Immune System News and Research

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Cats’ immune system can deal with SARS-CoV-2, shows study

On 8 May 2020, the Institute of Agrifood Research and Technology (IRTA) reported the case of the first cat infected with SARS-CoV-2 in Spain. It was a 4-year-old cat called Negrito, who lived with a family affected by COVID-19, with one case of death.

22 Sep 2020

Nanoparticle SARS-CoV-2 model could potentially speed the search for drugs

A team of scientists from the National Center for Advancing Translational Sciences and Naval Research Laboratory in Washington, D.C., has developed a new tool that mimics how SARS-CoV-2 -- the virus that causes COVID-19 -- infects a cell, information that could potentially speed the search for treatments against the disease.

22 Sep 2020

Impaired cytotoxic T cell response found in in elderly COVID-19 patients

Although people of any age can become infected with SARS-CoV-2, the virus that causes COVID-19, elderly patients face a higher risk of severity and death than younger patients.

22 Sep 2020

Consumption of cooked carrots can also trigger allergic reactions, finds study

The consumption of raw carrots triggers allergic reactions in many people. Contrary to popular belief, cooked carrots can also have this effect.

21 Sep 2020

BU researchers find how SARS-CoV-2 infection may drive deadly lung inflammation

Responding to the COVID-19 pandemic caused by the novel coronavirus, SARS-CoV-2, requires models that can duplicate disease development in humans, identify potential targets and enable drug testing.

21 Sep 2020

Study: Greater exercise capacity is linked to decreased mortality risk in people with type 2 diabetes

New research presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD), held online this year, shows that having a greater exercise capacity is associated with a significantly decreased all-cause mortality risk of between 25-33% in people with type 2 diabetes (T2D).

21 Sep 2020

SARS-CoV-2 infects monocytes and macrophages, without cytopathic effect

A team of researchers from Aix-Marseille Univ, IHU-Méditerranée Infection, Institut Paoli Calmettes and Laboratoire d’Immunologie, Marseille, France, conducted experiments to determine if SARS-CoV-2 can affect the myeloid compartment or infect monocytes and macrophages.

20 Sep 2020

Study identifies new regions of positive selection in SARS-CoV-2

Based on structural modeling of ribonucleic acid (RNA) and proteins, the researchers from Duke University argue that newly identified regions of positive selection in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) likely affect species-specific RNA instead of protein function – improving our understanding of the molecular mechanisms responsible for highly unique biological properties of this virus.

20 Sep 2020

New insights into human genetics

Who are we? Where did we come from? How did we get here? Throughout the ages, humans have sought answers to these questions, pursuing wisdom through religion, philosophy, and eventually science.

19 Sep 2020

Discovery could help enhance the effectiveness of immunotherapy against melanoma

Researchers at the University of Bern have discovered a mechanism in the body’s own immune system which is responsible for the maturation and activation of immune cells.

19 Sep 2020

Enhancing the efficacy of anti-PD-L1 immunotherapy for cancer

For most people, there is no scarier diagnosis than that of cancer. While treatments including chemotherapy and radiotherapy have been used since the 1940s and late 1800s, respectively, immunotherapy has more recently emerged as a viable and successful approach to cancer treatment.

18 Sep 2020

Ineffective immune responses may be responsible for COVID-19 mortality rates in men and the elderly

News-Medical speaks to Dr. Nicole Lieberman about her latest research that discovered delayed immune responses may affect COVID-19 mortality rates.

18 Sep 2020

Cellular recyclers could be used to eliminate the driver of cancer's aggressiveness

"Do not erase." "Recycle me." "Free to a good home." Humans post these signs to indicate whether something has value or not, whether it should be disposed of or not.

18 Sep 2020

Animal data supports efficacy of baricitinib vs SARS-COV-2

The high burden of disease caused by the COVID-19 pandemic has led to much research on effective ways to mitigate the health, social, and economic impact of the spread of the infection. A recent study published on the preprint server bioRxiv* in September 2020 reports on the characteristics of the drug baricitinib when used as monotherapy to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Sep 2020

T cells on the front line of COVID-19 response

In the new study, published in the journal Cell, the team has found that the uncoordinated responses produced by the immune system, especially in people who are more than 65 years old, maybe the reason why older adults are more at risk.

17 Sep 2020

CNIC researchers uncover a mechanism explaining how macrophages regulate obesity

Macrophages are immune system cells. They are essential in the early response to infections, and they also have a key role in the proper functioning of our tissues and the regulation of obesity.

17 Sep 2020

Smart drug delivery system may help treat spinal cord injuries, neurological disorders

A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders.

17 Sep 2020

Study promises to improve the efficacy of cell therapies

Researchers have gained a better understanding of the complexity of the environment in which T cells thrive and, by extension, the tolerance mechanisms of these cells which are an obstacle to cellular immunity.

17 Sep 2020

Study: T cells play a vital role in controlling SARS-CoV-2 during acute phase of infection

Ever since SARS-CoV-2 first appeared, researchers have been trying to understand whether sometimes the immune system does more harm than good during the acute phase of COVID-19. The latest study by researchers at La Jolla Institute for Immunology clearly argues in favor of the immune system.

17 Sep 2020

Study shows why bacterial cells behave differently on different types of surfaces

These results from studies in both experimental and theoretical physics may help to improve antibacterial surfaces. The research work was recently published in the journal 'Nanoscale'.

17 Sep 2020

Immune System News and Research

Cats’ immune system can deal with SARS-CoV-2, shows study

Nanoparticle SARS-CoV-2 model could potentially speed the search for drugs

Impaired cytotoxic T cell response found in in elderly COVID-19 patients

Consumption of cooked carrots can also trigger allergic reactions, finds study

BU researchers find how SARS-CoV-2 infection may drive deadly lung inflammation

Study: Greater exercise capacity is linked to decreased mortality risk in people with type 2 diabetes

SARS-CoV-2 infects monocytes and macrophages, without cytopathic effect

Study identifies new regions of positive selection in SARS-CoV-2

New insights into human genetics

Discovery could help enhance the effectiveness of immunotherapy against melanoma

Enhancing the efficacy of anti-PD-L1 immunotherapy for cancer

Ineffective immune responses may be responsible for COVID-19 mortality rates in men and the elderly

Cellular recyclers could be used to eliminate the driver of cancer's aggressiveness

Animal data supports efficacy of baricitinib vs SARS-COV-2

T cells on the front line of COVID-19 response

CNIC researchers uncover a mechanism explaining how macrophages regulate obesity

Smart drug delivery system may help treat spinal cord injuries, neurological disorders

Study promises to improve the efficacy of cell therapies

Study: T cells play a vital role in controlling SARS-CoV-2 during acute phase of infection

Study shows why bacterial cells behave differently on different types of surfaces

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