Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Scientists develop predictive computer model to alert surges in COVID-19 infections and mortalities

A team of scientists from Nanyang Technological University, Singapore (NTU Singapore) has developed a predictive computer model that, when tested on real pandemic data, proposed strategies that would have reduced the rate of both COVID-19 infections and deaths by an average of 72 percent, based on a sample from four countries.

16 Sep 2021

Study pinpoints a potential pathway for treating epileptic seizures in patients with autism

Autism affects about 2% of children in the United States, and about 30% of these children have seizures. Recent large-scale genetic studies revealed that genetic variants in a sodium channel, called voltage-gated sodium channel Nav1.2, is a leading cause of autism.

15 Sep 2021

A protein found to be effective at reversing aging in skeletal muscle cells

A University at Buffalo-led research team has shown that a protein named for the mythical land of youth in Irish folklore is effective at reversing aging in skeletal muscle cells.

15 Sep 2021

RIT study uncovers new information about how coronavirus attaches itself to human cells

Rochester Institute of Technology scientists have uncovered new information about the way coronavirus and several of its variants attach to human cells.

13 Sep 2021

USC Stevens INI launches a $3 million study to solve some puzzles about Parkinson's disease

The USC Mark and Mary Stevens Neuroimaging and Informatics Institute (USC Stevens INI), part of the Keck School of Medicine of USC, has launched a $3 million study that will unite researchers and data from 20 countries to answer some of the most pressing questions about Parkinson's disease (PD).

11 Sep 2021

Duke/UNC awarded NIH funding to establish prestigious Alzheimer's Disease Research Center

Duke University and the University of North Carolina at Chapel Hill have been awarded funds from the National Institutes of Health to establish a prestigious Alzheimer's Disease Research Center (ADRC), part of a federally-funded national network of similar centers.

9 Sep 2021

Scientists model the process of capsid disassembly in hepatitis B virus at atomic level

With up to 2.4 million U.S. cases and over 250 million chronic cases globally, hepatitis B infection persists despite the availability of a vaccine.

8 Sep 2021

Research reveals a previously unknown role for a key transcription regulator linked to cancer

CTCF is a transcription factor that has been a research target due to its role in regulating a critical oncogene called MYC.

7 Sep 2021

Liquid biopsies could help identify, track bladder cancer and peripheral nerve tumors

Liquid biopsies detect tumor DNA in blood or urine samples. Two studies led by Washington University School of Medicine in St. Louis describe the potential of liquid biopsies to identify and track tumor growth in two very different cancers: bladder cancer and peripheral nerve tumors.

31 Aug 2021

Hormones play a vital role in the development of breast cancer

A study by RCSI University of Medicine and Health Sciences has provided greater insight into the role that hormones play in the development of breast cancer in patients. The novel findings could enhance the treatment for breast cancer, assisting clinicians in optimising individual patient care and improving overall survival rates for patients.

31 Aug 2021

AI approach helps identify heart failure patients who will benefit from beta-blocker therapy

Researchers at the University of Birmingham have developed a new way to identify patients with heart failure who will benefit from treatment with beta-blockers.

31 Aug 2021

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Genomics, proteomics, metabolomics, transcriptomics -- rapid advances in high-throughput biomedical technologies has enabled the collection of data with unprecedented detail from the growing number of omics.

27 Aug 2021

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School of Medicine reveal in a paper published today in Nature Medicine.

26 Aug 2021

Dotmatics Appoints Michael Swartz as Senior Vice President Enterprise Product to Support Continued Rapid Growth

Dotmatics Ltd today announced it has appointed Michael Swartz to lead its Enterprise Product Strategy and Management functions.

From Dotmatics 24 Aug 2021

Study investigates the effects of calycosin on breast cancer cell progression

Aging-US published "Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-β1" which reported that in this study, the authors investigated the effects of calycosin on breast cancer cell progression and their underlying mechanisms. Calycosin dose- and time-dependently inhibited proliferation, migration, and invasion by T47D and MCF-7 breast cancer cells by downregulating basic leucine zipper ATF-like transcription factor expression.

23 Aug 2021

New PULSAR radiation-therapy strategy achieves better tumor control

Artificial intelligence, along with a $71-million expansion of Radiation Oncology services, is allowing UT Southwestern Medical Center cancer physicians to pioneer a new PULSAR radiation-therapy strategy that improves tumor control compared with traditional daily therapy.

From Elekta 20 Aug 2021

SARS-CoV-2 lambda variant escapes immune response via spike mutations

A new study explores the mechanism by which the SARS-CoV-2 lambda variant has acquired immune evasion capabilities above that of the wildtype.

20 Aug 2021

HMGA1 plays role in gastric cancer cell proliferation and metastasis

Aging-US published "HMGA1 promotes gastric cancer growth and metastasis by transactivating SUZ12 and CCDC43 expression" which reported that HMGA1 is overexpressed in GC cells and the high expression of HMGA1 was correlated with worse survival in GC patients using a bioinformatics assay.

19 Aug 2021

MD Anderson receives nearly $13 million from CPRIT to support research efforts

The University of Texas MD Anderson Cancer Center has been awarded $12.75 million from the Cancer Prevention and Research Institute of Texas to support basic, clinical, translational and prevention research efforts, including $3 million for a new project to build clinical trial network infrastructure across Texas.

19 Aug 2021

SARS-CoV-2 ORF8 and the expression of cytokine in human macrophages

A new study has determined the production of the SARS-CoV-2 SP-dependent ORF8.

18 Aug 2021

Bioinformatics News and Research

Further Reading

Scientists develop predictive computer model to alert surges in COVID-19 infections and mortalities

Study pinpoints a potential pathway for treating epileptic seizures in patients with autism

A protein found to be effective at reversing aging in skeletal muscle cells

RIT study uncovers new information about how coronavirus attaches itself to human cells

USC Stevens INI launches a $3 million study to solve some puzzles about Parkinson's disease

Duke/UNC awarded NIH funding to establish prestigious Alzheimer's Disease Research Center

Scientists model the process of capsid disassembly in hepatitis B virus at atomic level

Research reveals a previously unknown role for a key transcription regulator linked to cancer

Liquid biopsies could help identify, track bladder cancer and peripheral nerve tumors

Hormones play a vital role in the development of breast cancer

AI approach helps identify heart failure patients who will benefit from beta-blocker therapy

New MOGONET outperforms existing supervised multi-omics integrative analysis approaches

Neuroinflammation is the key upstream mechanism in Alzheimer’s disease progression

Dotmatics Appoints Michael Swartz as Senior Vice President Enterprise Product to Support Continued Rapid Growth

Study investigates the effects of calycosin on breast cancer cell progression

New PULSAR radiation-therapy strategy achieves better tumor control

SARS-CoV-2 lambda variant escapes immune response via spike mutations

HMGA1 plays role in gastric cancer cell proliferation and metastasis

MD Anderson receives nearly $13 million from CPRIT to support research efforts

SARS-CoV-2 ORF8 and the expression of cytokine in human macrophages

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