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Benefits of heterotypic vaccination against variants of SARS-CoV-2

A new study evaluated the antibody responses against the newly emerged SARS-CoV-2 Omicron variant upon heterotypic vaccination in animal models.

28 Mar 2022

Mathematical model of SARS-CoV-2 transmission tailored to the unique situation of China

Researchers designed a dynamic mathematical model to simulate the transmission of the SARS-CoV-2 Omicron variant in China and project its associated burden on healthcare facilities, should the zero-COVID-19 policy be lifted.

28 Mar 2022

Study evaluates receptor-binding domain antibodies for their ability to bind and neutralize Omicron

Researchers evaluated the ability of RBD antibodies to bind to and neutralize SARS-CoV-2 Omicron variant.

28 Mar 2022

Severe outcomes in hospitalized children during the Omicron BA.2-dominated fifth wave in Hong Kong

A recent study investigated the disease severity of SARS-CoV-2 Omicron BA.2 infection among Hong Kong children.

28 Mar 2022

Study finds fewer hospital visits for stroke in first year of COVID-19 pandemic

The first year of the COVID-19 pandemic saw fewer hospital visits for stroke, fewer stroke therapies, more treatment delays and a higher risk of in-hospital deaths in the subsequent COVID-19 waves, according to an Alberta study published in CMAJ.

28 Mar 2022

Which U.S. cities are most vulnerable to spread of COVID-19?

Now, researchers from New Jersey City University have been attempting to explore the same factors to identify vulnerability in U.S. cities. Their research, under consideration at the journal Scientific Reports, is currently available on the Research Square* preprint server.

28 Mar 2022

Frequent population screening can effectively reduce the transmission of SARS-CoV-2

In the face of the escalating fifth wave outbreak in Hong Kong, the government is planning a universal population screening that will combine antigen tests and PCR tests.

27 Mar 2022

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

A new research paper published as an early release manuscript in the Nature Medicine journal compares the sensitivity of this strain as well as the earlier Delta and the newer BA.2 to therapeutic mAbs.

27 Mar 2022

The effects of severe COVID-19 on the lungs after one year

While short-term lung damage has been reported in patients hospitalized with pneumonia caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), there is little data on the more chronic sequelae of this condition. A new research paper summarizes data from patients seen one year from discharge.

27 Mar 2022

Tuberculosis infection protects mice against COVID-19

To study if prior Mtb infection affects the response to CoV2 infection, K18-hACE2 (ACE2) and C57BL/6 (B6) mice were infected with Mtb, and post thirty days, were exposed to CoV2.

27 Mar 2022

SARS-CoV-2 antibodies in breast milk remain after Holder pasteurization

Researchers study the impact of pasteurization on specific Ig concentration against SARS-CoV-2 in milk from mRNA vaccinated lactating women.

27 Mar 2022

CDK6: a potential drug target for severe COVID-19

Researchers identify a methodology and workflow to repurpose drugs against the cyclin-dependent kinase 6 target gene of SARS-CoV-2.

27 Mar 2022

Clinical determinants of post-COVID-19 thromboembolism

Researchers quantify the risk of acute VTE due to SARS-CoV-2 infection in ambulatory settings.

27 Mar 2022

U.S. traveler-based genomic surveillance provided early SARS-CoV-2 variant detection

Researchers discuss their efforts to detect SARS-CoV-2 and its variants in travelers entering the United States.

27 Mar 2022

Researchers quantify salivary inflammatory mediators in COVID-19

Frank A. Boksa, University of Iowa College of Dentistry, Iowa City, IA, presented "Salivary Immune Signature of SARS-nCoV2 Infection" at the hybrid 51st Annual Meeting & Exhibition of the AADOCR, held in conjunction with the 46th Annual Meeting of the Canadian Association for Dental Research, online and onsite in Atlanta, GA, on March 26, 2022.

27 Mar 2022

HIV patients on antiretroviral treatment with protease inhibitors may have lower COVID-19 risk

A preliminary study to be presented at this year's European Congress of Clinical Microbiology & Infectious Diseases in Lisbon, Portugal (23-26 April), suggests that people living with HIV who are on antiretroviral treatment (ART) with protease inhibitors (PI), may have a lower risk of COVID-19 infection.

27 Mar 2022

Combination of Covid-19 and flu linked to greater risk of severe disease, death

Adults in hospital who have Covid-19 and the flu at the same time are at much greater risk of severe disease and death compared with patients who have Covid-19 alone or with other viruses, research shows.

27 Mar 2022

New method for generating binding proteins solves a long-standing challenge in drug development

A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable proteins on the surface of viruses.

25 Mar 2022

Novel SARS-CoV-2 strains found to have low impact on CD8 T lymphocytes

Researchers investigated the impact of mutations in the SARS-CoV-2 variants of interest and variants of concern on the properties of the cluster of differentiation 8 T lymphocytes.

25 Mar 2022

New insights into SARS-CoV-2 immunity gained from natural infection

Antibody-secreting cells (ASCs) peaked at 3-4 weeks and were still being produced at 3-4 months in patients hospitalized with COVID-19, according to a study published in the peer-reviewed journal Viral Immunology.

25 Mar 2022