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New biomarker of glucocorticoid action could help clinicians to tailor treatments

Researchers have uncovered pathways involved in the body's response to glucocorticoid treatments and identified a novel biomarker that could be used to monitor how these drugs work in patients, according to a clinical study published today in eLife.

6 Apr 2021

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Scientists from the Genomic Integrity and Structural Biology Group led by Rafael Fernández-Leiro at the Spanish National Cancer Research Centre have discovered how certain proteins ensure the repair of errors introduced into the DNA during its replication.

6 Apr 2021

Study lists five facts to know about antihistamines

If you are one of the millions of people worldwide suffering from allergies, you may take an antihistamine pill to ward off hives, sneezing and watery eyes.

6 Apr 2021

Implantable sensor based on gold nanoparticles revolutionizes medical diagnostics

The idea of implantable sensors that continuously transmit information on vital values and concentrations of substances or drugs in the body has fascinated physicians and scientists for a long time. Such sensors enable the constant monitoring of disease progression and therapeutic success.

6 Apr 2021

Phase 1 clinical study of unique vaccine to protect against COVID-19 begins

A unique vaccine to protect against COVID-19 begins clinical testing Tuesday, 6 April, at the Walter Reed Army Institute of Research (WRAIR), part of the U.S. Army Medical Research and Development Command.

5 Apr 2021

Genome analysis of more than 53,000 people offers valuable insights into dangerous diseases

A new analysis of the entire genetic makeup of more than 53,000 people offers a bonanza of valuable insights into heart, lung, blood and sleep disorders, paving the way for new and better ways to treat and prevent some of the most common causes of disability and death.

5 Apr 2021

Research provides insights on why redheads exhibit altered sensitivity to pain

New research led by investigators at Massachusetts General Hospital provides insights on why people with red hair exhibit altered sensitivity to certain kinds of pain. The findings are published in Science Advances.

2 Apr 2021

Study identifies new cardiometabolic factors linked to SARS-CoV-2 infection

As the COVID-19 pandemic lingers, researchers have found associations between certain lifestyle factors and a person's risk of getting infected.

1 Apr 2021

Stem cell transplants offer long-term benefits for pediatric cancer patients receiving immunotherapy

Children and young adults who receive CAR T-cell therapy for the most common childhood cancer - acute lymphoblastic leukemia - suffer remarkably fewer relapses and are far more likely to survive when the treatment is paired with a subsequent stem cell transplant, a new study finds.

1 Apr 2021

Specific gene may play a causal role in heart disease independent of cholesterol levels

High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke.

1 Apr 2021

COVID-19 vaccine acceptance in pregnancy

A new preprint research paper posted to the medRxiv* server shows that while pregnant women are seriously worried about their risk of contracting the infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but are also hesitant to take the vaccine.

1 Apr 2021

Giving chemotherapy in the morning can extend survival of glioblastoma patients

An aggressive type of brain cancer, glioblastoma has no cure. Patients survive an average of 15 months after diagnosis, with fewer than 10% of patients surviving longer than five years.

31 Mar 2021

CDC and NIH launch community COVID-19 testing initiative

The Centers for Disease Control and Prevention, in collaboration with the National Institutes of Health, has launched an innovative community health initiative called "Say Yes! COVID Test" starting in Pitt County, North Carolina, and coming soon to Chattanooga/Hamilton County Tennessee.

31 Mar 2021

SwRI researchers part of two collaborative teams receive SAMF bioscience grants

Collaborative teams that include Southwest Research Institute staff received two of six recently awarded San Antonio Medical Foundation (SAMF) bioscience grants. SwRI, in collaboration with UT Health San Antonio and University Health System, received a nearly $200,000 grant to develop machine learning algorithms for cancer detection.

31 Mar 2021

New Phase 1 clinical trial of investigational vaccine against B.1.351 SARS-CoV-2 variant begins

An investigational vaccine designed to protect against the B.1.351 SARS-CoV-2 variant has been administered as part of a new Phase 1 clinical trial evaluating the vaccine candidate's safety and immunogenicity in adult volunteers.

31 Mar 2021

Scientists discover how Streptococcus pyogenes can obtain nutrition from the skin surface

Streptococcus pyogenes is one of the most important bacterial causes of human skin infections. If S. pyogenes invades deep into the tissue, it can cause life-threatening illnesses, such as sepsis and toxic shock.

31 Mar 2021

Early treatment with anti-VEGF injections slows diabetic retinopathy

Early treatment with anti-VEGF injections slowed diabetic retinopathy in a clinical study from the DRCR Retina Network (DRCR.net). However, two years into the four-year study its effect on vision was similar to standard treatment, which usually begins at the onset of late disease.

31 Mar 2021

Widely available drug reduces morbidity, mortality in COVID-19-infected mice

Mount Sinai researchers have found that a widely available and inexpensive drug targeting inflammatory genes has reduced morbidity and mortality in mice infected with SARS-CoV-2, the virus that causes COVID-19.

31 Mar 2021

COVID-19 patients with dementia have higher risk for complications, mortality

Early in the pandemic, neurologists expressed concern that COVID-19 patients with dementia may be at higher risk for complications and mortality.

31 Mar 2021

COVID-19 associated seizures may increase death risk in patients

COVID-19 can have damaging effects on multiple organs in the body, including the brain. A new study led by investigators at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center (BIDMC) indicates that some hospitalized patients with COVID-19 experience non-convulsive seizures, which may put them at a higher risk of dying. The findings are published in the Annals of Neurology.

31 Mar 2021

Medical Research News and Research

New biomarker of glucocorticoid action could help clinicians to tailor treatments

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Study lists five facts to know about antihistamines

Implantable sensor based on gold nanoparticles revolutionizes medical diagnostics

Phase 1 clinical study of unique vaccine to protect against COVID-19 begins

Genome analysis of more than 53,000 people offers valuable insights into dangerous diseases

Research provides insights on why redheads exhibit altered sensitivity to pain

Study identifies new cardiometabolic factors linked to SARS-CoV-2 infection

Stem cell transplants offer long-term benefits for pediatric cancer patients receiving immunotherapy

Specific gene may play a causal role in heart disease independent of cholesterol levels

COVID-19 vaccine acceptance in pregnancy

Giving chemotherapy in the morning can extend survival of glioblastoma patients

CDC and NIH launch community COVID-19 testing initiative

SwRI researchers part of two collaborative teams receive SAMF bioscience grants

New Phase 1 clinical trial of investigational vaccine against B.1.351 SARS-CoV-2 variant begins

Scientists discover how Streptococcus pyogenes can obtain nutrition from the skin surface

Early treatment with anti-VEGF injections slows diabetic retinopathy

Widely available drug reduces morbidity, mortality in COVID-19-infected mice

COVID-19 patients with dementia have higher risk for complications, mortality

COVID-19 associated seizures may increase death risk in patients

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