Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Stat5 protein is particularly plentiful in high histological grade human prostate cancer

Prostate cancer is much more likely to be aggressive if a key protein called Stat5 is found activated and in abundance in the cancer cells, report researchers from Georgetown University's Lombardi Comprehensive Cancer Center.

15 Jul 2004

Latest findings on HIV pathogenesis at AIDS Conference in Bangkok

At the XVth International AIDS Conference in Bangkok, Thailand, Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases and chief of the NIAID Laboratory of Immunoregulation (LIR), will present his laboratory’s latest findings on how aberrant immune activation underlies HIV pathogenesis.

15 Jul 2004

New hereditary spastic paraplegia research

In work reported this week, researchers have taken our understanding of HSP to a new level with the development of an animal model for the disease.

13 Jul 2004

Study shows that in older age, myelin insulation breaks down, resulting in a decline in the speed and efficiency of our brain

UCLA neuroscientists using a new MRI analysis technique to examine myelin sheaths that insulate the brain's wiring report that as people age, neural connections that develop last degenerate first.

12 Jul 2004

Human antibodies that thwart the SARS virus in mice can be mass-produced quickly

Human antibodies that thwart the SARS virus in mice can be mass-produced quickly using a new laboratory technique developed by an international research team collaborating with the National Institute of Allergy and Infectious Diseases (NIAID).

12 Jul 2004

Genetic mutation is a major contributor to type 1 diabetes

A natural mutation of a gene that helps regulate the reactivity of the immune system is a major contributor to type 1 diabetes, Medical College of Georgia researchers have found.

12 Jul 2004

Myriad Genetics awarded a $14.2 million contract for AIDS and hepatitis research

Myriad Genetics has announced that it has been awarded a five-year, $14.2 million contract by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

10 Jul 2004

HHS strengthen safeguards against mad cow disease

HHS Secretary Tommy G. Thompson and Agriculture Secretary Ann M. Veneman has announced three actions being taken to further strengthen existing safeguards that protect consumers against the agent that causes bovine spongiform encephalopathy (BSE, also known as “mad cow disease”).

10 Jul 2004

First successful gene therapy that mimics the action of calcium channel blockers

Their findings - published in the latest edition of Circulation Research, online July 8 - may lead to a gene therapy alternative to calcium channel blockers and their sometimes severe side effects, but also further interest in the development of gene therapies unique - as in this case - to one particular organ.

10 Jul 2004

The structure of AGT shows how one human protein reduces the potency of chemotherapy

The fine details of this x-ray structure may help scientists find ways to fight certain cancers, such as brain tumors, which express high levels of AGT making them resistant to chemotherapy.

9 Jul 2004

Dexrazoxane reduces heart damage caused by childhood leukemia treatment with doxorubicin (Adriamycin)

A potent chemotherapy that is highly effective in treating the most common form of childhood leukemia can significantly harm the heart, but findings from a multi-center study

9 Jul 2004

Geographic variations in colour perception

It's long been known that color blindness is caused, usually in men, by changes in the red and green opsin genes, the genes that enable humans to perceive color.

9 Jul 2004

Mitochondria in spinal cords is Lou Gehrig’s disease target according researchers

The selective killing of spinal cord neurons in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, occurs when tiny cellular components called mitochondria actively recruit a mutant disease-causing protein into specific neuron cells, according to new research by University of California, San Diego (UCSD) School of Medicine investigators.

9 Jul 2004

Avian influenza virus in East Asia arose through a series of genetic reassortment events with other viruses

An avian influenza virus that has caused three major outbreaks among poultry and killed several people in East Asia over the past seven years arose through a series of genetic reassortment events with other viruses.

9 Jul 2004

Scientists have isolated human postnatal stem cells for the first time from the fibrous tendon that holds our teeth in their sockets

Scientists at the National Institute of Dental and Craniofacial Research (NIDCR), one of the National Institutes of Health, and their colleagues have isolated human postnatal stem cells for the first time directly from the periodontal ligament, the fibrous, net-like tendon that holds our teeth in their sockets.

8 Jul 2004

Identification of a naturally occurring genetic difference that controls the production of serotonin in the brain

Researchers at Duke University Medical Center have provided the first direct evidence in mice for the role of an enzyme that specifically controls the production of serotonin in the brain.

8 Jul 2004

Brazilian Government approves DuPont system that detects salmonella

The BAX® system, a genetics-based diagnostic tool developed by DuPont Qualicon, has been approved by the Ministry of Agriculture in Brazil as an Official Reference Method to detect Salmonella in food, water and environmental samples.

8 Jul 2004

Understanding the role of c-Jun in repairing damaged nerve cells could help treat spinal injuries and increase our understanding of cancer

Research into the action of a key cancer gene has serendipitously uncovered its vital role in nerve growth, Cancer Research UK scientists reveal in a paper published on Wednesday.

8 Jul 2004

Researchers shed new light on the function of huntingtin, the protein whose mutation underlies Huntington’s disease

CNRS and Inserm research scientists at the Institut Curie have shed new light on the function of huntingtin, the protein whose mutation underlies Huntington’s disease.

8 Jul 2004

Mediterranean diet lowers levels of markers for inflammation and coagulation which have been linked to heart disease

“The benefits of this diet are very well known, but the mechanism is not well understood. We believe this is the first time it has been reported that the potential mechanism goes through the inflammation process,” said Demosthenes B. Panagiotakos, MSc, PhD with Harokopio University in Athens, Greece.

7 Jul 2004

Protein News and Research

Further Reading

Stat5 protein is particularly plentiful in high histological grade human prostate cancer

Latest findings on HIV pathogenesis at AIDS Conference in Bangkok

New hereditary spastic paraplegia research

Study shows that in older age, myelin insulation breaks down, resulting in a decline in the speed and efficiency of our brain

Human antibodies that thwart the SARS virus in mice can be mass-produced quickly

Genetic mutation is a major contributor to type 1 diabetes

Myriad Genetics awarded a $14.2 million contract for AIDS and hepatitis research

HHS strengthen safeguards against mad cow disease

First successful gene therapy that mimics the action of calcium channel blockers

The structure of AGT shows how one human protein reduces the potency of chemotherapy

Dexrazoxane reduces heart damage caused by childhood leukemia treatment with doxorubicin (Adriamycin)

Geographic variations in colour perception

Mitochondria in spinal cords is Lou Gehrig’s disease target according researchers

Avian influenza virus in East Asia arose through a series of genetic reassortment events with other viruses

Scientists have isolated human postnatal stem cells for the first time from the fibrous tendon that holds our teeth in their sockets

Identification of a naturally occurring genetic difference that controls the production of serotonin in the brain

Brazilian Government approves DuPont system that detects salmonella

Understanding the role of c-Jun in repairing damaged nerve cells could help treat spinal injuries and increase our understanding of cancer

Researchers shed new light on the function of huntingtin, the protein whose mutation underlies Huntington’s disease

Mediterranean diet lowers levels of markers for inflammation and coagulation which have been linked to heart disease

A new way of characterising biomolecules eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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