Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

New insights into how obesity, type 2 diabetes can create stress response in the brain

Joslin researchers have gained new insights into how obesity and type 2 diabetes can create a stress response in the brain, especially in the hypothalamus (the brain region that regulates appetite and energy production), that may contribute to altering metabolism throughout the body. The findings are reported in the October issue of the Journal of Clinical Investigation.

2 Oct 2013

Insulin interaction map could lead to new therapeutic targets for type 2 diabetes

A team led by scientists at The Scripps Research Institute has created the first comprehensive roadmap of the protein interactions that enable cells in the pancreas to produce, store and secrete the hormone insulin. The finding makes possible a deeper scientific understanding of the insulin secretion process—and how it fails in insulin disorders such as type 2 diabetes.

1 Oct 2013

Study shows direct causative link between obesity and risk of pancreatic cancer in mice

Researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC) have found that mice made obese by being given high-calorie, high-fat diets (HFCD) developed abnormally high numbers of lesions known as pancreatic intraepithelial neoplasias (PanINs), which are known to be precursors to pancreas cancer.

1 Oct 2013

Roadmap of protein interactions may lead to new therapeutic approaches for type 2 diabetes

A team led by scientists at The Scripps Research Institute (TSRI) has created the first comprehensive roadmap of the protein interactions that enable cells in the pancreas to produce, store and secrete the hormone insulin.

1 Oct 2013

Diabetes puts you at increased risk of flu-related complications

There are certain groups of people who are at risk of serious flu complications each year, including those with diabetes.

30 Sep 2013

Diabetic patients at greater risk of breast, colon cancer

Diabetes is linked to an increased risk of developing cancer, and now researchers have performed a unique meta-analysis that excludes all other causes of death and found that diabetic patients not only have an increased risk of developing breast and colon cancer but an even higher risk of dying from them.

30 Sep 2013

Study provides new insights into type 1 diabetes pathology

Joslin researchers have identified immune cells that promote growth of beta cells in type 1 diabetes. This study provides further evidence of a changed role for immune cells in type 1 diabetes pathology. The study appears online today and will also appear in the January issue of Diabetes.

29 Sep 2013

JDRF applauds FDA approval of Medtronic's MiniMed 530G with Enlite system for T1D

JDRF, the leading global organization funding type 1 diabetes research, today applauded the U.S. Food and Drug Administration for its commitment to ensuring patients in the United States can access insulin pumps that can temporarily stop insulin delivery once sensor glucose levels fall below a predetermined threshold.

From Medtronic 29 Sep 2013

Study on tempol impacted gut bacteria may lead to new treatments for obesity

A drug that appears to target specific intestinal bacteria in the guts of mice may create a chain reaction that could eventually lead to new treatments for obesity and diabetes in humans, according to a team of researchers.

25 Sep 2013

Disturbances in body insulin levels linked with increased risk of obesity-related cancers

It is estimated that over a third of the new cancer cases expected to occur in the U.S. in 2013 will be related to overweight or obesity, physical inactivity, and poor nutrition. Thanks to the work of one NYU Steinhardt researcher, we may better understand why.

25 Sep 2013

Use of insulin pump with sensor reduces rate of severe hypoglycemia

Use of an insulin pump with a sensor that suspends insulin delivery when blood glucose falls below a set threshold reduced the rate of severe and moderate hypoglycemia among patients with type 1 diabetes and impaired awareness of hypoglycemia, according to a study in the September 25 issue of JAMA.

25 Sep 2013

Boehringer Ingelheim, Lilly present post-hoc analysis data from linagliptin clinical trials at EASD 2013

Boehringer Ingelheim and Eli Lilly and Company today announced results from two post-hoc, pooled analyses of data from placebo-controlled clinical trials, which examined the safety of the dipeptidyl peptidase-4 inhibitor linagliptin in adults with type 2 diabetes.

