Immune System News and Research

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A digital twin for your immune system

In a recent study posted to the NPJ Digital Medicine journal, researchers illustrated a framework for constructing digital twins of the human immune system.

23 May 2022

BNT162b2 vaccine induces robust SARS-CoV-2 immunity in children

In a recent study posted to the medRxiv* pre-print server, researchers evaluated coronavirus disease 2019 (COVID-19) vaccine-induced humoral immune response in five to 11-year-old children.

23 May 2022

Novel genetic test enables earlier, more accurate diagnosis of primary immunodeficiency disorders

Primary immunodeficiency disorders (PID) can result in chronic and sometimes life-threatening infections. More than 450 PIDs have been described, but timely and accurate diagnoses remain a challenge.

23 May 2022

UVA scientists make progress in their longstanding efforts to combat tuberculosis

As headlines focus on COVID-19 and, now, monkeypox, tuberculosis remains one of the great scourges of infectious disease around the world. Approximately 1.5 million people died of tuberculosis in 2020, the World Health Organization reports.

23 May 2022

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

A new study investigated whether a specific population of local Bmem cells in the proximal LNs produce secondary GC responses that are different from those at distal sites and if the location in humoral immunity is relevant only to nonlymphoid tissues.

23 May 2022

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

Researchers observed SARS-CoV-2 downregulates the expression of MHC class I molecules.

23 May 2022

New ‘Labskin Microbiome Friendly+ Seal of Approval’ unveiled

Labskin, a division of DeepVerge has today announced that it is setting an exacting standard for the skincare industry, the ‘Labskin Microbiome Friendly+ Seal of Approval.’

23 May 2022

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Scientists from St. Jude Children's Research Hospital have shown that the innate immune sensor, ZBP1, and its associated inflammatory cell death pathway, PANoptosis, are major contributors to the negative effects of interferon treatment and high interferon levels in some COVID-19 patients.

20 May 2022

ANU research could lead to better treatment options for rare, deadly bacterial infection

New research from The Australian National University could lead to better treatment options for a rare but very lethal type of bacterial infection.

20 May 2022

Researchers analyze the development and genetic profile of brain's immune cells

Thanks to over a century of modern neuroscience, we have made significant strides in our understanding of the brain. Nonetheless, we have only just begun to scratch the surface of how this amazingly complex organ works.

20 May 2022

Researchers discover how one type of T cell creates functionally distinct, but genetically identical daughter cells

Scientists at St. Jude Children's Research Hospital have solved an immunology puzzle. A CD8+ T cell can have two functionally distinct daughter cells after it divides, despite the cells being genetically identical.

20 May 2022

Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

A blood-based tumor biomarker can predict the benefit of immunotherapy to patients with non-small cell lung cancer, according to a study published in Nature Medicine.

20 May 2022

Study explores if prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism

The authors of the current study looked at the potential for an increased risk of parkinsonism following a bout of SARS-CoV-2 infection through accepted post-viral mechanisms.

20 May 2022

Probiotic supplements accelerate the maturation of microbiome in extremely preterm infants

University of Calgary researchers have shown probiotic supplements can help form a healthy microbiome in the gut of the tiniest infants who are born without a fully formed gut microbiome.

20 May 2022

A step-by-step plan to create a digital twin of the human immune system

An article published May 20 in Nature Digital Medicine provides a step-by-step plan for an international effort to create a digital twin of the human immune system.

20 May 2022

The enigma of post-acute infection syndromes

In a recent review published in the journal Nature Medicine, researchers summarized known literature findings of the unexplained post-acute infection syndromes (PAISs).

20 May 2022

Studies provide insight into how long COVID-19 immunity lasts and nature of immune recall

How does the immune system remember and recognize viral invaders it has encountered in the past? A trio of newly published studies of people infected with SARS-CoV-2, vaccinated against the virus or both, are providing tantalizing new clues about the factors that influence the speed and magnitude of the immune system's response to subsequent infection with variants of SARS-CoV-2.

19 May 2022

Researchers discover possible connection between harmful amyloid production and COVID-19 symptoms

In patients with serious and long-term COVID-19, disturbed blood coagulation has often been observed. Now, researchers at Linköping University, Sweden, have discovered that the body's immune system can affect the spike protein on the surface of the SARS-CoV-2 virus, leading to the production of a misfolded spike protein called amyloid.

19 May 2022

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

In studies with mouse and human tissue, as well as live mice, Johns Hopkins Medicine researchers report that a snag in the normal process of cleaning up broken DNA in brain cells may hasten the progression of Parkinson's disease.

19 May 2022

Mice study links dietary cholesterol with exacerbation of influenza

New research from the University of Illinois suggests high levels of dietary cholesterol make mice sicker when infected with influenza. The study is the first to link cholesterol in the diet with exacerbation of a viral infection.

19 May 2022

Immune System News and Research

A digital twin for your immune system

BNT162b2 vaccine induces robust SARS-CoV-2 immunity in children

Novel genetic test enables earlier, more accurate diagnosis of primary immunodeficiency disorders

UVA scientists make progress in their longstanding efforts to combat tuberculosis

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

New ‘Labskin Microbiome Friendly+ Seal of Approval’ unveiled

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

ANU research could lead to better treatment options for rare, deadly bacterial infection

Researchers analyze the development and genetic profile of brain's immune cells

Researchers discover how one type of T cell creates functionally distinct, but genetically identical daughter cells

Blood-based biomarker can predict the benefit of immunotherapy to lung cancer patients

Study explores if prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism

Probiotic supplements accelerate the maturation of microbiome in extremely preterm infants

A step-by-step plan to create a digital twin of the human immune system

The enigma of post-acute infection syndromes

Studies provide insight into how long COVID-19 immunity lasts and nature of immune recall

Researchers discover possible connection between harmful amyloid production and COVID-19 symptoms

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

Mice study links dietary cholesterol with exacerbation of influenza

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