Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Porvair Sciences releases 2015 catalogue of tissue culture plastics and epigenetic consumables

Porvair Sciences has released a new 2015 catalogue that describes its popular range of high quality tissue culture treated plastics and consumable products for Epigenetics.

From Chromatrap® - Porvair Sciences Ltd 22 Dec 2014

UTSA, UTHSCSA researchers to jointly develop next-generation breast cancer treatment drugs

Stanton McHardy, associate professor of chemistry and director of the Center for Innovative Drug Discovery in The University of Texas at San Antonio College of Sciences, is partnering on a $1.9 million award to develop next-generation breast cancer treatment drugs.

19 Dec 2014

Penn, UGA scientists awarded new contract to develop genome database for microbial pathogens

At the turn of the millennium, the cost to sequence a single human genome exceeded $50 million, and the process took a decade to complete. Microbes have genomes, too, and the first reference genome for a malaria parasite was completed in 2002 at a cost of roughly $15 million. But today researchers can sequence a genome in a single afternoon for just a few thousand dollars. Related technologies make it possible to capture information about all genes in the genome, in all tissues, from multiple individuals.

18 Dec 2014

Pharmacology 2014 to showcase latest research on NHS care

The British Pharmacological Society has announced that its annual meeting, Pharmacology 2014, will showcase the latest research on the NHS care received by children and the elderly in the UK. New findings in these 'Cinderella' areas (so-called because they are often neglected or over-looked) represent just a small sample of the cutting-edge research being presented next week.

14 Dec 2014

UB study creates new awareness for diabetics who are at risk for dehydration

Some drugs used to treat diabetes mimic the behavior of a hormone that a University at Buffalo psychologist has learned controls fluid intake in subjects. The finding creates new awareness for diabetics who, by the nature of their disease, are already at risk for dehydration.

12 Dec 2014

Scientists to explore effectiveness of tadalafil drug to tackle vascular dementia

Scientists are to explore whether drugs usually used to treat erectile problems by expanding blood vessels could become the next major way to tackle the dementia epidemic.

11 Dec 2014

STSI researchers launch study to examine root cause of sudden unexpected death

Researchers at the Scripps Translational Science Institute have launched a clinical trial aimed at cracking one of the toughest mysteries in forensic science -- sudden unexplained death.

11 Dec 2014

iTeos Therapeutics, Pfizer form strategic collaboration for cancer immunotherapeutics

iTeos Therapeutics SA announced today a strategic collaboration with Pfizer Inc. pursuant to which iTeos will license to Pfizer rights to iTeos' pre-clinical compounds targeting Indoleamine 2,3-dioxygenase (IDO1) and Tryptophan 2,3-dioxygenase (TDO2). Pfizer will be responsible for the development and commercialization of IDO1 and TDO2 drug candidates.

8 Dec 2014

Study provides insights into genetic underpinnings of childhood epilepsies

Technological advances in genetic analysis have uncovered changes in single genes that account for a surprising number of infantile and early-childhood epilepsies. Though some of the affected genes have been identified, the physical manifestations of these alterations remain largely uncharacterized.

7 Dec 2014

Scientists devise powerful algorithm to improve effectiveness of research technology harnessing RNAi

Scientists at Cold Spring Harbor Laboratory have devised a powerful algorithm that improves the effectiveness of an important research technology harnessing RNA interference, or RNAi.

7 Dec 2014

Isis Pharmaceuticals CEO honored with SCRIP Lifetime Achievement Award

Stanley T. Crooke, Ph.D., M.D., founder, CEO and chairman of the board of directors of Isis Pharmaceuticals, Inc., has been awarded the 2014 SCRIP Lifetime Achievement Award, one of the most prestigious of its kind in the pharmaceutical and biotechnology industries worldwide.

5 Dec 2014

Pharmacyclics wins 2014 Society for Medicines Research Award for Drug Discovery

Pharmacyclics, Inc. today announced that it has won the prestigious 2014 Society for Medicines Research Award for Drug Discovery for its discovery of ibrutinib (IMBRUVICA). The award was presented by The Society of Medicines Research at its biennial award lecture in Kensington, London.

