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New approach to destroy HIV reservoirs

Current HIV treatments need to be taken for life by those infected as antiretroviral therapy is unable to eliminate viral reservoirs lurking in immune cells. Institut Pasteur scientists have identified the characteristics of CD4 T lymphocytes that are preferentially infected by the virus - it is their metabolic (or energy-producing) activity1 that enables the virus to multiply.

21 Dec 2018

GW researchers receive NIH funding to study causes of high risk of heart disease in HIV patients

Atherosclerosis and cardiovascular disease are major complications of HIV infection and cannot currently be treated by antiretroviral treatments.

21 Dec 2018

Three studies examine readiness of U.S. emergency departments to care for children

Three papers from research teams led by a Massachusetts General Hospital physician examine the current readiness of U.S. emergency departments to care for children and describe an initiative that led to the appointment of a Pediatric Emergency Care Coordinator - a step considered the single best intervention to improve pediatric emergency care - in all Massachusetts EDs.

20 Dec 2018

Study identifies late-Gen X and early-Gen Y as age cohorts with elevated mortality patterns

Declining life expectancies in the U.S. include Gen X and Y Americans, in addition to the older Baby Boomers. But the causes of premature mortality vary by race, gender and ethnicity, according to a new study from Duke University.

20 Dec 2018

Tau protein reduces neural activity in Alzheimer's mouse models

A study from Massachusetts General Hospital investigators sheds new light on how the hallmarks of Alzheimer's disease - amyloid-beta (A-beta) plaques and neurofibrillary tangles containing the protein tau - produce their damaging effects in the brain.

19 Dec 2018

Hep C and drug abuse often go hand in hand, but screening for infection lags

When people seek help at a drug treatment center for an opioid addiction, concerns about having contracted hepatitis C are generally low on their list.

19 Dec 2018

Pregnant women and extremely obese people at high risk of flu complications

Pregnant women and the extremely obese are among those at high risk for complications from the flu - including death - and should be tested and begin antiviral treatment promptly if they are sick enough to be hospitalized with flu symptoms, according to updated guidelines released by the Infectious Diseases Society of America.

19 Dec 2018

SLU researcher aims to eliminate TB with focus on high-risk patients

In a recent paper published in PLOS One, Soumya Chatterjee, M.D., assistant professor of infectious diseases, allergy and immunology at Saint Louis University, presents data to show that a focus on high-risk tuberculosis patients may be the answer to stalled progress in stamping out the illness in the United States.

19 Dec 2018

Study reveals how ASV and HIV-1 share similar structural features that drive membrane targeting, assembly

A key step in retroviral growth inside a cell, as described by Jamil Saad, Ph.D., and colleagues, is portrayed on the cover of The Journal of Biological Chemistry.

18 Dec 2018

Study finds epigenetic differences in the brains of individuals with schizophrenia

A study using a PET scan tracer developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital has identified, for the first time, epigenetic differences between the brains of individuals with schizophrenia and those of unaffected study participants.

17 Dec 2018

Experimental HIV vaccine strategy works in non-human primates, research shows

For more than 20 years, scientists at Scripps Research have chipped away at the challenges of designing an HIV vaccine. Now new research, published in Immunity, shows that their experimental vaccine strategy works in non-human primates.

14 Dec 2018

Podcast: KHN’s ‘What the Health?’ Insurance enrollment is lagging — and there are lots of reasons why

With less than a week to go before the deadline in most states, enrollment in health insurance for 2019 under the Affordable Care Act is lagging compared with the pace of previous years. That was expected, given last year's tax law eliminated the tax penalty for not having coverage starting Jan. 1. But analysts say there are other reasons for the downturn as well.

14 Dec 2018

Research: Myths about migration and health not supported by available evidence

Research published in The Lancet on 5 December revealed that harmful and unfounded myths about migration and health have become accepted and that these are used to justify policies of exclusion.

13 Dec 2018

Schistosomiasis prevention and treatment could help control HIV

Of the 34 million people worldwide with HIV, and the 200 million with schistosomiasis, the majority live in Africa— where millions of people are simultaneously infected with both diseases.

13 Dec 2018

Study finds drug targets for Ebola, Dengue, and Zika viruses

No drugs are currently available to treat Ebola, Dengue, or Zika viruses, which infect millions of people every year and result in severe illness, birth defects, and even death. New research from the Gladstone Institutes and UC San Francisco may finally change that. Scientists identified key ways the three viruses hijack the body's cells, and they found at least one potential drug that can disrupt this process in human cells.

13 Dec 2018

New ingestible capsule can be controlled using Bluetooth wireless technology

Researchers at MIT, Draper, and Brigham and Women's Hospital have designed an ingestible capsule that can be controlled using Bluetooth wireless technology. The capsule, which can be customized to deliver drugs, sense environmental conditions, or both, can reside in the stomach for at least a month, transmitting information and responding to instructions from a user's smartphone.

13 Dec 2018

New model could cure the potential to underestimate how quickly diseases spread

Researchers from the New York University Tandon School of Engineering and Politecnico di Torino, Italy, have developed a mathematical model that could cure the potential to underestimate how quickly diseases spread.

13 Dec 2018

New mouse model shows potential for rapid identification of promising muscular dystrophy therapies

A Massachusetts General Hospital research team has created a new mouse model of a common form of muscular dystrophy with the potential of rapidly distinguishing promising therapeutic drugs from those unlikely to be successful.

13 Dec 2018

NIH offers support for HIV care and prevention research in the southern United States

The National Institute of Allergy and Infectious Diseases will fund a series of collaborations with medical research institutions in the southern United States to test new ways of implementing HIV treatment and prevention tools in counties with some of the highest rates of new HIV cases nationwide.

12 Dec 2018

Sex work criminalization linked to incidences of violence finds study

A large new study has shown that sex work criminalization is associated with increased incidences of violence against them. Since most of the sex workers are unable to screen their potential clients and resort to obscure and hidden places, they are more vulnerable to crimes against them, finds the study.

11 Dec 2018

HIV News and Research

New approach to destroy HIV reservoirs

GW researchers receive NIH funding to study causes of high risk of heart disease in HIV patients

Three studies examine readiness of U.S. emergency departments to care for children

Study identifies late-Gen X and early-Gen Y as age cohorts with elevated mortality patterns

Tau protein reduces neural activity in Alzheimer's mouse models

Hep C and drug abuse often go hand in hand, but screening for infection lags

Pregnant women and extremely obese people at high risk of flu complications

SLU researcher aims to eliminate TB with focus on high-risk patients

Study reveals how ASV and HIV-1 share similar structural features that drive membrane targeting, assembly

Study finds epigenetic differences in the brains of individuals with schizophrenia

Experimental HIV vaccine strategy works in non-human primates, research shows

Podcast: KHN’s ‘What the Health?’ Insurance enrollment is lagging — and there are lots of reasons why

Research: Myths about migration and health not supported by available evidence

Schistosomiasis prevention and treatment could help control HIV

Study finds drug targets for Ebola, Dengue, and Zika viruses

New ingestible capsule can be controlled using Bluetooth wireless technology

New model could cure the potential to underestimate how quickly diseases spread

New mouse model shows potential for rapid identification of promising muscular dystrophy therapies

NIH offers support for HIV care and prevention research in the southern United States

Sex work criminalization linked to incidences of violence finds study

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