Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Inhibition of protein glycosylation successfully prevents SARS-CoV-2 infection in vitro

A new study provides direct evidence that the oligosaccharides attached to the viral surface spike protein are essential for viral infection, offering new approaches to preventive and therapeutic drugs.

9 Feb 2021

Study provides insight into the genetic landscape of polycystic kidney disease in Ireland

A study has described genetic changes in patients with the most common form of hereditary kidney disease that affects an estimated 12.5 million people worldwide.

8 Feb 2021

Medical cannabis may reduce blood pressure in older adults, study shows

A new discovery by researchers from Ben-Gurion University of the Negev (BGU) and its affiliated Soroka University Medical Center shows that medical cannabis may reduce blood pressure in older adults.

8 Feb 2021

Researchers elucidate mechanism by which blood and lymph vessels remain separated

Researchers from Kumamoto University (Japan) have clarified the mechanism by which blood and lymph vessels remain segregated from one another after development.

6 Feb 2021

How does SARS-CoV-2 infect the pancreas?

To understand how SARS-CoV-2 infects the pancreas and investigate its effects, a team of researchers used the human iPSC (induced pluripotent stem cells)-derived pancreatic cultures and analyzed the post-infection cellular and molecular changes.

5 Feb 2021

Study shows how genetic mutations lead to kidney cysts in tuberous sclerosis complex

Tuberous sclerosis complex (TSC) afflicts as many as two million people around the world, affecting multiple organs, including lungs, brain, skin and kidneys. In about 80 percent of cases, it causes cysts and benign tumors to form in the kidney, eventually resulting in kidney failure.

5 Feb 2021

Greater muscle strength associated with lower risk of COVID-19 hospitalization

A new preprint research paper posted to the medRxiv* server discusses the results of a study exploring the relationship between increased muscle strength and hospitalization for severe COVID-19.

4 Feb 2021

Imaging SARS-CoV-2 with a helium ion microscope for the first time

Scientists at Bielefeld University's Faculty of Physics have succeeded for the first time in imaging the SARS-CoV-2 coronavirus with a helium ion microscope.

4 Feb 2021

Novel quantum sensor offers a new route to early diagnosis, preventive treatment

Oxygen is essential for human life, but within the body, certain biological environmental conditions can transform oxygen into aggressively reactive molecules called reactive oxygen species (ROS), which can damage DNA, RNA, and proteins.

4 Feb 2021

Hematological findings in Amazonian patients with COVID-19

To discriminate between patients with severe and non-severe COVID-19 quickly, researchers from Peru looked for prognostic signatures in the blood samples of COVID-19 patients. Virgilio E. Failoc-Rojas et al. examined laboratory results and clinical prognosis of COVID-19 patients from a hospital in the Peruvian Amazon.

3 Feb 2021

Prevalence of underlying medical conditions related to severe COVID-19 is higher among cancer survivors

New study finds more than half (56.4%) of cancer survivors in the United States reported having additional underlying medical conditions associated with severe COVID-19 illness.

3 Feb 2021

Early use of therapeutic anticoagulation does not improve survival of critically ill COVID-19 patients

Although abnormal blood clotting has been identified as one of the primary causes of death from COVID-19, early treatment in an intensive care unit (ICU) with therapeutic anticoagulation (anti-clotting) for adults who are critically ill with COVID-19 does not appear to improve chances of survival, and could do more harm than good by increasing the risk for major bleeding, a multicenter research group cautions.

3 Feb 2021

Biomarkers could help discriminate cancer therapy-associated kidney injury from other causes

A study by Mayo Clinic researchers published in Kidney International Reports finds that immune checkpoint inhibitors, may have negative consequences in some patients, including acute kidney inflammation, known as interstitial nephritis. Immune checkpoint inhibitors are used to treat cancer by stimulating the immune system to attack cancerous cells.

3 Feb 2021

In Austin, some try to address vaccine inequity, but a broad plan is elusive

Communities of color have been among the hardest hit during the pandemic. But advocates in Texas say those communities are likely to have a harder time getting the vaccine in the coming months, so they are urging local leaders to step in.

3 Feb 2021

Comprehensive study on prenatal causes of kidney disease in adults

A research group from Inselspital, Universitätsspital Bern and the University of Bern has published a comprehensive study on prenatal causes of kidney disease in adults in "Nature Communications".

3 Feb 2021

ECMO life-support therapy can increase odds of survival for critically-ill COVID-19 patients

COVID-19 has caused more than 2 million deaths worldwide since the World Health Organization declared it a pandemic in March 2020.

2 Feb 2021

Differences in immune response to SARS-CoV-2 determine disease severity, study finds

Researchers investigate host responses to SARS-CoV-2, respiratory syncytial virus (RSV), and influenza virus (IV) in the nasal mucosa in children and adults.

2 Feb 2021

New protein acts as trickster to neutralize COVID-19 infection in human kidney organoid

Decoy protein intercepts spike of coronavirus. Virus prevented from infecting human cells. Protein may be a new way to treat and prevent COVID-19.

1 Feb 2021

Urinary shedding of spike protein in COVID-19 patients

A team of scientists from the United States has recently revealed that about 25% of people with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop renal complications and that the viral spike protein can be detected in the urine samples of these patients. The study is currently available on the medRxiv* preprint server.

1 Feb 2021

Study uncovers new anti-inflammatory role for blood clot protein fibrinogen

Flinders University researchers have discovered a new anti-inflammatory role for well-known blood clot protein fibrinogen, which could support targeted new treatments for kidney, heart and other common diseases.

1 Feb 2021

Nephrology News and Research

Further Reading

Inhibition of protein glycosylation successfully prevents SARS-CoV-2 infection in vitro

Study provides insight into the genetic landscape of polycystic kidney disease in Ireland

Medical cannabis may reduce blood pressure in older adults, study shows

Researchers elucidate mechanism by which blood and lymph vessels remain separated

How does SARS-CoV-2 infect the pancreas?

Study shows how genetic mutations lead to kidney cysts in tuberous sclerosis complex

Greater muscle strength associated with lower risk of COVID-19 hospitalization

Imaging SARS-CoV-2 with a helium ion microscope for the first time

Novel quantum sensor offers a new route to early diagnosis, preventive treatment

Hematological findings in Amazonian patients with COVID-19

Prevalence of underlying medical conditions related to severe COVID-19 is higher among cancer survivors

Early use of therapeutic anticoagulation does not improve survival of critically ill COVID-19 patients

Biomarkers could help discriminate cancer therapy-associated kidney injury from other causes

In Austin, some try to address vaccine inequity, but a broad plan is elusive

Comprehensive study on prenatal causes of kidney disease in adults

ECMO life-support therapy can increase odds of survival for critically-ill COVID-19 patients

Differences in immune response to SARS-CoV-2 determine disease severity, study finds

New protein acts as trickster to neutralize COVID-19 infection in human kidney organoid

Urinary shedding of spike protein in COVID-19 patients

Study uncovers new anti-inflammatory role for blood clot protein fibrinogen

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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