Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Listeria pathogen may be key to understanding cancer development

A research team including University of Central Florida Microbiology Professor Keith Ireton is using the bacterial pathogen Listeria Monocytogenes to understand the mechanisms of cell growth and cancer development.

29 Jun 2007

RNA molecules can orchestrate gene activity across vast portions of the human genome

Large, seemingly useless pieces of RNA - a molecule originally considered only a lowly messenger for DNA - play an important role in letting cells know where they are in the body and what they are supposed to become, researchers at Stanford University School of Medicine have discovered.

29 Jun 2007

New type of drug shows promise for chronic lymphocytic leukemia

A new type of engineered drug candidate has shown promise in treating chronic lymphocytic leukemia in both test tube and early animal tests, a new study shows.

29 Jun 2007

Link between ciliary signaling and cancer

Submarines have periscopes. Insects have antennae. And increasingly, biologists are finding that most normal vertebrate cells have cilia, small hair-like structures that protrude like antennae into the surrounding environment to detect signals that control cell growth.

29 Jun 2007

Protein ATM prevents DNA damage from persisting through generations

A protein long known to be involved in protecting a cell from genetic damage has been found to play an even more important role in protecting the cell's offspring.

29 Jun 2007

Key finding on ALS related protein

Chemists from UCLA and the University of Florence in Italy may have solved an important mystery about a protein that plays a key role in a particular form of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, a progressive, fatal neurodegenerative disorder that strikes without warning.

28 Jun 2007

Scientists discover role of ataxia telangiectasia mutated protein in DNA repair

Scientists from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Cancer Institute (NCI), and Integrative Bioinformatics Inc. have made an important discovery about the role of an enzyme called ataxia telangiectasia mutated protein (ATM) in the body's ability to repair damaged DNA.

28 Jun 2007

Discovery of gene and mechanism essential to the embryonic development of the epididymis

Human sperm cells travel up to 6 meters in their transit from testes to penis, and most of that journey occurs in the epididymis, a tightly coiled tube that primes the cells for their ultimate task: fertilization.

28 Jun 2007

Link between lung capacity, inflammation and chronic lung disease

People who have a reduced lung capacity may have a greater risk of heart attack and stroke because they show evidence of inflammation, reveals a study published online ahead of print in Thorax .

28 Jun 2007

Scientists create sheets of protein-gold arrays

In groundbreaking research, scientists have demonstrated the ability to strategically attach gold nanoparticles -- particles on the order of billionths of a meter -- to proteins so as to form sheets of protein-gold arrays.

28 Jun 2007

New model for signal transduction in cells

Among the key communication systems within a cell is the Wnt signaling pathway, which regulates embryonic development and whose deregulation can also contribute to cancer development.

28 Jun 2007

New genetic test advances detection and diagnosis of muscular dystrophy

A new genetic test targeting the most common types of muscular dystrophy--those caused by mutations in the dystrophin gene--is far quicker with greater accuracy and sensitivity than existing tests.

28 Jun 2007

New approach for tackling allergies

Allergies, like the common cold and asthma, have basically defied the best efforts of modern medicine to cure them.

28 Jun 2007

Popular antidepressants make elderly bones fragile

Two newly released studies have come out in support for the growing body of evidence that the most popular drugs used to treat depression may contribute to fragile bones in elderly people.

27 Jun 2007

Indian medicinal plant effective in blocking blood-vessel and tumor growth

Researchers at the University of Kentucky have advanced research of a natural product found in an Indian medicinal plant that has shown effectiveness in blocking blood-vessel and tumor growth.

27 Jun 2007

New genetic marker characterizes aggressiveness of cancer cells

Levels of a small non-coding RNA molecule called let-7 appear to define different stages of cancer better than some of the "classical" markers for tumor progression, researchers from the University of Chicago report in the June 25, 2007, early online edition of the Proceedings of the National Academy of Sciences.

26 Jun 2007

New understanding of cancer inhibitor topotecan

Researchers in Delft University of Technology's Kavli Institute of Nanoscience in The Netherlands have cast new light on the workings of the important cancer inhibitor topotecan.

26 Jun 2007

Chronic methamphetamine abuse linked to cardiovascular disease

The study is being published the week of June 25 in an advanced online edition of the Proceedings of the National Academy of Sciences.

26 Jun 2007

Scoliosis gene found

Physicians have recognized scoliosis, the abnormal curvature of the spine, since the time of Hippocrates, but its causes have remained a mystery -- until now. For the first time, researchers have discovered a gene that underlies the condition, which affects about 3 percent of all children.

26 Jun 2007

Protein C levels help predict severity of illness and risk of death in ICU patients

A simple laboratory test to measure protein C - a natural anti-blood-clotting substance that also reflects the level of inflammation in the body - may offer a useful new indicator of the severity of illness and risk of death among critically ill patients.

26 Jun 2007