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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Recognizing viral genomes in quick, ‘CRISP’ ways

Researchers from China recently reviewed the latest advancements, applications, and prospects of virus detection using CRISPR-Cas systems.

27 Aug 2021

Large analysis identifies 579 genetic locations linked to anti-social behavior and addiction

An analysis of data from 1.5 million people has identified 579 locations in the genome associated with a predisposition to different behaviors and disorders related to self-regulation, including addiction and child behavioral problems.

27 Aug 2021

Adding berzosertib to standard treatment for metastatic urothelial cancer does not extend patient survival

A Phase 2 trial led by City of Hope, a world-renowned research and treatment center for cancer and diabetes, suggests that adding the novel ataxia telangiectasia and Rad3-related (ATR) inhibitor drug berzosertib to standard-of-care chemotherapy for patients with metastatic urothelial cancer does not extend progression-free survival.

27 Aug 2021

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Genomics, proteomics, metabolomics, transcriptomics -- rapid advances in high-throughput biomedical technologies has enabled the collection of data with unprecedented detail from the growing number of omics.

27 Aug 2021

Study identifies 579 genomic regions associated with predisposition to self-regulating behaviors

Researchers have identified 579 locations in the human genome associated with a predisposition to self-regulation-related behaviors, including addiction and child behavioral problems. With data from 1.5 million people of European descent, the effort is considered to be one of the largest genome-wide association studies to date.

26 Aug 2021

Studies offer insight into how the human body develops and acquires mutations throughout life

New insights into how the human body develops from one cell into trillions, and the genetic mutations that cells pick up along the way, have been generated by two studies from scientists at the Wellcome Sanger Institute, the University of Cambridge and their collaborators.

26 Aug 2021

Research offers new insight into how to treat endometriosis

Endometriosis is a painful, chronic condition in which tissue from the uterus inappropriately grows outside the uterus.

26 Aug 2021

Study unravels widespread tumor suppression mechanism that halts cancer metastasis

According to a study by The Wistar Institute, the tumor suppressor Parkin, whose levels are reduced in different cancer types, causes acute metabolic and oxidative stress, suppresses mitochondrial trafficking, and blocks tumor cell movement, reducing primary and metastatic tumor growth.

26 Aug 2021

An existing drug may function as targeted therapy for ALL in children

A new study from Linköping University has shown that the tumour-inhibiting gene TET2 is silenced in a large fraction of cases of acute lymphoblastic leukemia (ALL) in children.

25 Aug 2021

Study uncovers epigenetic mechanisms that promote glioma tumor growth

Northwestern Medicine investigators have discovered the epigenetic mechanisms involved in the regulation of multiple oncogenes in glioma cells, mechanisms that promote overall glioma tumor growth and resistance to therapy, according to a study published in the journal Clinical Cancer Research.

25 Aug 2021

Penn study shows how certain proteins have evolved to suppress cheating chromosomes

Eggs and sperm are special cells for many reasons, but one of the characteristics that sets them apart is that, unlike other human cells, which have two copies of 23 chromosomes, one from the mother and one from the father, these sex cells, or gametes, have only one.

25 Aug 2021

Two studies on gastrointestinal stroma tumors describe advances that may lead to new treatments

Gastrointestinal stroma tumors (GIST) are cancers that start in specialized nerve cells found in the digestive system, from the esophagus and stomach to the intestines and rectum.

25 Aug 2021

Food products labeled as containing “wild mushrooms” often misleading

A team of researchers at the University of Utah and the Natural History Museum of Utah has found that wild mushroom ingredients often consist entirely or in part of cultivated species. These include the ubiquitous white and brown “button” mushrooms and portabella (Agaricus bisporus), oyster (Pleurotus spp.), and shiitake (Lentinula edodes).

24 Aug 2021

Lack of inflammatory genes makes carnivores the biggest carriers of zoonotic pathogens

Carnivorous animals lack key genes needed to detect and respond to infection by pathogens, a study has found.

24 Aug 2021

Peptoids could one day cure or prevent herpes, COVID-19

In addition to antibodies and white blood cells, the immune system deploys peptides to fight viruses and other pathogens.

24 Aug 2021

Antiviral strategy using synthetic peptoid has promising implications for fighting infection

Scientists have manufactured a synthetic form of peptide to combat viral infections, with tests already conducted on HSV-1 as well as SARS-CoV-2.

24 Aug 2021

First-in-kind kidney cancer drug developed at UTSW receives FDA approval

A first-in-kind kidney cancer drug developed from laboratory and translational studies conducted at UT Southwestern Medical Center received approval from the Food and Drug Administration, providing a new treatment for patients with familial kidney cancer.

24 Aug 2021

Pericentromeric noncoding RNA provokes inflammatory gene expression in senescence and cancer

Research from the Cancer Institute at the Japanese Foundation for Cancer Research (JFCR), which was published today (August 23, at 3 pm US ET) in the leading international scientific journal Proceedings of the National Academy of Sciences of the United States of America, reveals that noncoding RNA derived from pericentromeric repetitive sequences provokes inflammatory gene expression in senescence and cancer.

24 Aug 2021

Synthetic SARS-CoV-2 vs. SARS-CoV-2

Though vaccination efforts are underway in most countries, there are still limited options for treating COVID-19. Now, researchers at Penn State designed a new COVID-19 therapy that uses a defective synthetic version of the SARS-CoV-2 virus to interfere with the actual virus's replication.

23 Aug 2021

Rice bioengineer receives Trailblazer Award to develop technology for reprogramming immune cells

Viruses come in many forms, and Rice University bioengineer Isaac Hilton has long been fascinated by the kind that take control of cells without rewriting their genetic code.

23 Aug 2021

DNA News and Research

Further Reading

Recognizing viral genomes in quick, ‘CRISP’ ways

Large analysis identifies 579 genetic locations linked to anti-social behavior and addiction

Adding berzosertib to standard treatment for metastatic urothelial cancer does not extend patient survival

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Study identifies 579 genomic regions associated with predisposition to self-regulating behaviors

Studies offer insight into how the human body develops and acquires mutations throughout life

Research offers new insight into how to treat endometriosis

Study unravels widespread tumor suppression mechanism that halts cancer metastasis

An existing drug may function as targeted therapy for ALL in children

Study uncovers epigenetic mechanisms that promote glioma tumor growth

Penn study shows how certain proteins have evolved to suppress cheating chromosomes

Two studies on gastrointestinal stroma tumors describe advances that may lead to new treatments

Food products labeled as containing “wild mushrooms” often misleading

Lack of inflammatory genes makes carnivores the biggest carriers of zoonotic pathogens

Peptoids could one day cure or prevent herpes, COVID-19

Antiviral strategy using synthetic peptoid has promising implications for fighting infection

First-in-kind kidney cancer drug developed at UTSW receives FDA approval

Pericentromeric noncoding RNA provokes inflammatory gene expression in senescence and cancer

Synthetic SARS-CoV-2 vs. SARS-CoV-2

Rice bioengineer receives Trailblazer Award to develop technology for reprogramming immune cells

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

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