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Study points to importance of MYC gene in cancer progression

The cancer gene MYC is among the most commonly overexpressed oncogenes in human cancers. Most human cancers demonstrate high levels of MYC or its biological partners, including those of the breast, ovaries, lung, prostate, and skin, as well as leukemias and lymphomas.

19 Sep 2005

Researchers detail molecular images of a piece of the spike-shaped protein that the SARS virus uses initiate the first stages of infection

Researchers have determined the first detailed molecular images of a piece of the spike-shaped protein that the SARS virus uses to grab host cells and initiate the first stages of infection.

19 Sep 2005

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Researchers at The University of Texas M. D. Anderson Cancer Center and The University of Texas Health Science Center at Houston have found that human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke.

19 Sep 2005

Scientists have discovered a new and potent anti-cancer compound in beans

Scientists have discovered a new and potent anti-cancer compound in everyday food. The collaborative study led by UCL (University College London) shows that the compound - inositol pentakisphosphate - found in beans, nuts and cereals inhibits a key enzyme (phosphoinositide 3-kinase) involved in tumour growth.

19 Sep 2005

New research will play a major role in improving the future of breast cancer treatment

Cancer specialists at University of East Anglia have discovered that several 'ADAMTS' genes are turned off in breast cancer compared to normal breast tissue, while others are switched on. These genes could be targets for the development of 'smart' drugs tailored to treat individual patients' tumours.

19 Sep 2005

Natural daily body rhythms may influence the effectiveness of spinal-epidural pain medication

The study found that women who had day labor got longer pain relief than women with night labor with the same amount of labor pain medicine.

19 Sep 2005

46,000 crack cocaine users aged 15-44 in London

Researchers believe there could be 46,000 crack cocaine users aged 15-44 in London, suggesting one in every hundred young adult Londoners could be a user.

19 Sep 2005

Researchers selectively knock out memory associations connected with receiving cocaine

Addicts crave drugs and suffer relapse not just because of the alluring high of drugs, but also because they are compelled by the powerful, haunting memory associations with the environment surrounding their drug taking. Thus, treatments that could eliminate those memory associations could prove effective in treating addiction, researchers believe.

19 Sep 2005

In some poor countries, free life-saving HIV medicines are being given preferentially to patients

...who have never taken them before (so-called 'treatment-naive patients'), which could have disastrous consequences, says a team of researchers in Uganda.

19 Sep 2005

Cost-cutting strategy employed by HMOs for 15 years is simply not working

With rising concern over the cost of the new Medicare prescription drug benefit program – going into effect January, 2006 and estimated to cost $593 billion over the next decade – a new UCSF study reveals that a key cost-cutting strategy employed by HMOs for 15 years is simply not working.

19 Sep 2005

Cellular mechanism discovery could lead to new treatments for rheumatoid arthritis, multiple sclerosis and Crohn's disease

A major finding by researchers at the La Jolla Institute for Allergy & Immunology (LIAI) has identified a previously unknown cellular mechanism that acts as an off switch for immune system function.

12 Sep 2005

Screening test for cells that activate immune system

UT Southwestern Medical Center researchers are the first to create a large-scale, cell-based screening method that identifies which compounds activate immune-response cells that hold promise for future cancer-fighting vaccines.

12 Sep 2005

Generex Biotechnology granted Canadian patent

Generex Biotechnology Corporation has announced that it has been granted a patent by the Canadian Intellectual Property Office titled "Mixed Micellar Delivery System and Method of Preparation."

12 Sep 2005

Nuclear receptor proteins could change anti-inflammatory treatments

Several nuclear receptor proteins appear to overlap in their ability to exert anti-inflammatory effects, according to new research by scientists at the University of California, San Diego (UCSD).

12 Sep 2005

Amantadine resistant avian influenza viruses more common in Southeast Asia than North America

Resistance to the antiviral drug amantadine is spreading more rapidly among avian influenza viruses of H5N1 subtype in Southeast Asia than in North America, according to the study done by investigators at St. Jude Children's Research Hospital.

12 Sep 2005

Clioquinol appears to block the genetic action of Huntington's disease

Clioquinol, an antibiotic that was banned for internal use in the United States in 1971 but is still used in topical applications, appears to block the genetic action of Huntington's disease in mice and in cell culture, according to a study reported by San Francisco VA Medical Center (SFVAMC) researchers.

12 Sep 2005

Key cellular switch that controls glucose production in liver cells

In many patients with type 2 diabetes, the liver acts like a sugar factory on overtime, churning out glucose throughout the day, even when blood sugar levels are high. Scientists at the Salk Institute for Biological Studies discovered a key cellular switch that controls glucose production in liver cells.

12 Sep 2005

Drugs News and Research

Study points to importance of MYC gene in cancer progression

Researchers detail molecular images of a piece of the spike-shaped protein that the SARS virus uses initiate the first stages of infection

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Scientists have discovered a new and potent anti-cancer compound in beans

New research will play a major role in improving the future of breast cancer treatment

Natural daily body rhythms may influence the effectiveness of spinal-epidural pain medication

46,000 crack cocaine users aged 15-44 in London

Researchers selectively knock out memory associations connected with receiving cocaine

In some poor countries, free life-saving HIV medicines are being given preferentially to patients

Cost-cutting strategy employed by HMOs for 15 years is simply not working

Cellular mechanism discovery could lead to new treatments for rheumatoid arthritis, multiple sclerosis and Crohn's disease

Screening test for cells that activate immune system

Generex Biotechnology granted Canadian patent

Nuclear receptor proteins could change anti-inflammatory treatments

Amantadine resistant avian influenza viruses more common in Southeast Asia than North America

Clioquinol appears to block the genetic action of Huntington's disease

Key cellular switch that controls glucose production in liver cells

Genetic basis for susceptibility to alcohol abuse confirmed

A breakthrough in R&D for neglected diseases

Cannabis drug could help fight obesity

Drug Discovery - Second Edition eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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