Cancer Immunotherapy News and Research

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Researchers identify new mechanism to resist fungal infection in cells

Indiana University researchers have identified a mechanism involving the body's ability to resist fungal infection. The work could help advance research on cancer therapies that use the body's own immune system to fight disease.

18 Nov 2019

Glutamine-blocking compound slows cancer growth, unleashes anti-tumor immune response

A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells.

10 Nov 2019

Genetic diversity impacts efficacy of cancer immunotherapy

The constant battle against infectious pathogens has had a decisive influence on the human immune system over the course of our evolution.

8 Nov 2019

New model could predict response of HIV-infected individuals to cancer immunotherapy

A group of researchers at UPF and the Marchuk Institute of Numerical Mathematics in Moscow, Russia, have designed a mathematical model to predict the response of HIV-infected individuals to a type of cancer immunotherapy.

7 Nov 2019

HIMC at Mount Sinai to evaluate therapeutic effects of novel cancer immunotherapy

The Human Immune Monitoring Center at the Icahn School of Medicine at Mount Sinai will apply cutting-edge high-throughput technologies to evaluate the therapeutic effects of Libtayo (cemiplimab-rwlc), a PD-1 antibody blockade developed by biotechnology company Regeneron Pharmaceuticals, Inc and Sanofi.

5 Nov 2019

Researchers develop new type of transposase protein with improved biochemical properties

The team, comprising researchers from the European Molecular Biology Laboratory, the Universitätsklinikum Würzburg and the Paul-Ehrlich-Institut, managed to design a new variant of the Sleeping Beauty transposase with dramatically improved biochemical properties.

4 Nov 2019

New cellular immunotherapy for cancers

A new study published in the journal Nature Communications on 22 October 2019 reports a new approach to cancer treatment that increases the immune capability of T lymphocytes against malignant cancers. This allows the T cells to successfully infiltrate and destroy these tumors. Animal trials have been completed and the researchers are planning clinical trials in human beings next.

26 Oct 2019

Disrupting key immune regulator boosts anti-tumor immunity, enables cancer clearance

The immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time restraining its activity to avoid inadvertently attacking the body's healthy tissues and organs.

23 Oct 2019

New study indicates a way to improve cancer immunotherapy

Cancer immunotherapy drugs trigger the body's immune system to attack tumors and have revolutionized the treatment of certain cancers, such as lymphoma, lung cancer and melanoma. Yet, while some patients respond well to the drugs, others don't respond at all. Cancer immunologists want to change that.

23 Oct 2019

University Of Minnesota opens clinical trial of first-of-its-kind NK cell cancer immunotherapy

A new cancer clinical trial has opened at the M Health Fairview University of Minnesota Medical Center that leverages the groundbreaking research on stem cells and natural killer cells done at the Masonic Cancer Center and applies it to attack acute myeloid leukemia and B-cell lymphoma.

21 Oct 2019

Creatine serves as a molecular battery to power killer T cells' fight against cancer

Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, serves as a molecular battery for immune cells by storing and distributing energy to power their fight against cancer, according to new UCLA research.

18 Oct 2019

Study represents a major step in seeking alternative cancer treatments for non-responders

Research led by VHIO's Alena Gros signposts a new, less invasive approach to identify killer T lymphocytes in patients with gastrointestinal tumors with low mutational burden who are refractory to approved immune-based treatments.

16 Oct 2019

Scientists develop more accurate method to find good targets for cancer immunotherapy

Ludwig Cancer Research scientists have developed a new and more accurate method to identify the molecular signs of cancer likely to be presented to helper T cells, which stimulate and orchestrate the immune response to tumors and infectious agents.

15 Oct 2019

Researchers reveal mechanism involved in altering DNA methylation in cancer

Understanding the mechanisms that mediate widespread DNA damage in the cancer genome is of great interest to cancer physicians and scientists because it may lead to improved treatments and diagnosis. In this study, a multi-institutional team led by researchers at Baylor College of Medicine has brought attention to genomic structural variation as a previously unappreciated mechanism involved in altering DNA methylation, a form of gene control, in human cancers.

15 Oct 2019

Ludwig scientists develop robust method to refine personalized cancer immunotherapy

14 Oct 2019

Mogrify raises additional $16 million to accelerate the development of life-saving cell therapies

Mogrify Ltd (Mogrify), a UK company aiming to transform the development of life-saving cell therapies, today announced the initial close of its Series A funding. The Company raised $16 million USD in this round, bringing the total investment to over $20 million USD to date.

14 Oct 2019

More sensitive electrophysiology tools needed to study cancer cell populations

Bioelectricity of Cancer, a special issue of the peer-reviewed journal Bioelectricity, has just been published. Two promising discoveries are well delineated: an ultra-sensitive tool to detect cancer and a new therapeutic target for cancer immunotherapy.

9 Oct 2019

New protein painting technology could transform drug discovery process

George Mason University researchers have discovered the exact location where two proteins responsible for hiding cancer cells from the immune system bind.

8 Oct 2019

NUS researcher invents novel transfection technique to deliver DNA into immune cells

Immunotherapy is a promising cancer treatment that uses genetically modified immune cells to fight cancer. It can be used as a primary treatment or in combination with other treatments such as radiation and chemotherapy to slow down or stop the growth of cancer cells and prevent them from spreading to other parts of the body.

4 Oct 2019

Texas Biomed researchers zeroing in on new way to target TB with $2.8 million NIH grant

Researchers at Texas Biomedical Research Institute are zeroing in on a new way to target tuberculosis infection. The National Institutes of Health has awarded a four-year, $2.8 million grant for scientists to study the role of lung macrophages (immune cells) in metabolic and inflammation responses to TB.

1 Oct 2019