4 Dec 2014

Cytation™ 5 Cell Imaging Multi-Mode Reader to be introduced by BioTek at ASCB 2014

Join BioTek Instruments as they introduce the Cytation™ 5 Cell Imaging Multi-Mode Reader at the ASCB 2014 Conference and Exhibition to be held December 6-10 in Philadelphia, Pennsylvania. BioTek’s “Think Possible” philosophy is reflected in their microplate-based imaging, detection, liquid handling and automation solutions and the company will showcase their newest innovations at Booth #349.

3 Dec 2014

Human stem cells made from adult donor cells remember their origin, say McMaster scientists

Scientists at McMaster University have discovered that human stem cells made from adult donor cells "remember" where they came from and that's what they prefer to become again.

3 Dec 2014

SAFit-ligands provide foundation for novel treatment of stress-related psychiatric disorders

The FK506-binding protein 51 (FKBP51) is an established risk factor for stress-related psychiatric disorders such as major depression. Drug discovery for FKBP51 has been hampered by the inability to pharmacologically differentiate against the very similar functional counterplayer FKBP52.

3 Dec 2014

Monash University, 60P Australia partner to develop Fenretinide drug for dengue fever

Monash University and 60P Australia Pty Ltd, a subsidiary of 60° Pharmaceuticals LLC, have announced today an exclusive partnering deal, with 60P obtaining rights to develop the drug Fenretinide for dengue fever.

2 Dec 2014

Otsuka Pharmaceutical to acquire Avanir Pharmaceuticals for $3.5B

Avanir Pharmaceuticals, Inc. today announced that it has entered into a definitive agreement with Otsuka Pharmaceutical Co., Ltd. pursuant to which Otsuka will acquire Avanir for $17.00 per share in cash.

2 Dec 2014

U of T professor wins GSK's 2014 Discovery Fast Track Challenge devoted for cancer research

University of Toronto (U of T) Professor Tania Watts is a winner of GSK's 2014 Discovery Fast Track Challenge, which is designed to accelerate the translation of academic research into novel therapies.

2 Dec 2014

Sanford-Burnham, Mayo Clinic scientists to jointly find new treatment for resistant hypertension

Sanford-Burnham Medical Research Institute at Lake Nona and Mayo Clinic today announced that a joint team of scientists has been selected as a winner of GlaxoSmithKline's 2014 Discovery Fast Track Challenge.

2 Dec 2014

Apitope's ATX-F8-117 granted orphan medicinal product designation for treatment of haemophilia A

Apitope, the drug discovery and development company focused on disease-modifying treatments for patients with autoimmune and allergic diseases, announced today that the European Medicines Agency Committee for Orphan Medicinal Products has granted orphan medicinal product designation to ATX-F8-117 for the treatment of haemophilia A.

25 Nov 2014

Drug Discovery News and Research

Further Reading

Porvair Sciences releases 2015 catalogue of tissue culture plastics and epigenetic consumables

UTSA, UTHSCSA researchers to jointly develop next-generation breast cancer treatment drugs

Penn, UGA scientists awarded new contract to develop genome database for microbial pathogens

Pharmacology 2014 to showcase latest research on NHS care

UB study creates new awareness for diabetics who are at risk for dehydration

Scientists to explore effectiveness of tadalafil drug to tackle vascular dementia

STSI researchers launch study to examine root cause of sudden unexpected death

iTeos Therapeutics, Pfizer form strategic collaboration for cancer immunotherapeutics

Study provides insights into genetic underpinnings of childhood epilepsies

Scientists devise powerful algorithm to improve effectiveness of research technology harnessing RNAi

Isis Pharmaceuticals CEO honored with SCRIP Lifetime Achievement Award

Pharmacyclics wins 2014 Society for Medicines Research Award for Drug Discovery

Cytation™ 5 Cell Imaging Multi-Mode Reader to be introduced by BioTek at ASCB 2014

Human stem cells made from adult donor cells remember their origin, say McMaster scientists

SAFit-ligands provide foundation for novel treatment of stress-related psychiatric disorders

Monash University, 60P Australia partner to develop Fenretinide drug for dengue fever

Otsuka Pharmaceutical to acquire Avanir Pharmaceuticals for $3.5B

U of T professor wins GSK's 2014 Discovery Fast Track Challenge devoted for cancer research

Sanford-Burnham, Mayo Clinic scientists to jointly find new treatment for resistant hypertension

Apitope's ATX-F8-117 granted orphan medicinal product designation for treatment of haemophilia A

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