Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Nanomedicine can be improved with proper and more predictive in vitro assays

Messenger RNA (mRNA) vaccines are a prime example of the promising field of nanomedicine. But progress in the design and application of nanoparticles as efficient delivery vehicles for biopharmaceutics containing nucleic acid or protein drug substances is, unfortunately, remarkably slow.

1 Feb 2022

C-Path and EJP RD collaborate to expand global rare disease research and drug development

Critical Path Institute (C-Path), an independent global nonprofit organization, and the European Joint Programme on Rare Diseases (EJP RD), an initiative that has received funding from the European Union's Horizon 2020 research and innovation programme, have announced a collaboration to advance technologies and methodologies that are fit for regulatory purposes to further global rare disease research and drug development.

1 Feb 2022

Researchers identify genetic cause of rare interstitial lung disease in a young child

New research from Washington University School of Medicine in St. Louis has solved the medical mystery of why a 2-year-old child — seemingly healthy at birth — succumbed to an undiagnosed, rare illness.

31 Jan 2022

Study identifies drugs that could help combat mortality in patients with COVID-19

Inflammation is a defense mechanism of the body to fight pathogens. However, when it is widespread and excessive, it can aggravate the pathology and even cause death.

31 Jan 2022

Binding and conformational properties of the SARS-CoV spike protein and hACE2 complex

A new paper in the journal Molecules describes this in molecular terms, comparing SARS-CoV-2 with an earlier highly pathogenic coronavirus, SARS-CoV.

31 Jan 2022

Evidence on intra-host recombination of SARS-CoV-2 during superinfection by Alpha and Epsilon variants in USA

A new study captured an instance of SARS-CoV-2 superinfection in an individual, simultaneously infected by two SARS-CoV-2 variants, Alpha and Epsilon during the second COVID-19 wave in New York City in early 2021.

28 Jan 2022

New atlas characterizes immune cells that play a role in hemorrhagic stroke

In work that will enhance the study of such disparate diseases as stroke and dementia, researchers at UC San Francisco have catalogued all the cells that form the blood vessels of the human brain, along with their locations and the genes transcribed in each.

28 Jan 2022

Updated analysis helps clarify the relationship between alcohol consumption and epilepsy

Epilepsy, a common neurological disorder associated with stigma, psychiatric comorbidities, and rising healthcare costs, affects approximately 50 million people globally. A common risk factor associated with the development of epilepsy and seizures is alcohol consumption.

28 Jan 2022

ERGA aims to provide genomic data to inform research about Europe's biodiversity

To provide important genomic data to inform research about Europe's biodiversity, scientists from 48 different countries initiated the "European Reference Genome Atlas" (ERGA) in 2021.

28 Jan 2022

Cross-recognition of SARS-CoV-2 vaccine-elicited T cell responses among different variants

In a new study, researchers evaluated SARS-CoV-2 vaccination-induced T cell responses cross-recognition among the early and novel SARS-CoV-2 variants.

26 Jan 2022

New report investigates how genomics could play a part in our lives in the future

A new wide-ranging report Genomics Beyond Health published today by the Government Office for Science investigates how genomics could play a part in our lives in the future, from sport to education and tackling crime.

25 Jan 2022

The tetrapeptide tuftsin effectively impairs the binding of SARS-CoV-2 S1 to ACE2

In their recent study posted to the preprint server bioRxiv*, the researchers from China have shown that tuftsin, a natural phagocytosis-stimulating peptide, can effectively impair the binding of SARS-CoV-2 spike S1 subunit to ACE2 receptor in a dose-dependent manner and therefore can be considered a potential drug against SARS-CoV-2 infection.

20 Jan 2022

NIH-funded study will use machine learning to predict individual responses to diet

A new federally funded study will use machine learning to predict how an individual responds to a given diet, allowing physicians to offer patients personalized nutrition prescriptions to improve health and treat chronic diseases.

20 Jan 2022

NIH Common Fund supports Nutrition for Precision Health study

The National Institutes of Health is awarding $170 million over five years, pending the availability of funds, to clinics and centers across the country for a new study that will develop algorithms to predict individual responses to food and dietary routines.

20 Jan 2022

Exploring biological characteristics of SARS-CoV-2-induced myocardial damage

In a new study, researchers used bioinformatics tools to explore the biological characteristics of SARS-CoV-2-infected myocardium.

19 Jan 2022

Immune responses in Omicron breakthrough COVID-19

A recent study examined the question as to whether vaccination protects against Omicron infection by assessing breakthrough infection rates in participants at a superspreader event.

18 Jan 2022

AI-driven solution predicts RNA and DNA binding sites to accelerate rational drug discovery

The iMolecule group from Skoltech has developed an artificial intelligence-driven solution that uses data on the structure of RNA or DNA molecules to identify sites on them where interaction with potential drug candidates can occur.

11 Jan 2022

Optimal monoclonal antibodies against SARS-CoV-2 variants

Researchers screen different monoclonal antibodies to identify an optimal mAb with higher binding affinity to the receptor-binding domain of SARS-CoV-2.

10 Jan 2022

£10m Leverhulme Centre for the Holobiont aims to restore habitats and rescue endangered species

The £10m Leverhulme Centre for the Holobiont aims to create a green revolution in agriculture, rescue threatened species, and restore habitats.

10 Jan 2022

Researchers identify how a critical schistosomiasis drug works on the molecular level

Independent teams from Texas Biomedical Research Institute and the Medical College of Wisconsin have published two papers in Science Translational Medicine identifying how the only approved drug to treat schistosomiasis, a widespread parasitic worm infection, works on the molecular level.

6 Jan 2022

Bioinformatics News and Research

Further Reading

Nanomedicine can be improved with proper and more predictive in vitro assays

C-Path and EJP RD collaborate to expand global rare disease research and drug development

Researchers identify genetic cause of rare interstitial lung disease in a young child

Study identifies drugs that could help combat mortality in patients with COVID-19

Binding and conformational properties of the SARS-CoV spike protein and hACE2 complex

Evidence on intra-host recombination of SARS-CoV-2 during superinfection by Alpha and Epsilon variants in USA

New atlas characterizes immune cells that play a role in hemorrhagic stroke

Updated analysis helps clarify the relationship between alcohol consumption and epilepsy

ERGA aims to provide genomic data to inform research about Europe's biodiversity

Cross-recognition of SARS-CoV-2 vaccine-elicited T cell responses among different variants

New report investigates how genomics could play a part in our lives in the future

The tetrapeptide tuftsin effectively impairs the binding of SARS-CoV-2 S1 to ACE2

NIH-funded study will use machine learning to predict individual responses to diet

NIH Common Fund supports Nutrition for Precision Health study

Exploring biological characteristics of SARS-CoV-2-induced myocardial damage

Immune responses in Omicron breakthrough COVID-19

AI-driven solution predicts RNA and DNA binding sites to accelerate rational drug discovery

Optimal monoclonal antibodies against SARS-CoV-2 variants

£10m Leverhulme Centre for the Holobiont aims to restore habitats and rescue endangered species

Researchers identify how a critical schistosomiasis drug works on the molecular level

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