Protein News and Research

RSS

Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

First mouse model of schizophrenia

Johns Hopkins researchers have genetically engineered the first mouse that models both the anatomical and behavioral defects of schizophrenia, a complex and debilitating brain disorder that affects over 2 million Americans.

1 Aug 2007

Shutting off a critical cancer gene causes cancers in mice to self-destruct

Killing cancerous tumors isn't easy, as anyone who has suffered through chemotherapy can attest.

1 Aug 2007

Chromosomes responsible for a critical enzyme's activation during cell division

In a dividing cell, chromosomes interact with cellular scaffolding - called spindle microtubules - in order to move themselves to opposite ends of the cell, ensuring that both daughter cells receive an exact copy of their parent cell's genetic material.

1 Aug 2007

New TB vaccine could save over a million lives

Initial trials of a new tuberculosis (TB) vaccine mean the drug will now progress to phase II trials.

31 Jul 2007

Trans fats offer a double whammy

Along with the knowledge that 'trans fats' are particularly bad because they clog up arteries and increase the risk of heart attacks comes new information which makes them even more undesirable.

31 Jul 2007

Bone marrow restores fertility in female mice

A new study from Massachusetts General Hospital (MGH) researchers confirms that female mice that receive bone marrow transplantation after fertility-destroying chemotherapy can go on to have successful pregnancies throughout their normal reproductive life.

31 Jul 2007

Directed nanoparticles deliver gene therapy

After binding DNA segments to tiny iron-containing spheres called nanoparticles, researchers have used magnetic fields to direct the nanoparticles into arterial muscle cells, where the DNA could have a therapeutic effect.

31 Jul 2007

Researchers genetically modify a plant to halt reproduction of HIV related virus

In a study that could lead to new ways to prevent infection by human immunodeficiency virus (HIV) and similar organisms, Purdue University researchers have been able to genetically modify a plant to halt reproduction of a related virus.

31 Jul 2007

FOXP3 gene found to be involved in breast cancer

Researchers at the University of Michigan Comprehensive Cancer Center have identified a gene linked to the development of an aggressive form of breast cancer.

27 Jul 2007

New target for drugs to fight the HIV/AIDS virus

Researchers from Rome, Italy, describe a finding in the August 2007 print issue of The FASEB Journal that could lead to new drugs to fight the HIV/AIDS virus, as well as new vaccines to prevent infection.

27 Jul 2007

New view on role of protein synthesis in memory formation

New research from the University of Illinois challenges the premise that the brain must build new proteins in response to an experience for that experience to be recorded in long-term memory.

27 Jul 2007

Europe approves MIRCERA to treat anaemia

Roche has announced that the European Commission has approved its innovative drug MIRCERA to treat anaemia associated with chronic kidney disease (CKD).

27 Jul 2007

Scientists shed new light on how microRNAs carry out their function

MicroRNAs became the stars of the RNA universe when, in 2001, scientists found that these short RNAs can control whether or not genes are expressed.

27 Jul 2007

Researchers track how a single molecule of RNA or DNA unwinds

The process by which genes are duplicated is mysterious and complex, involving a cast of characters with diverse talents and the ability to play well with others in extremely close quarters.

27 Jul 2007

Tonsil epithelial factors may influence oropharyngeal HIV transmission

Current research demonstrates that the tonsils may possess the necessary factors to act as a transmission site for the spread of HIV.

27 Jul 2007

Scientits devise dimmer swith to regulate gene expression in mammal cells

Three Boston University biomedical engineers have created a genetic dimmer switch that can be used to turn on, shut off, or partially activate a gene's function. Professor James Collins, Professor Charles Cantor and doctoral candidate Tara Deans invented the switch, which can be tuned to produce large or small quantities of protein, or none at all.

27 Jul 2007

New findings on gene-transcription machinery

For some time, scientists have been tracking down the sequence of biochemical steps required to attract and assemble at the head end of a gene the molecular machinery needed to transcribe that gene to put to work the information it encodes.

26 Jul 2007

New understanding of Sly Syndrome

The scientist who discovered “Sly Syndrome” nearly four decades ago and a team of colleagues at Saint Louis University are a step closer to finding an approach to treat the rare genetic disease.

26 Jul 2007

Combination of blood pressure-lowering drugs stops loss of kidney function in rare genetic disease

A combination of two types of blood pressure-lowering drugs, an angiotensin-converting enzyme inhibitor (ACEI) plus an angiotensin-receptor blocker (ARB), added to enzyme replacement therapy (ERT) with agalsidase-beta (Fabrazyme, Genzyme Corporation, Cambridge, MA) is the first treatment shown to stop progressive loss of kidney function in patients with severe kidney involvement due to the rare genetic disorder Fabry disease, reports a study in the September Journal of the American Society of Nephrology.

26 Jul 2007