Immune System News and Research

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TBE patients continue to be affected by long-term problems

Impaired memory, reduced motivation, and declining motor skills. These are some of the problems that may persist several years after people contract tick-borne encephalitis, a University of Gothenburg thesis shows.

23 Feb 2021

Innate immune system overreacts in patients with severe COVID-19

In patients with severe COVID-19, the innate immune system overreacts. This overreaction may underlie the formation of blood clots (thrombi) and deterioration in oxygen saturation that affect the patients.

23 Feb 2021

After billions of dollars and dozens of wartime declarations, why are vaccines still in short supply?

The U.S. government has invested billions of dollars in manufacturing, used a wartime act dozens of times to boost supplies and yet there's still not enough covid vaccine on the way to meet demand — or even the government's own goals for national immunization.

23 Feb 2021

Study findings help explain the diversity of cancers in different Li-Fraumeni patients

The most frequently mutated gene in human cancers is called p53. Patients with Li-Fraumeni syndrome, which is a rare disorder that increases the risk of developing several types of cancer, often have an increased risk to develop cancers at early ages if they inherit p53 mutations.

23 Feb 2021

Protective COVID-19 antibodies can transfer from mothers to babies in the womb

Antibodies that guard against COVID-19 can transfer from mothers to babies while in the womb, according to a new study from Weill Cornell Medicine and NewYork-Presbyterian researchers published in the American Journal of Obstetrics and Gynecology.

23 Feb 2021

Universal strain of bacteria derived from healthy human skin can treat eczema

In a new study out of University of California San Diego School of Medicine, researchers have identified a universal strain of bacteria derived from healthy human skin that can treat the most common type of eczema, also known as atopic dermatitis.

23 Feb 2021

People with absence of natural killer cell receptor are likely to develop severe COVID-19

The course and severity of COVID-19 in individual patients are largely influenced by the interaction between the SARS-CoV-2 coronavirus and the human immune system.

23 Feb 2021

Genetic mechanism enables TB-causing bacterium to remember and rapidly respond to stress

Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers at Rice University and infectious disease experts at Rutgers New Jersey Medical School (NJMS).

22 Feb 2021

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Monoclonal antibodies are part of the therapeutic arsenal for eliminating cancer cells. Some make use of the immune system to act and belong to a class of treatment called "immunotherapies." But how do these antibodies function within the tumor? And how can we hope to improve their efficacy?

22 Feb 2021

Virus-specific cellular immunity may be essential for long-term protection against SARS-CoV-2

Researchers from China and the US recently synthesized select peptide pools of the structural and functional proteins of SARS-CoV-2, including spike (S), envelope (E), membrane (M), nucleocapsid (N), and protease (P) proteins as target antigens to assess COVID-19-specific immunity.

22 Feb 2021

WVU researchers set to identify SARS-CoV-2 variants, mitigate strain outbreaks

West Virginia University scientists knew it was coming. When health officials confirmed the first three cases of a COVID-19 variant in West Virginia late Friday (Feb. 19), they were not surprised.

22 Feb 2021

Seropositive individuals show similar antibody levels to a second mRNA vaccine dose

Seropositive individuals —people who received antibodies after COVID-19 infection — may be able to safely delay their second mRNA vaccine dose after all, according to the results of a new study.

22 Feb 2021

Current monoclonal antibodies less potent against SARS-CoV-2 variants

Researchers at the New York University Grossman School of Medicine and Biohaven Pharmaceuticals found that the REGN10933 and REGN10987 combination was 9.1-fold less potent on the B.1.351 variant, which emerged in South Africa, and 16.2-fold less potent on mink cluster 5.

22 Feb 2021

Study finds consistent neuroinflammatory response after intracerebral hemorrhage

Understanding how the immune system responds to acute brain hemorrhage could open doors to identifying treatments for this devastating disease.

22 Feb 2021

FDA issues guidance for medical product developers to address the emergence of SARS-CoV-2 variants

Today, the U.S. Food and Drug Administration issued guidances for medical product developers, specifically covering vaccines, diagnostics and therapeutics products, to address the emergence and potential future emergence of variants of SARS-CoV-2, the virus that causes COVID-19.

22 Feb 2021

Children exposed to air pollution may be at higher risk of disease in adulthood

Children exposed to air pollution, such as wildfire smoke and car exhaust, for as little as one day may be doomed to higher rates of heart disease and other ailments in adulthood, according to a new Stanford-led study.

22 Feb 2021

Study could lead to new strategies to prevent various cancers

Chronic inflammation drives the development of various cancers, including those of the skin, colon and pancreas. Investigators at Massachusetts General Hospital (MGH) who previously demonstrated high expression levels of an immune molecule called interleukin-33 (IL-33) during cancer-promoting inflammation have now uncovered the details behind the molecule's effects.

22 Feb 2021

Could an intranasal adjuvant to vaccines boost immunity against SARS-CoV-2 variants?

A research team from the University of Michigan Medical School, USA, developed a supplementary intranasal treatment to improve COVID-19 vaccine response and its effects on long-lasting immunity from other variants, such as the B.1.351 variant first found in South Africa.

22 Feb 2021

Study identifies immune profile of people with severe COVID-19

A team of researchers at Georgetown University Medical Center, USA, investigated how SARS-CoV-2 affects the immune system’s response during and after infection and contributes to the severity of COVID-19.

22 Feb 2021

High fructose diets might prevent proper functioning of peoples' immune system

New research by Swansea scientists in collaboration with researchers at the University of Bristol and the Francis Crick Institute in London has indicated that consuming a diet high in sugar fructose might prevent the proper functioning of peoples' immune systems in ways that have, until now, largely been unknown.

22 Feb 2021

Immune System News and Research

TBE patients continue to be affected by long-term problems

Innate immune system overreacts in patients with severe COVID-19

After billions of dollars and dozens of wartime declarations, why are vaccines still in short supply?

Study findings help explain the diversity of cancers in different Li-Fraumeni patients

Protective COVID-19 antibodies can transfer from mothers to babies in the womb

Universal strain of bacteria derived from healthy human skin can treat eczema

People with absence of natural killer cell receptor are likely to develop severe COVID-19

Genetic mechanism enables TB-causing bacterium to remember and rapidly respond to stress

In vivo imaging reveals how anti-CD20 antibodies guide the immune system to attack tumors

Virus-specific cellular immunity may be essential for long-term protection against SARS-CoV-2

WVU researchers set to identify SARS-CoV-2 variants, mitigate strain outbreaks

Seropositive individuals show similar antibody levels to a second mRNA vaccine dose

Current monoclonal antibodies less potent against SARS-CoV-2 variants

Study finds consistent neuroinflammatory response after intracerebral hemorrhage

FDA issues guidance for medical product developers to address the emergence of SARS-CoV-2 variants

Children exposed to air pollution may be at higher risk of disease in adulthood

Study could lead to new strategies to prevent various cancers

Could an intranasal adjuvant to vaccines boost immunity against SARS-CoV-2 variants?

Study identifies immune profile of people with severe COVID-19

High fructose diets might prevent proper functioning of peoples' immune system

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