Heart News and Research

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Tight glucose control lowers CVD by about 50 percent in diabetes

A significantly lower risk of heart disease can now be added to the list of proven long-term benefits of tight glucose control in people with type 1 diabetes.

12 Jun 2005

Ruboxistaurin shows favorable effects on kidney damage and function in people with type 2 diabetes and nephropathy

Eli Lilly and Company today announced encouraging results from a one-year pilot study examining the effect of ruboxistaurin mesylate in persons with type 2 diabetes and kidney disease (also known as "diabetic nephropathy").

12 Jun 2005

Rimonabant study shows significant improvements in HbA1c and cardiometabolic risk factors in people with type 2 diabetes

The reported results of a one-year phase III study in 1045 people with type 2 diabetes treated with rimonabant, the first in a new class of therapeutic agents called selective CB1 Blockers, were that rimonabant 20 mg significantly improved HbA1c (a measure of blood sugar control), dyslipidemia (abnormal levels of fat in the blood), and systolic blood pressure with a concomitant substantial reduction in abdominal obesity in people with type 2 diabetes treated with oral anti-diabetic medications and requiring further control.

12 Jun 2005

Muraglitazar lowers blood glucose and helps dyslipidemia seen in diabetes

A novel compound provides long-term lowering of blood glucose levels and improves plasma lipids (fats) that are often a problem in people with type 2 diabetes -- all in a once-daily pill, according to a report presented today at the American Diabetes Association's 65th Annual Scientific Sessions.

12 Jun 2005

Patients with newly diagnosed type 2 diabetes should be screened for retinopathy

Diabetic retinopathy has been found in nearly 8 percent of pre-diabetic participants in the Diabetes Prevention Program (DPP), according to a report presented today at the American Diabetes Association's 65th Annual Scientific Sessions.

12 Jun 2005

Researchers discover how microRNA are involved in the development of heart muscle

Researchers at UT Southwestern Medical Center have discovered how a small molecule of RNA called microRNA - a chemical cousin of DNA - helps fine tune the production of a key protein involved in the early development of heart muscle.

12 Jun 2005

Genetic variations predispose Mexican Americans to insulin resistance

Although numerous studies have shown that low-grade inflammation is linked to heart disease and diabetes, more recent studies have shown that inflammation plays a role in insulin resistance, a syndrome that leads to diabetes and heart disease and affects about one in four adults in the United States.

12 Jun 2005

Link between PKC enzyme and kidney disease in diabetes confirmed

Researchers at Joslin Diabetes Center have investigated PKC-beta - a critical enzyme implicated in the devastating complications of type 1 and type 2 diabetes - for more than two decades.

12 Jun 2005

Over-the-counter painkillers more likely to cause heart attacks than banned drug Vioxx

Researchers in the UK are saying that some of the most commonly used painkillers are more likely to cause heart attacks than Vioxx, the arthritis drug withdrawn from the market last year after it was linked to heart disease.

12 Jun 2005

Ibruprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack

Patients should not stop taking the drugs involved - non-steroidal anti-inflammatory drugs (NSAIDS) - but further investigation into these treatments is needed, say the authors.

10 Jun 2005

Ibuprofen may cause heart attacks - full disclosure of all data - including industry safety data - is essential

Speaking at the annual European conference of rheumatology, EULAR 2005, in Vienna, Austria, today (Friday 10 June 2005), Dr. Gurkirpal Singh, from Stanford University, USA, said:

10 Jun 2005

Link between hyperglycemia (high blood glucose), overexpression of PKC-beta 2 and kidney disease

Scientists at Joslin Diabetes Center have investigated PKC-beta -- a critical enzyme implicated in the devastating complications of type 1 and type 2 diabetes -- for more than two decades.

10 Jun 2005

Private health insurance given the go-ahead in Canada

A Quebec law that banned some private health insurance, has been overruled by the Supreme Court of Canada and is a decision which is likely to pave the way to a greater use of private health care to supplement a crumbling public system.

10 Jun 2005

Intensive therapy, even four years later, improves stroke victims speech

A new study suggests that when intensive therapy is used with people who suffered a stroke years earlier, their speaking ability seems to improve.

10 Jun 2005

Unique therapeutic strategy to combat cachexia

Researchers at Oregon Health & Science University's Doernbecher Children's Hospital have uncovered a unique therapeutic strategy to combat cachexia - severe malnutrition and physical wasting away - in children and adults with chronic kidney disease (CKD). The study is published in the June issue of the Journal of Clinical Investigation.

9 Jun 2005

Commonly used painkillers for treating inflammation may increase the risk of heart attack

Patients should not stop taking the drugs involved - non-steroidal anti-inflammatory drugs (NSAIDS) - but further investigation into these treatments is needed, say the authors.

9 Jun 2005

Concern for smokers who don't understand nicotine

Medical experts warned today that thousands of smokers are jeopardising their chances of quitting successfully. New data presented at the UK National Smoking Cessation Conference (UKNSCC) shows that misconceptions about the role of nicotine are preventing smokers from quitting using nicotine replacement therapies (NRT) that actually increase the chances of quitting for good.

9 Jun 2005

New start-up to market test that predicts heart attack risk

PrognostiX, a start-up company based on Cleveland Clinic technology, has received approval from the U.S. Food and Drug Administration to begin selling a diagnostic test capable of identifying patients who are in imminent danger of heart attack or death.

9 Jun 2005

US specialists call for heart patients to be screened for psychological distress

Heart patients should be screened for psychological distress and, if necessary, referred for help from mental health professionals, according to the authors of research published today (Thursday 9 June) in the European Heart Journal.

9 Jun 2005

Healthy neighborhoods for older adults subject of study

Doctors often advise their older patients to walk more to enhance their health, but what if the sidewalks are crumbling; if they don't know a neighbor who could serve as a walking partner to help them feel safe; or if there's nothing interesting to see outside of their homes?

9 Jun 2005

Heart News and Research

Tight glucose control lowers CVD by about 50 percent in diabetes

Ruboxistaurin shows favorable effects on kidney damage and function in people with type 2 diabetes and nephropathy

Rimonabant study shows significant improvements in HbA1c and cardiometabolic risk factors in people with type 2 diabetes

Muraglitazar lowers blood glucose and helps dyslipidemia seen in diabetes

Patients with newly diagnosed type 2 diabetes should be screened for retinopathy

Researchers discover how microRNA are involved in the development of heart muscle

Genetic variations predispose Mexican Americans to insulin resistance

Link between PKC enzyme and kidney disease in diabetes confirmed

Over-the-counter painkillers more likely to cause heart attacks than banned drug Vioxx

Ibruprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack

Ibuprofen may cause heart attacks - full disclosure of all data - including industry safety data - is essential

Link between hyperglycemia (high blood glucose), overexpression of PKC-beta 2 and kidney disease

Private health insurance given the go-ahead in Canada

Intensive therapy, even four years later, improves stroke victims speech

Unique therapeutic strategy to combat cachexia

Commonly used painkillers for treating inflammation may increase the risk of heart attack

Concern for smokers who don't understand nicotine

New start-up to market test that predicts heart attack risk

US specialists call for heart patients to be screened for psychological distress

Healthy neighborhoods for older adults subject of study

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