24 Sep 2013

Alefacept drug shows encouraging results in phase 2 trial for type 1 diabetes

A drug formerly used to treat the skin disorder psoriasis has shown encouraging results in a phase 2 trial to assess its effectiveness in treating type 1 diabetes, according to new research published in The Lancet Diabetes & Endocrinology.

24 Sep 2013

Understanding genetic, physiological basis for metabolic diseases related to circadian function

A new study by a team of University of Notre Dame researchers, which appears in the Sept. 2 edition of the journal PLoS ONE, is a significant step in understanding the molecular genetic and physiological basis for a spectrum of metabolic diseases related to circadian function.

24 Sep 2013

Rice University researchers come up with touch-to-access security for implanted devices

Pacemakers, insulin pumps, defibrillators and other implantable medical devices often have wireless capabilities that allow emergency workers to monitor patients. But these devices have a potential downside: They can be hacked.

24 Sep 2013

FDA's final guidance outlines tailored approach to mobile medical apps

Today, the U.S. Food and Drug Administration issued final guidance for developers of mobile medical applications, or apps, which are software programs that run on mobile communication devices and perform the same functions as traditional medical devices. The guidance outlines the FDA's tailored approach to mobile apps.

24 Sep 2013

Addition of walnuts to diet can protect against diabetes and heart disease in at-risk individuals

Medical researchers from the Yale-Griffin Prevention Research Center in Connecticut have found evidence suggestive that adding walnuts to one's diet can protect against diabetes and heart disease in at-risk individuals.

24 Sep 2013

Researchers report encouraging results from T1DAL study on type 1 diabetes

Encouraging results from the T1DAL study (Targeting effector memory T cells with alefacept in new onset type 1 diabetes), led by Mark R. Rigby MD, PhD from Indiana University and Riley Hospital for Children in Indianapolis and sponsored by the Immune Tolerance Network (ITN) with additional support from JDRF, are published today in The Lancet Diabetes & Endocrinology.

23 Sep 2013

CRF to present groundbreaking clinical trial findings at TCT 2013 scientific symposium

The Cardiovascular Research Foundation (CRF) has announced the late breaking trials and first report investigations that will be presented at next month's Transcatheter Cardiovascular Therapeutics (TCT) 2013 scientific symposium.

21 Sep 2013

DiaRem score predicts diabetes remission after gastric bypass

A new scoring system offers a “scientifically valid” way of predicting the 5-year likelihood for diabetes remission in patients undergoing gastric bypass surgery, say the researchers who developed the score.

20 Sep 2013

Insulin News and Research

Further Reading

New insights into how obesity, type 2 diabetes can create stress response in the brain

Insulin interaction map could lead to new therapeutic targets for type 2 diabetes

Study shows direct causative link between obesity and risk of pancreatic cancer in mice

Roadmap of protein interactions may lead to new therapeutic approaches for type 2 diabetes

Diabetes puts you at increased risk of flu-related complications

Diabetic patients at greater risk of breast, colon cancer

Study provides new insights into type 1 diabetes pathology

JDRF applauds FDA approval of Medtronic's MiniMed 530G with Enlite system for T1D

Study on tempol impacted gut bacteria may lead to new treatments for obesity

Disturbances in body insulin levels linked with increased risk of obesity-related cancers

Use of insulin pump with sensor reduces rate of severe hypoglycemia

Boehringer Ingelheim, Lilly present post-hoc analysis data from linagliptin clinical trials at EASD 2013

Alefacept drug shows encouraging results in phase 2 trial for type 1 diabetes

Understanding genetic, physiological basis for metabolic diseases related to circadian function

Rice University researchers come up with touch-to-access security for implanted devices

FDA's final guidance outlines tailored approach to mobile medical apps

Addition of walnuts to diet can protect against diabetes and heart disease in at-risk individuals

Researchers report encouraging results from T1DAL study on type 1 diabetes

CRF to present groundbreaking clinical trial findings at TCT 2013 scientific symposium

DiaRem score predicts diabetes remission after gastric bypass

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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