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Study shows 90.7% efficacy for the BNT162b2 COVID vaccine in 5-11 year-olds

A new study evaluates the safety, immunogenicity, and efficacy of the BNT162b2 in children who were 5 to 11 years of age.

11 Nov 2021

Association between SARS-CoV-2 infections and areal level deprivation and ethnicity in England

A new study from the UK shows that the presence of inequality favors a heavier impact and that this showed dynamic changes as policies changed and newer virus variants emerged.

11 Nov 2021

COVID-19 trends identified from multiple linked EHR

In this study, the sociodemographic factors, occurrence of health conditions, the effect of the first and second waves in England, and vaccination effects, were considered separately.

11 Nov 2021

Corrected method for more accurate estimation of SARS-CoV-2 reproduction number

Scientists have recently proposed and applied a correction to EpiEstim, a statistical method to estimate the time-dependent transmission of infectious disease during an epidemic.

11 Nov 2021

REGEN-COV shown to rapidly reduce SARS-CoV-2 viral load in hospitalized COVID-19 patients

Studies have shown that mortality rates in hospitalized patients with COVID-19 are high, ranging between 10% and 30%. REGEN-COV®, a combination of monoclonal antibodies casirivimab and imdevimab, is approved in the United States and other regions for emergency treatment of COVID-19 outpatients with mild to moderate SARS-CoV-2 infection and post-exposure prophylaxis.

10 Nov 2021

Study finds high rates of asphyxia-associated neonatal mortality in poorer parts of São Paulo state

Researchers who analyzed data for São Paulo state, Brazil, found the highest rates of newborn mortality from asphyxia in cities in the south, southeast and north of the state between 2004 and 2013.

10 Nov 2021

ACTG announces launch of clinical trial evaluating a three-month TB treatment

The AIDS Clinical Trials Group (ACTG), the largest global HIV research network, today announced the launch of A5362 (CLO-FAST), a clinical trial studying a three-month clofazimine- and high-dose rifapentine-containing treatment regimen for people with drug-susceptible tuberculosis (TB).

10 Nov 2021

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

Researchers at Yale School of Medicine have discovered that an RNA molecule that stimulates the body's early antiviral defense system can protect mice from a range of emerging SARS-CoV-2 variants.

10 Nov 2021

Risk of severe COVID-19 is rare among fully vaccinated individuals in England

A team of UK-based scientists has recently estimated the prevalence of vaccine breakthrough infections and severe disease in a large number of individuals fully vaccinated against coronavirus disease 2019 (COVID-19) in England.

10 Nov 2021

Coronaviruses synthesize RNA in membrane-bound compartments

A team of researchers show that IBV viral RNA synthesis occurs within the membrane-bound compartment

10 Nov 2021

The SARS-CoV-2 Beta variant evades Fc effector function by ancestral strain, study says

A new study finds improved Fc cross-reactivity against certain SARS-CoV-2 variant of concern.

10 Nov 2021

The autoantibody profile in COVID-19 patients with MIS-C

A new study assessed the presence of autoantibodies against autoantigens associated with known autoimmune diseases in patients with COVID-19.

10 Nov 2021

Current understanding of the link between COVID-19 and cardiovascular disease

A review published in Chemo-Biological Interactions has focused on the prevalence of COVID-19 in CVD patients associated with ACE2 mechanisms.

10 Nov 2021

Western boom cities see spike in harmful ozone

The reduction of harmful ground-level ozone across most of the U.S. over the past several decades has been an air pollution success story.

10 Nov 2021

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

Despite clear directives outlined in the updated guidelines published by the American College of Rheumatology/National Psoriasis Foundation (ACR/NPF) in 2018, there is limited data regarding medication use in real-world clinical practice and patient medication preferences for the treatment of psoriatic arthritis (PsA).

9 Nov 2021

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

Leonard Imbula of the Healthy Mind Lab at Washington University School of Medicine in St. Louis holds a bottle of fluvoxamine, a psychiatric drug that has been shown, in a pair of studies conducted on two continents, to be an effective treatment for people sick with COVID-19.

9 Nov 2021

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine and MitoPower LLC were awarded an SBIR (Small Business Innovation Research) grant of up to $6.5 million over five years from the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism.

9 Nov 2021

COVID-19 drug candidate with wide-ranging antiviral activity

A new study investigated the antiviral activity and mechanism of action of Brilacidin against multiple human coronaviruses.

9 Nov 2021

Invalidation of potential SARS-CoV-2 protease inhibitors

Researchers identified several structurally disparate compounds that can inhibit the viral protease PLpro and determined whether the identified PLpro inhibitors are truly effective and should be further investigated.

9 Nov 2021

Study reveals cellular mechanism behind older adults' susceptibility to COVID-19

Among the populations most significantly affected by COVID-19 are the elderly and patients with preexisting medical conditions including diabetes, hypertension, obesity, metabolic syndrome, cardiovascular disease and chronic lung diseases like COPD and asthma.

8 Nov 2021

Mortality News and Research

Study shows 90.7% efficacy for the BNT162b2 COVID vaccine in 5-11 year-olds

Association between SARS-CoV-2 infections and areal level deprivation and ethnicity in England

COVID-19 trends identified from multiple linked EHR

Corrected method for more accurate estimation of SARS-CoV-2 reproduction number

REGEN-COV shown to rapidly reduce SARS-CoV-2 viral load in hospitalized COVID-19 patients

Study finds high rates of asphyxia-associated neonatal mortality in poorer parts of São Paulo state

ACTG announces launch of clinical trial evaluating a three-month TB treatment

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

Risk of severe COVID-19 is rare among fully vaccinated individuals in England

Coronaviruses synthesize RNA in membrane-bound compartments

The SARS-CoV-2 Beta variant evades Fc effector function by ancestral strain, study says

The autoantibody profile in COVID-19 patients with MIS-C

Current understanding of the link between COVID-19 and cardiovascular disease

Western boom cities see spike in harmful ozone

HSS study provides insight into real-world medication use for treatment of psoriatic arthritis

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

COVID-19 drug candidate with wide-ranging antiviral activity

Invalidation of potential SARS-CoV-2 protease inhibitors

Study reveals cellular mechanism behind older adults' susceptibility to COVID-19

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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