Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

A-PARADDISE consortium obtains funds to develop innovative therapies for neglected parasitic diseases

The international consortium A-PARADDISE (Anti-Parasitic Drug Discovery in Epigenetics), coordinated by Inserm, has just obtained funds of €6 million from the European Commission to conduct large-scale testing of innovative therapies against four neglected parasitic diseases: schistosomiasis, leishmaniasis, Chagas disease and malaria.

4 Mar 2014

BioTek wins Extraordinary New Product Line award for Cytation 3 Cell Imaging Multi-Mode Reader

BioTek Instruments, Inc., received Thermo Fisher Scientific's "Extraordinary New Product Line" award for their Cytation 3 Cell Imaging Multi-Mode Reader. The award was presented at the Fisher Scientific North America Sales Meeting, held February 24-26, 2014 in Denver, Colorado. Cytation 3 was recognized by Fisher Scientific's product management team for its innovative technology and successful sales performance.

4 Mar 2014

Researchers identify mutations in gene that can reduce risk of developing type 2 diabetes

An international team led by researchers at the Broad Institute and Massachusetts General Hospital (MGH) has identified mutations in a gene that can reduce the risk of developing type 2 diabetes, even in people who have risk factors such as obesity and old age.

3 Mar 2014

UCLA develops experimental treatment that eliminates acute type of leukemia in mice

A diverse team of scientists from UCLA's Jonsson Comprehensive Cancer Center has developed an experimental treatment that eradicates an acute type of leukemia in mice without any detectable toxic side effects.

28 Feb 2014

Sarepta Therapeutics reports non-GAAP net loss of $29.1 million for Q4 2013

Sarepta Therapeutics, Inc., a developer of innovative RNA-based therapeutics, today reported financial results for the three months and year ended December 31, 2013, and provided an update of recent corporate developments.

27 Feb 2014

Protein M: an interview with Rajesh Grover, PhD, senior staff scientist, Lerner laboratory, TSRI

Protein M is a cell surface protein from Mycoplasma Genitalium that binds to all human antibodies.

26 Feb 2014

UCLA scientists developed experimental treatment that eradicates acute type of leukemia in mice

A diverse team of scientists from UCLA's Jonsson Comprehensive Cancer Center have developed an experimental treatment that eradicates an acute type of leukemia in mice without any detectable toxic side effects. The drug works by blocking two important metabolic pathways that the leukemia cells need to grow and spread.

25 Feb 2014

IRSF announces new research grants for translational research program and clinical trials

The International Rett Syndrome Foundation (IRSF) announces today ten (10) new research grants at leading global research institutions; a new Translational Research Program; and additional funding for current human clinical trials.

24 Feb 2014

NCI recommends renewal for Wistar's Support Grant with award of $14.9M

After an extensive review by a panel of top cancer experts, the National Cancer Institute (NCI) rated The Wistar Institute Cancer Center as "exceptional" and recommended renewal for Wistar's Support Grant with an award of $14.9 million over the next five years.

24 Feb 2014

Researcher uses computational approach to speed up process of drug discovery

OIST researcher uses a computational approach in identifying proteins that will interact with potential drugs to speed up the process of drug discovery.

24 Feb 2014

Jubilant Biosys expands drug discovery alliance with Janssen Pharmaceutica

Jubilant Biosys, a Bengaluru based subsidiary of Jubilant Life Sciences, announced today that it has expanded its drug discovery alliance with Janssen Pharmaceutica N.V., Beerse, Belgium.

20 Feb 2014

GENFIT receives FDA Fast Track designation for GFT505 development program in NASH

GENFIT, a biopharmaceutical company at the forefront of drug discovery and development, focusing on the early diagnosis and preventive treatment of cardiometabolic and associated disorders, today announces that the Food and Drug Administration has granted Fast Track designation to the GFT505 development program in NASH, with effect from February 14, 2014.

