Chromatin Immunoprecipitation ChIP News and Research

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Epigenomic techniques used to fight disease

Humans differ from one another in many ways, including how they react to disease, because of their DNA blueprint, as well as the difference in the environments they face. These factors combine to make each person unique. Now a new study published in the journal Nature Protocols reports the development of a promising technology to uncover the process by which the body fights diseases in different ways.

4 Dec 2019

Researchers create new technology to help understand how the body battles diseases

Much remains unknown about diseases and the way our bodies respond to them, in part because the human genome is the complete DNA assembly that makes each person unique. A Virginia Tech professor and his team of researchers have created new technology to help in understanding how the human body battles diseases.

3 Dec 2019

Study finds molecular key to formation of mature and fully functioning T cells

In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and fully functioning T cells in the immune system.

25 Oct 2019

New Chromatrap ChIP-seq kit performs chromatin immunoprecipitation with unparalleled sensitivity

Porvair Sciences announces version 2.0 of its Chromatrap® ChIP-seq kit - developed to perform chromatin immunoprecipitation with unparalleled sensitivity.

From Chromatrap® - Porvair Sciences Ltd 3 Apr 2019

New mathematical method to map cell regulatory networks

Faster results. Lower costs. Fewer cells. A new mathematical method developed by researchers at Cincinnati Children's and New York University may soon make it much easier to conduct more of the complex data analysis needed to drive advances in the exploding field of personalized medicine.

6 Mar 2019

Porvair Sciences to improve the diagnosis and treatment of ovarian cancer

Porvair Sciences reports on its involvement in a new £2.6 million project led by Swansea University (UK) that aims to dramatically improve the diagnosis and treatment of ovarian cancer.

From Chromatrap® - Porvair Sciences Ltd 27 Feb 2019

Study: BldC protein in Streptomyces acts as ‘brake’ to control timing of sporulation

Streptomyces are soil-dwelling bacteria that produce approximately two-thirds of the antibiotics in current clinical use.

6 Feb 2019

Chromatrap partners with Covaris to offer highly scalable and simple ChIP workflow

Chromatrap has entered into a partnership with Covaris to offer a highly scalable and simple ChIP workflow enabling researchers to easily isolate protein-DNA complexes for downstream applications, such as ChIP-Seq, ChIP-qPCR, Next-generation sequencing, and Mass Spectrometry.

From Chromatrap® - Porvair Sciences Ltd 30 Jan 2019

Conducting ChIP-Seq with Low Cell Numbers

An interview with Dr. Kathyrn Cunningham at SfN 2018, providing advice on carrying out Chromatin Immunoprecipitation Sequencing (ChIP-seq) with low cell numbers.

From Active Motif 14 Jan 2019

Enhancers can be predicted through ChIP-seq technology

In genetics, an enhancer is a short region of DNA that can be bound by proteins to increase the likelihood that transcription of a particular gene will occur.

23 Dec 2018

Chromatrap buffer reagents for lysing cells offer many benefits

Porvair Sciences announce how its Chromatrap Lysis and Hypotonic buffers play a crucial role in enabling researchers to better understand biological organisms.

From Chromatrap® - Porvair Sciences Ltd 13 Dec 2018

Comprehensive analysis reveals weaknesses to target in common pediatric solid tumor

St. Jude Children's Research Hospital investigators have completed the most comprehensive analysis yet of a common pediatric solid tumor, identifying weaknesses to target and a promising precision medicine that is now in clinical trials.

23 Aug 2018

Porvair and Suzhou Tianlong Bio to develop epigenetic analysis technologies

Porvair Sciences are teaming up with Suzhou Tianlong Bio Technology Co Ltd (China), together with Swansea University and Xi'an Jiaotong University in a collaborative project entitled, "Automating & Stratification of Epigenetics in Healthcare" that is part of the Innovate UK / Jiangsu Industrial Challenge Programme.

From Chromatrap® - Porvair Sciences Ltd 15 Dec 2017

Research shows how glutamine plays role in regulating cellular differentiation programs

The 200 different types of cells in the body all start with the same DNA genome. To differentiate into families of bone cells, muscle cells, blood cells, neurons and the rest, differing gene programs have to be turned on or off.

17 Aug 2017

Native ChIP kit from Chromatrap is now compatible for mass spectrometry

Chromatrap announces that its popular Native ChIP kit is now fully compatible for mass spectrometry (MS) as a downstream process. Combining Chromatrap®’s unique solid-state ChIP technology with MS enables researchers to obtain high quality data sets for chromatin proteomic profiling and mapping of histone modification patterns.

From Chromatrap® - Porvair Sciences Ltd 7 Aug 2017

Biolegend chooses Chromatrap technology to power chromatin immunoprecipitation kits

Chromatrap® announces that BioLegend, a major US-based manufacturer and supplier of reagents and kits for biomedical research, has chosen their novel solid-state ChIP technology to power a new range of faster and more efficient chromatin immunoprecipitation kits.

From Chromatrap® - Porvair Sciences Ltd 30 Jun 2017

Chromatrap introduces new FFPE ChIP-seq assay kit for tissue samples, biopsies, and difficult to lyse samples

Chromatrap has introduced a new and improved version of it’s popular solid phase chromatin immunoprecipitation assay kit for chromatin extracted from Formalin Fixed Paraffin Embedded tissue.

From Chromatrap® - Porvair Sciences Ltd 4 May 2017

New and improved solid phase ChIP assay kit for FFPE tissues introduced by Chromatrap

Chromatrap® has introduced a new and improved version of it’s popular solid phase chromatin immunoprecipitation (ChIP) assay kit for chromatin extracted from Formalin Fixed Paraffin Embedded (FFPE) tissue.

From Chromatrap® - Porvair Sciences Ltd 4 May 2017

Chromatrap publishes new article comparing efficiency, sensitivity of native and cross-linked ChIP-seq kits

Chromatrap has published a new article that describes a detailed genome wide comparison of native and crosslinked chromatin immunoprecipitation followed by next generation sequencing (ChIP-seq) using the company's patented solid state spin column technology.

From Chromatrap® - Porvair Sciences Ltd 24 Mar 2017

How to improve your chromatin immunoprecipitation experiments

Chromatrap® has published a comprehensive Applications Compendium that includes hints and tips to improve your Chromatin Immunoprecipitation (ChIP) experiments, increase the effectiveness of your ChIP-seq library preparation and brings together its latest application notes in one informative document.

From Chromatrap® - Porvair Sciences Ltd 27 Oct 2016