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New computer model can predict how fast enzymes work

Drug molecules and biofuels can be made to order by living cell factories, where biological enzymes do the job. Now researchers at Chalmers University of Technology have developed a computer model that can predict how fast enzymes work, making it possible to find the most efficient living factories, as well as to study difficult diseases.

2 Sep 2022

First update of living systematic review provides a comprehensive summary of studies on the risk of experiencing long COVID

Researchers presented findings from the second version of a living systematic review on long COVID.

2 Sep 2022

Horizontal gene transfer plays an essential role in keeping microbiomes healthy

Biomedical engineers at Duke University have demonstrated a microbial community phenomenon that essentially equates to teaching neighbors how to complete necessary tasks by ripping out and sharing parts of the brain.

2 Sep 2022

Study opens a window of opportunity to design RAF1 degraders against lung adenocarcinomas

One of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes -genes that cause cancer when mutated - are responsible for a quarter of all human cancers, including the three tumor types with the highest mortality rates: lung adenocarcinoma, colorectal carcinoma and pancreatic ductal adenocarcinoma.

1 Sep 2022

Dolutegravir-based regimen more effective for treating pregnant people with HIV-1

Dolutegravir-based antiretroviral therapies (ART) for HIV-1 are more effective for pregnant people than some other ART regimens commonly used in the U.S. and Europe, according to a study led by Harvard T.H. Chan School of Public Health researchers.

1 Sep 2022

New study suggests metformin is associated with less severe COVID-19 across prediabetic individuals

In a new study, researchers illustrated that metformin was associated with decreased coronavirus disease 2019 (COVID-19) severity among prediabetic patients.

1 Sep 2022

Cell Counting Without Slides to Reduce Waste and Cost

Until recently, cells were typically counted on a reusable quartz hemocytometer.

From DeNovix Inc. 1 Sep 2022

dsDNA Quantification for NGS Quality Control

Andrew Jones discusses the importance of quality control in NGS and the effect that a poorly followed protocol can have on experimental results.

From DeNovix Inc. 1 Sep 2022

Analysis of the seasonality of common human coronaviruses

A new study published in the Emerging Infectious Diseases journal aimed to analyze the circulation of four common HCoVs from July 2014 to November 2021 in the US.

31 Aug 2022

The most recent evidence about phylogenesis, pathogenesis, prevention, and treatment for monkeypox

A new review sheds light on the origins of this virus and recently acquired knowledge about its disease mechanism and the preventive and therapeutic measures appropriate in this situation.

31 Aug 2022

Moffitt study uses computer modeling to demonstrate the impact of skin homeostasis on driver and passenger mutations

All normal human tissues acquire mutations over time. Some of these mutations may be driver mutations that promote the development of cancer through increased proliferation and survival, while other mutations may be neutral passenger mutations that have no impact on cancer development.

30 Aug 2022

Research provides a major step forward to growing human kidney in a dish

Kidney disease affects one in nine adults globally and the incidence of kidney failure is steadily rising around the world.

30 Aug 2022

Italian study finds SARS-CoV-2 in clinical samples collected before December 2019

Researchers discuss the association of SARS-CoV-2 with morbilliform skin rash and confirms viral circulation in September 2019.

30 Aug 2022

New treatment may be effective in addressing the long-term effects of preeclampsia

Preeclampsia is a condition that affects the placenta during pregnancy and is dangerous for both the fetus and the mother.

30 Aug 2022

Researchers identify potential new pathway for treating a sporadic form of ALS

Researchers have published two papers describing how they identified a potential new pathway for treating a sporadic form of amyotrophic lateral sclerosis (ALS).

30 Aug 2022

Researchers demonstrate a pneumatic hand made using a commercial 3D printer

Artificial pneumatic muscles consisting of 3D-printed structures that can extend and contract as required: this is the innovative design of the GRACE actuators devised by researchers from the Istituto Italiano di Tecnologia (IIT, Italian Institute of Technology) in Genoa and the Scuola Superiore Sant'Anna (SSSA, Sant'Anna School of Advanced Studies) in Pisa.

30 Aug 2022

COVID-19 may provoke IgA-associated vasculitis

In a new study, scientists showed that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection provokes immunoglobulin A (IgA)-associated vasculitis (IgAV).

30 Aug 2022

Research reveals administration of ineffective COVID-19 treatments after FDA deauthorization

Monoclonal antibodies are laboratory-designed treatments tailor-made to fight specific infections. In early 2021, the U.S. Food & Drug Administration issued emergency use authorization for two monoclonal antibodies (bamlanivimab/etesevimab and casirivimab/imdevimab) for the treatment of mild to moderate COVID-19 in high-risk, non-hospitalized patients.

30 Aug 2022

Disrupting a virus’s genome packaging can halt replication, study finds

Like savvy international travelers, viruses know exactly how to pack. With the genetic instructions for the next generation folded just so, snuggled into a custom-made outer covering studded with cell-grabbing proteins, these tiny invaders quest for new digs on the reg.

30 Aug 2022

3 shots in 1: How microparticles could be used to deliver self-boosting vaccines

In this interview, we speak to Morteza Sarmadi from MIT about his labs latest research that developed microparticles able to deliver self-boosting vaccines.

30 Aug 2022

Laboratory News and Research

New computer model can predict how fast enzymes work

First update of living systematic review provides a comprehensive summary of studies on the risk of experiencing long COVID

Horizontal gene transfer plays an essential role in keeping microbiomes healthy

Study opens a window of opportunity to design RAF1 degraders against lung adenocarcinomas

Dolutegravir-based regimen more effective for treating pregnant people with HIV-1

New study suggests metformin is associated with less severe COVID-19 across prediabetic individuals

Cell Counting Without Slides to Reduce Waste and Cost

dsDNA Quantification for NGS Quality Control

Analysis of the seasonality of common human coronaviruses

The most recent evidence about phylogenesis, pathogenesis, prevention, and treatment for monkeypox

Moffitt study uses computer modeling to demonstrate the impact of skin homeostasis on driver and passenger mutations

Research provides a major step forward to growing human kidney in a dish

Italian study finds SARS-CoV-2 in clinical samples collected before December 2019

New treatment may be effective in addressing the long-term effects of preeclampsia

Researchers identify potential new pathway for treating a sporadic form of ALS

Researchers demonstrate a pneumatic hand made using a commercial 3D printer

COVID-19 may provoke IgA-associated vasculitis

Research reveals administration of ineffective COVID-19 treatments after FDA deauthorization

Disrupting a virus’s genome packaging can halt replication, study finds

3 shots in 1: How microparticles could be used to deliver self-boosting vaccines

Lab Diagnostics and Automation - Second Edition eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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