Antibodies News and Research

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Novel method enables 3D imaging of human organs with micrometer precision

Researchers at Umeå University, Sweden, now demonstrate a method by which specific cell types in human organs can be studied with micrometer precision.

13 Sep 2021

Newly developed antibody may be used to treat muscular dystrophy

Northwestern Medicine scientists have developed an antibody that they believe can be used to treat muscular dystrophy, findings that were published in Science Translational Medicine.

13 Sep 2021

The comparative effectiveness of neutralizing monoclonal antibodies against SARS-CoV-2

A study investigated the comparative efficacy of neutralizing monoclonal antibodies against SARS-CoV-2.

13 Sep 2021

An oral COVID-19 vaccine induces mucosal and protective immunity

Researchers have collaborated to resolve the aforementioned problems associated with injection vaccines to create a thermostable vaccine that can be taken orally.

13 Sep 2021

Discovery of diverse sarbecovirus broadly neutralizing antibodies from SARS-CoV-2 “infected-vaccinated” humans

Scientists were inspired by the robust serum nAb responses in people who recovered from natural SARS-CoV-2 infection and were later vaccinated using mRNA vaccine. They isolated and characterized bnAbs from two COVID-19 convalescent donors who were recently vaccinated. These isolated bnAbs were found to be highly potent against sarbecoviruses. This research is available on the bioRxiv* preprint server.

13 Sep 2021

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

A recent report published in the journal Cell Discovery has described the immunogenicity and protective efficacy of a novel coronavirus disease 2019 (COVID-19) subunit vaccine candidate. The vaccine induces robust immune responses in rodents and non-human primates and protects the animals against severe disease.

12 Sep 2021

The strengths and weaknesses of the spike protein in SARS-CoV-2 variants

The S protein has the ability to appropriate various conformations that are dependent on the formation of the receptor-binding domain (RBD) of its protomers.

12 Sep 2021

UGA research offers hope for a viable therapeutic to combat COVID-19

As COVID-19 cases continue to skyrocket across the U.S. and the world, few options are available for treating patients infected with the SARS-CoV-2.

11 Sep 2021

Brown researchers receive $4.9 million to study COVID-19 vaccine effectiveness in older adults

To address the pressing issue of diminishing immunity among older adults to COVID-19 as well to vaccines designed to protect against the virus, a $4.9 million award from the U.S. Centers for Disease Control and Prevention will fund a two-year project led by Brown University researchers and conducted by a team spanning multiple institutions.

10 Sep 2021

Convalescent plasma does not reduce risk of intubation or death for COVID-19 hospitalized patients

A major study has found that convalescent plasma does not reduce the risk of intubation or death for COVID-19 patients.

10 Sep 2021

Nanoparticles-assisted delivery of antiviral-siRNA for treatment of COVID-19

A review aimed to determine the potential of siRNA as a potential COVID-19 treatment by reviewing the currently available literature.

10 Sep 2021

No evidence of pre-existing antibody and B cell immunity against SARS-CoV-2 in unexposed adults

A group of researchers analyzed the B cell response to SARS-CoV-2 in unexposed individuals.

10 Sep 2021

Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model

A COVID-19 vaccine, created from a virus-like nanoparticle that displays SARS-CoV-2 spike protein RBDs, effectively protects animal model from infection.

10 Sep 2021

Enzyme appears to be a major driver of dangerous pregnancy complication

A new study by UT Southwestern scientists indicates that an enzyme called protein phosphatase 2 (PP2A) appears to be a major driver of preeclampsia, a dangerous pregnancy complication characterized by the development of high blood pressure and excess protein in the urine.

9 Sep 2021

Autoimmune antibodies strongly linked to the severity of illness in COVID-19 patients

The presence of special immune system defense molecules, called autoimmune antibodies, has been strongly tied to how poorly people fare when hospitalized with COVID-19, a new study shows.

9 Sep 2021

Novel combination therapy may prolong viral suppression in patients with HIV

A novel combination treatment may increase the ability of monoclonal antibodies to control viral infection in patients diagnosed with HIV, according to a Northwestern Medicine study published in Science Translational Medicine.

9 Sep 2021

Understanding the changing coronavirus landscape

With the emergence of new SARS-CoV-2 variants such as beta and delta, people are not only getting a refresher course on the Greek alphabet but also experiencing confusion and anxiety about what the variants mean for public health.

9 Sep 2021

Mu SARS-CoV-2 variant highly resistant to neutralization by convalescent and vaccinated sera

Researchers in Japan have warned that the Mu (B.1.621) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – appears to be highly resistant to neutralization by sera from convalescent or vaccinated individuals.

8 Sep 2021

New vaccinia-based COVID-19 vaccine candidate induces robust, durable immune responses

Researchers in Australia have developed a coronavirus disease 2019 (COVID-9) vaccine that induced robust and long-lived humoral and cellular immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in both young and aging mice.

8 Sep 2021

The role of nanobodies in capturing and containing SARS-CoV-2

Scientists have repurposed the Nb Ty1 for the detection and neutralization of SARS-CoV-2.

8 Sep 2021

Antibodies News and Research

Novel method enables 3D imaging of human organs with micrometer precision

Newly developed antibody may be used to treat muscular dystrophy

The comparative effectiveness of neutralizing monoclonal antibodies against SARS-CoV-2

An oral COVID-19 vaccine induces mucosal and protective immunity

Discovery of diverse sarbecovirus broadly neutralizing antibodies from SARS-CoV-2 “infected-vaccinated” humans

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

The strengths and weaknesses of the spike protein in SARS-CoV-2 variants

UGA research offers hope for a viable therapeutic to combat COVID-19

Brown researchers receive $4.9 million to study COVID-19 vaccine effectiveness in older adults

Convalescent plasma does not reduce risk of intubation or death for COVID-19 hospitalized patients

Nanoparticles-assisted delivery of antiviral-siRNA for treatment of COVID-19

No evidence of pre-existing antibody and B cell immunity against SARS-CoV-2 in unexposed adults

Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model

Enzyme appears to be a major driver of dangerous pregnancy complication

Autoimmune antibodies strongly linked to the severity of illness in COVID-19 patients

Novel combination therapy may prolong viral suppression in patients with HIV

Understanding the changing coronavirus landscape

Mu SARS-CoV-2 variant highly resistant to neutralization by convalescent and vaccinated sera

New vaccinia-based COVID-19 vaccine candidate induces robust, durable immune responses

The role of nanobodies in capturing and containing SARS-CoV-2

A new way of characterising biomolecules eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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