Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Pilot clinical trial tests new treatment for type 1 diabetes

Type 1 diabetes is a chronic condition in which the body's own immune system attacks and destroys beta cells in the pancreas. Once the beta cells are destroyed, the pancreas can no longer produce insulin. Currently, there is no cure for T1D and treatment focuses on managing blood sugar levels.

6 Dec 2019

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Patients with nonalcoholic steatohepatitis, a chronic liver disease and a leading cause for liver transplantation in the U.S., currently lack an approved drug therapy, but this may soon change.

6 Dec 2019

Time-restricted eating can help treat metabolic syndrome

Metabolic syndrome affects nearly 30 percent of the U.S. population, and increases the risk for type 2 diabetes, heart disease and stroke. But lifestyle interventions such as adopting a healthy diet and increasing physical exercise are difficult to maintain and, even when combined with medication, are often insufficient to fully manage the disease.

5 Dec 2019

More research funding needed to improve pancreatic cancer survival rates

Pancreatic cancer is the third deadliest form of the disease after lung cancer and colorectal cancer.

4 Dec 2019

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different stages of the disease. However, this technique provides only two-dimensional images of the liver tissue in low resolution and overlooks potentially important 3D structural changes.

4 Dec 2019

Experimental drug better for repeat kidney cancer patients than FDA-approved equivalent

Kidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression with an experimental drug called tivozanib compared to an alternative approved by the U.S. Food and Drug Administration, according to a City of Hope-led study.

4 Dec 2019

1 in 5 adolescents have prediabetes in U.S.

The recent report by the U.S. Centers for Disease Control and Prevention (CDC) published in JAMA Pediatrics, highlights the rising prevalence of prediabetes, which can lead to type 2 diabetes if it’s not treated or controlled early. In the country, an estimated 18 percent among adolescents between the ages of 12 and 18, and 24 percent among young adults, between 19 and 34 have prediabetes.

3 Dec 2019

UIC researchers receive $2.9 million to study sleep apnea and chronic kidney disease

University of Illinois at Chicago researchers received $2.9 million from the National Institute of Diabetes and Digestive and Kidney Diseases to study the outcomes of patients with sleep apnea and chronic kidney disease.

3 Dec 2019

Early-morning, starch-rich meal improves glycemic control among type 2 diabetics

Type 2 diabetics inject themselves with insulin, a hormone that regulates the movement of sugar into liver, muscle and fat cells, up to four times a day. But insulin injections are linked to weight gain and the loss of control of blood sugar levels. This triggers a vicious cycle of higher insulin doses, continuous weight gain, a higher incidence of cardiovascular disease and other complications.

3 Dec 2019

Virome analysis reveals clues for increased risk of type 1 diabetes in children

New results from The Environmental Determinants of Diabetes in the Young study show an association between prolonged enterovirus infection and the development of autoimmunity to the insulin-producing pancreatic beta-cells that precedes type 1 diabetes.

2 Dec 2019

Hops compounds may combat metabolic syndrome by changing the gut microbiome

Compounds from hops may combat metabolic syndrome by changing the gut microbiome and altering the metabolism of acids produced in the liver, new research at Oregon State University suggests.

26 Nov 2019

Diabetes curriculum may help empower students to make healthy choices

For Lola McPherren, learning about diabetes is personal. The Juanita High School ninth-grader had a grandfather with diabetes. She recalled that he gave himself a shot of insulin before a meal, and that he also never really changed his diet to help control the disease. He died in February.

25 Nov 2019

Obese teenagers at risk for brain damage, suggests new study

A new study being presented at the yearly conference of the Radiological Society of North America (RSNA) reports that MRI scanning of the brain shows signs of brain damage in obese adolescents – and that these signs could be the result of brain inflammation.

25 Nov 2019

MRI reveals signs of brain damage among obese adolescents

Biomedical imaging of obese adolescents' brains has revealed signs of damage that may be related to inflammation.

25 Nov 2019

Study: Low-calorie sweeteners cause only modest weight changes and metabolic effects

New research suggests that low-calorie sweeteners cause only modest changes in blood sugar, insulin levels, insulin sensitivity and weight gain, as compared to those induced by sugar. The study is published ahead of print in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology.

22 Nov 2019

Insulin News and Research

Further Reading

Pilot clinical trial tests new treatment for type 1 diabetes

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Time-restricted eating can help treat metabolic syndrome

More research funding needed to improve pancreatic cancer survival rates

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

Experimental drug better for repeat kidney cancer patients than FDA-approved equivalent

1 in 5 adolescents have prediabetes in U.S.

UIC researchers receive $2.9 million to study sleep apnea and chronic kidney disease

Early-morning, starch-rich meal improves glycemic control among type 2 diabetics

Virome analysis reveals clues for increased risk of type 1 diabetes in children

Hops compounds may combat metabolic syndrome by changing the gut microbiome

Diabetes curriculum may help empower students to make healthy choices

Obese teenagers at risk for brain damage, suggests new study

MRI reveals signs of brain damage among obese adolescents

Study: Low-calorie sweeteners cause only modest weight changes and metabolic effects

Recently discovered protein may play key role in obesity and metabolic disease

Leg cramps could be a sign of peripheral artery disease

In this Democratic debate, health care issues took a backseat

Prior DDT exposure may contribute to diabetes risk among Asian Indian immigrants

Prior exposure to pollutants linked to increased risk of diabetes in Indian immigrants

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