to direct in precise fashion how cells bond with each other.

13 Dec 2022

Nanomaterial can indirectly affect the immune system via the gut microbiome, study shows

The nanomaterial graphene oxide-;which is used in everything from electronics to sensors for biomolecules-;can indirectly affect the immune system via the gut microbiome, as shown in a new study on zebrafish by researchers at Karolinska Institutet in Sweden.

12 Dec 2022

Antibody discovery could explain why so many group A strep vaccines have failed

Researchers at Lund University in Sweden have discovered an antibody with the potential to protect against Strep A infection, as well as a rare form of antibody binding, that leads to an effective immune response against bacteria.

12 Dec 2022

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

A patient with relapsed T cell leukemia has been given base-edited T-cells in a world-first use of a base-edited cell therapy, in a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

12 Dec 2022

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

A new therapy that makes the immune system kill bone marrow cancer cells was successful in as many as 73 percent of patients in two clinical trials, according to researchers from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.

12 Dec 2022

Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

Patients taking efgartigimod, a drug being studied for use to treat chronic primary immune thrombocytopenia (ITP), exhibited a significantly greater improvement in platelet counts which are essential to clotting and stopping bleeding, compared to those taking a placebo, according to results reported from the ADVANCE IV clinical trial, which was conducted globally, including at Georgetown University Medical Center.

12 Dec 2022

How vaping impacts alveolar macrophage lipid content

The use of e-cigs increases the risk of acute respiratory syndrome.

11 Dec 2022

An epigenetic modification improves the defense against infections, research shows

During infections, the hematopoietic system switches from normal to emergency mode. This improves the defense against the pathogens.

9 Dec 2022

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma.

9 Dec 2022

UH researchers investigate how traumatic experiences affect mental and physical health of migrants

In a first of its kind study, University of Houston psychology researchers are investigating how the trauma experienced by migrants before and during the journey to the United States affects their mental and physical health.

8 Dec 2022

Multi-stage HIV vaccine regimen shows promising results in Phase 1 clinical trial

The George Washington University Vaccine Research Unit in partnership with Scripps Research, IAVI, Fred Hutchinson Cancer Center (FHCC) and the National Institutes of Health, National Institute of Allergy and Infectious Diseases Vaccine Research Center published the results of their Phase 1 Clinical Trial in Science.

8 Dec 2022

Immune System News and Research

Expansion of intermediate cells in prostate cancer correlates with treatment resistance and poor outcomes

Study uncovers a new immune culprit in Alzheimer’s disease

Vitamin D supplements reduce the risk of dynapenia in older people by 78%

Strong connection between inflammatory bowel disease and periodontitis

'Cellular glue' opens the door to building tissues and organs

Nanomaterial can indirectly affect the immune system via the gut microbiome, study shows

Antibody discovery could explain why so many group A strep vaccines have failed

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

Study shows potential benefits of efgartigimod as a treatment for immune thrombocytopenia

How vaping impacts alveolar macrophage lipid content

An epigenetic modification improves the defense against infections, research shows

Study shows how an inflammatory molecule causes life-threatening airway damage in asthma patients

UH researchers investigate how traumatic experiences affect mental and physical health of migrants

Multi-stage HIV vaccine regimen shows promising results in Phase 1 clinical trial

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

Study explores the risk of new-onset diabetes mellitus following SARS-CoV-2 infections

Cancer immunotherapies can become more potent depending on the time of day

Air pollution-triggered immune surveillance deficits in the lungs increase the risk of respiratory diseases with aging

Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

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