Neurological Disease News and Research

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Gladstone scientists discover common mechanism that links neurodegeneration in young and old

Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF), identified a common mechanism in two forms of neurodegeneration that affect young adults or the elderly.

12 Apr 2017

Study identifies potential link between genes and treatment response in children with CAE

Consider two children who have childhood absence epilepsy (CAE), the most common form of pediatric epilepsy. They both take the same drug--one child sees an improvement in their seizures, but the other does not.

11 Apr 2017

Biomedical engineers develop new method for delivering drugs to specific neurons

Biomedical engineers have developed a way to deliver drugs to specific types of neurons in the brain, providing an unprecedented ability to study neurological diseases while also promising a more targeted way to treat them.

6 Apr 2017

WHO classifies stroke as neurological disease

The medical rationale for stroke being a neurological condition has always been compelling. We therefore welcome the latest decision by the Department of Statistics at the WHO to move the thematic block of cerebrovascular diseases from the circulatory diseases chapter to diseases of the nervous system," noted Prof Raad Shakir, head of the WHO Neurology Topic Advisory Group and President of the World Federation of Neurology.

6 Apr 2017

Experts to present diverse advances in neuromodulation at INS congress

Experts will present diverse advances in neuromodulation from May 27 to June 1, 2017 at the 13th World Congress of the International Neuromodulation Society in Edinburgh, Scotland.

30 Mar 2017

Common neurological diseases pose serious annual financial burden for the U.S.

The most common neurological diseases cost the United States $789 billion in 2014, and this figure is projected to grow as the elderly population doubles between 2011 and 2050, according to a new study published in the April issue of the Annals of Neurology.

30 Mar 2017

Researchers use stem cells to model different genetic scenarios that underlie neurologic disease

Researchers at Case Western Reserve University School of Medicine have successfully grown stem cells from children with a devastating neurological disease to help explain how different genetic backgrounds can cause common symptoms.

30 Mar 2017

Study identifies urinary biomarker that may help monitor progression of ALS

A study in Neurology suggests that analyzing levels of the protein p75ECD in urine samples from people with amyotrophic lateral sclerosis (ALS) may help monitor disease progression as well as determine the effectiveness of therapies.

22 Mar 2017

Breakthrough brain repair discovery could revolutionise treatment of Multiple Sclerosis

Queen's University Belfast scientists have discovered that specific cells from the immune system are key players in brain repair - a fundamental breakthrough that could revolutionise the treatment of debilitating neurological disorders such as Multiple Sclerosis.

15 Mar 2017

New humanized model enables better characterization of Alzheimer's pathology

Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.

24 Feb 2017

Pitt researcher receives NSF CAREER Award to develop improved screening method for dysphagia

Dysphagia, or swallowing disorders, affects nearly one in 25 adults, especially the elderly and those who have suffered a stroke or neurological disease, and results in approximately 150,000 hospitalizations annually.

14 Feb 2017

New drug discovered in zebrafish model of pediatric epilepsy shows promising results in clinical study

"Bench-to-bedside" describes research that has progressed from basic science in animal models that has led to therapies used in patients.

13 Feb 2017

Defective brain cells disposing toxic proteins may be linked to neurodegenerative diseases

Rutgers scientists say neurodegenerative diseases like Alzheimer's and Parkinson's may be linked to defective brain cells disposing toxic proteins that make neighboring cells sick.

10 Feb 2017

Designer compound may be effective tool for tackling tau-related disorders

In a study of mice and monkeys, National Institutes of Health funded researchers showed that they could prevent and reverse some of the brain injury caused by the toxic form of a protein called tau.

8 Feb 2017

MGH researchers develop novel approach to analyze brainwave activity during sleep

Massachusetts General Hospital investigators have developed a novel approach to analyze brainwaves during sleep, which promises to give a more detailed and accurate depiction of neurophysiological changes than provided by a traditional sleep study.

8 Feb 2017

Researchers develop new method for early prediction of crises in chronic diseases

Researchers from Universidad Politécnica de Madrid and Universidad Complutense de Madrid have developed a methodology early prediction of crises in chronic diseases, such as migraines.

1 Feb 2017

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Advanced engineering of a mini-intronic plasmid (MIP) system designed to carry a therapeutic gene can significantly enhance the expression of the transgene delivered using an adeno-associated viral (AAV) vector.

28 Jan 2017

Study shows long-term gains from hastening surgical interventions against epilepsy

There are important, long-term gains from hastening the processes around surgical interventions against epilepsy - before the disease has had too much negative impact on brain functions and patients' lives.

24 Jan 2017

AAV-based gene therapy to treat liver disorders advances into human testing

Liver-directed gene therapy delivered using adeno-associated viral (AAV) vectors to treat diseases such as hemophilia have advanced into human testing.

30 Dec 2016

Studies in non-human primates provide more predictive results in genetic causes of blindness

Many gene therapy-based approaches are in development to combat genetic and other causes of blindness and vision loss, and much can be learned about the safety and effectiveness of these promising new therapies by studying them first in non-human primates before initiating clinical trials, as shown by the results of a study published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

29 Dec 2016

Neurological Disease News and Research

Gladstone scientists discover common mechanism that links neurodegeneration in young and old

Study identifies potential link between genes and treatment response in children with CAE

Biomedical engineers develop new method for delivering drugs to specific neurons

WHO classifies stroke as neurological disease

Experts to present diverse advances in neuromodulation at INS congress

Common neurological diseases pose serious annual financial burden for the U.S.

Researchers use stem cells to model different genetic scenarios that underlie neurologic disease

Study identifies urinary biomarker that may help monitor progression of ALS

Breakthrough brain repair discovery could revolutionise treatment of Multiple Sclerosis

New humanized model enables better characterization of Alzheimer's pathology

Pitt researcher receives NSF CAREER Award to develop improved screening method for dysphagia

New drug discovered in zebrafish model of pediatric epilepsy shows promising results in clinical study

Defective brain cells disposing toxic proteins may be linked to neurodegenerative diseases

Designer compound may be effective tool for tackling tau-related disorders

MGH researchers develop novel approach to analyze brainwave activity during sleep

Researchers develop new method for early prediction of crises in chronic diseases

New MIP system for therapeutic gene delivery can enhance transgene expression using AAV vector

Study shows long-term gains from hastening surgical interventions against epilepsy

AAV-based gene therapy to treat liver disorders advances into human testing

Studies in non-human primates provide more predictive results in genetic causes of blindness

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