Immune System News and Research

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Immune cell betrayal makes aging mice less tolerant of cold temperatures

Human evolution has provided us a level of protection from the existential threat of cold temperature with the capacity to produce heat from fat stored in the body.

1 Sep 2021

Study shows bacille Calmette-Guérin vaccine can protect mice against lethal SARS-CoV-2 challenge

A recent US study, currently available on bioRxiv* preprint server, implies that vaccination with bacille Calmette-Guérin (BCG) can limit the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by targeting innate immune pathways and could thus be used as a platform for pinpointing early immunologic events affecting the outcome of coronavirus disease (COVID-19).

1 Sep 2021

New candidate vaccine for COVID-19 found to be efficacious in preclinical models

More than a year after the start of the COVID-19 pandemic, several vaccines have been authorized thanks to unprecedented worldwide research efforts. These first-generation vaccines bring great hope and are a mainstay in fighting the virus.

1 Sep 2021

Innovative AI and simulation tools used to reveal the inner workings of Sar-CoV-2 virus

Argonne, industry and academia collaborate to bring innovative AI and simulation tools to the COVID-19 battlefront.

1 Sep 2021

New review looks at the bottlenecks and breakthroughs in cancer immunotherapy

After over a century of development, cancer immunotherapy (CIT) has risen to become a promising approach for treating cancer. Unlike conventional methods that try to kill cancer cells directly, CIT involves modifying or stimulating the immune system's natural ability to fight the disease. So far, various CIT treatments have shown remarkable results in terms of survival rates, and many new and combination strategies are currently under study.

1 Sep 2021

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Sepsis occurs when the body works so hard to fight an infection that the over-activated immune system harms a patient's own tissues as collateral damage.

31 Aug 2021

Researchers identify biomarkers for rare, serious complication in children with COVID-19

The study focused on multisystem inflammatory syndrome in children (MIS-C), an inflammatory response involving multiple organs that can occur weeks after infection with SARS-CoV-2, the virus that causes COVID-19.

31 Aug 2021

Indoor air is an important source of exposure to harmful forever chemicals, study shows

The air we breathe in our homes, schools, and workplaces can be polluted with harmful PFAS chemicals, according to a study published today in Environmental Science & Technology Letters.

31 Aug 2021

Research highlights the importance of meninges for brain development and pathology

A new study, led by researchers at the University of Gothenburg, have generated the first comprehensive transcriptional atlas of neonatal mouse meningeal leukocytes, under normal conditions and after perinatal brain injury.

31 Aug 2021

Coronavirus buildup in the lungs is likely behind high mortality rates

A buildup of coronavirus in the lungs is likely behind the steep mortality rates seen in the pandemic, a new study finds.

31 Aug 2021

Role of glycans on the SARS-CoV-2 spike protein in human receptor interaction

A team of investigators, led by Dr. Benjamin F. Mann, from Merck, USA have published a new study on the preprint server bioRxiv*. They have used a biochemical approach to control the glycosylation profile of the S protein receptor-binding domain (RBD) and to analyze the effect of different glycosylation patterns on receptor binding.

30 Aug 2021

Computational study identifies human proteins structurally similar to SARS-CoV-2 proteins

A new study published in Scientific Reports identifies the human proteins that share structural similarities with the SARS-CoV-2 proteins.

30 Aug 2021

The impact of mild SARS-CoV-2 infection on maternal-fetal immunity

Recently, a new study published on the pre-print server bioRxiv* examined the effect that maternal asymptomatic COVID-19 had on decidual and peripheral immune cells during the later stage of pregnancy.

30 Aug 2021

Study opens up a new approach to incorporating MRI into multisite pancreatic clinical trials

Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) at Vanderbilt University Medical Center led a multisite study which has demonstrated that, when controlled and standardized, quantitative magnetic resonance imaging (MRI) of the pancreas is highly reproducible when using different MRI hardware and software at different geographic locations.

28 Aug 2021

Immune System News and Research

Immune cell betrayal makes aging mice less tolerant of cold temperatures

Study shows bacille Calmette-Guérin vaccine can protect mice against lethal SARS-CoV-2 challenge

New candidate vaccine for COVID-19 found to be efficacious in preclinical models

Innovative AI and simulation tools used to reveal the inner workings of Sar-CoV-2 virus

New review looks at the bottlenecks and breakthroughs in cancer immunotherapy

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Researchers identify biomarkers for rare, serious complication in children with COVID-19

Indoor air is an important source of exposure to harmful forever chemicals, study shows

Research highlights the importance of meninges for brain development and pathology

Coronavirus buildup in the lungs is likely behind high mortality rates

Role of glycans on the SARS-CoV-2 spike protein in human receptor interaction

Computational study identifies human proteins structurally similar to SARS-CoV-2 proteins

The impact of mild SARS-CoV-2 infection on maternal-fetal immunity

Study opens up a new approach to incorporating MRI into multisite pancreatic clinical trials

Recognizing viral genomes in quick, ‘CRISP’ ways

'Humanized' mouse model beats current approaches for finding the best organ donor

Pediatric cancer patients fare worse with COVID-19 than children without cancer

Mild maternal infections can have permanent impacts on offspring immunity

New blood test could save thousands of lives by predicting sepsis before symptoms appear

Aptamer Group and Bio-Works Technologies partner to enable improved solutions for gene therapy manufacturing

Immunology eBook

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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