18 Feb 2014

Horizon Discovery, Sirion Biotech ink supply and distribution agreement

Horizon Discovery, a leading provider of research tools to support translational genomics and the development of personalized medicines, today announced it has signed a supply and distribution agreement with Sirion Biotech GmbH.

17 Feb 2014

Scientists discover novel antibody-based therapy that targets progression of kidney fibrosis

Scientists from the University of Sheffield have developed a novel antibody-based therapy which targets the progression of life threating kidney fibrosis.

16 Feb 2014

Bioanalytical Systems revenue increases 7.2% in first quarter of fiscal 2014

Bioanalytical Systems, Inc. today announced financial results for the first quarter of fiscal 2014.

13 Feb 2014

Drive for novel antibiotics against gram-negative bacteria

Over 30 European universities, research institutes, and companies, led by GlaxoSmithKline and Uppsala University, are joining forces in a 6 year programme supported by the Innovative Medicines Initiative (IMI) to develop novel antibiotics against Gram-negative pathogens.

13 Feb 2014

EKF Molecular Diagnostics to exhibit PointMan DNA-enrichment technology at Tri-Con 2014

EKF, announces that its subsidiary company EKF Molecular Diagnostics is exhibiting its ground-breaking PointMan DNA-enrichment tech.

From EKF Diagnostics 11 Feb 2014

Domain Therapeutics, XOMA to jointly evaluate DTect-All to identify allosteric modulator antibodies

Domain Therapeutics, a biopharmaceutical company specializing in the research and development of new drug candidates targeting G protein-coupled receptors (GPCRs), today announces it has entered into a multi-step collaboration with XOMA Corporation, a leader in the discovery and development of therapeutic antibodies.

4 Feb 2014

Thermo Fisher Scientific acquires Life Technologies

Thermo Fisher Scientific, the world leader in serving science, today announced that it has completed its acquisition of Life Technologies Corporation (NASDAQ: LIFE) for $76.13 ($76.1311786) in cash per fully diluted common share, or approximately $13.6 billion, plus the assumption of $1.5 billion in net debt. The completion of the transaction follows the receipt of all required regulatory approvals.

4 Feb 2014

Selcia, University of Edinburgh collaborate to develop novel treatments for sleeping sickness

An initiative is under way to develop new drugs for a devastating tropical disease that threatens almost 70 million people in Africa.

4 Feb 2014

Drug Discovery News and Research

Further Reading

A-PARADDISE consortium obtains funds to develop innovative therapies for neglected parasitic diseases

BioTek wins Extraordinary New Product Line award for Cytation 3 Cell Imaging Multi-Mode Reader

Researchers identify mutations in gene that can reduce risk of developing type 2 diabetes

UCLA develops experimental treatment that eliminates acute type of leukemia in mice

Sarepta Therapeutics reports non-GAAP net loss of $29.1 million for Q4 2013

Protein M: an interview with Rajesh Grover, PhD, senior staff scientist, Lerner laboratory, TSRI

UCLA scientists developed experimental treatment that eradicates acute type of leukemia in mice

IRSF announces new research grants for translational research program and clinical trials

NCI recommends renewal for Wistar's Support Grant with award of $14.9M

Researcher uses computational approach to speed up process of drug discovery

Jubilant Biosys expands drug discovery alliance with Janssen Pharmaceutica

GENFIT receives FDA Fast Track designation for GFT505 development program in NASH

Horizon Discovery, Sirion Biotech ink supply and distribution agreement

Scientists discover novel antibody-based therapy that targets progression of kidney fibrosis

Bioanalytical Systems revenue increases 7.2% in first quarter of fiscal 2014

Drive for novel antibiotics against gram-negative bacteria

EKF Molecular Diagnostics to exhibit PointMan DNA-enrichment technology at Tri-Con 2014

Domain Therapeutics, XOMA to jointly evaluate DTect-All to identify allosteric modulator antibodies

Thermo Fisher Scientific acquires Life Technologies

Selcia, University of Edinburgh collaborate to develop novel treatments for sleeping sickness

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