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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Advancements in the Optimization of Medical Accelerators

Radiotherapy is a way of treating cancer by means of radiation. In principle, that can be all different types of radiation. The commonly known types are X-rays or electron beams, which find very widespread application.

11 Jun 2020

Using nanotheranostics approach to treat cancer

The concept of theranostics revolves around the stratification of patients into specific groups based on their response to different treatments and their disease risks.

10 Jun 2020

Researchers evaluate survivin expression in neuroendocrine tumors

Volume 11, Issue 23 of @Oncotarget reported that tissue microarrays of 132 patients were stained for survivin using immunohistochemistry and correlated with outcomes.

10 Jun 2020

Key recommendations on genetic testing of men for prostate cancer

Prostate cancer is a leading cause of death from cancer in the US and especially in the Philadelphia region. Consistently, Philadelphia has outpaced the state of PA and the nation in diagnoses and death from prostate cancer.

10 Jun 2020

Twist Bioscience and Serimmune collaborate to identify SARS-CoV-2 therapeutic antibody candidates

Twist Bioscience Corporation, a company enabling customers to succeed through its offering of high-quality synthetic DNA using its silicon platform, and Serimmune Inc., a leader in understanding the functional antibody repertoire’s role in human disease, today announced a collaboration to identify and evaluate SARS-CoV-2 therapeutic antibody candidates from Twist libraries.

From Twist Bioscience 10 Jun 2020

Studies show prognostic value for circulating tumor cells in advanced prostate and breast cancer

Menarini Silicon Biosystems, the pioneer of liquid biopsy and single cell technologies, announced today that results from a new study presented at the virtual 2020 meeting of the American Society of Clinical Oncology suggest that circulating tumor cell counts may be useful in determining long-term prognosis and guiding treatment selection in patients with metastatic castrate sensitive prostate cancer.

10 Jun 2020

Promega announces CE marking for OncoMate MSI Dx Analysis System in Europe

Promega Corporation today announced CE marking for the OncoMate MSI Dx Analysis System as a new in vitro diagnostic medical device in Europe.

From Promega Corporation 10 Jun 2020

Plasmodium parasites have timekeeping systems that maintain their cell cycle activities

The parasites responsible for malaria seem to march to their own beat.The mystery behind the molecular basis of how these parasites synch their rhythm in replication to the host's clock-driven rhythms has been solved.

10 Jun 2020

New insights on DNA replication can help develop novel cancer treatments

A study by the Centre for Chromosome Biology at NUI Galway, Ireland, in partnership with the University of Zurich, has uncovered new insights into how the replication of DNA occurs which can be applied to help develop novel cancer treatments.

10 Jun 2020

Study provides molecular explanation to a longstanding mystery in viral oncology

The oncogenic herpesvirus (HHV8 or KSHV) causes a cancer known as Kaposi's Sarcoma. An international team of scientists led by the University of Helsinki has discovered key factors that control the genome maintenance and replication of a virus responsible for lymphatic vascular cancer.

10 Jun 2020

Deep UV LED inactivation of SARS-CoV-2 - fast and effective

The ongoing pandemic has aroused considerable effort to find methods to prevent and control the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19 disease. Rapid inactivation devices would be of great help in this area, to prevent viral transmission through aerosols and contact with infected surfaces.

9 Jun 2020

Study unravels role of a protein in osteoclast generation

Bone-dissolving cells called osteoclasts are derived from a type of immune cells called macrophages. They are necessary for the maintenance and renewal of bones.

9 Jun 2020

Exposure to flame retardant impacts paternal reproduction

A new study from the University of Georgia has shown that exposure to a now-banned flame retardant can alter the genetic code in sperm, leading to major health defects in children of exposed parents.

9 Jun 2020

New technique to identify genes implicated in the development of malignant brain tumor

Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma - a malignant brain tumor with a very poor prognosis. The study is published in Genome Biology.

9 Jun 2020

Better testing could lead to improved treatments for a specific type of ovarian cancer

Scientists have found that a specific type of ovarian cancer could possibly benefit from existing platinum-based chemotherapy and new DNA repairing treatments, following better testing.

8 Jun 2020

Researchers confirm new therapeutic target for myelodysplastic syndrome

A research group from Kumamoto University, Japan analyzed the pathophysiology of myelodysplastic syndrome (MDS), a blood cancer that presents often in the elderly, and found the presence of the transcription factor RUNX3, thereby revealing a cancer growth function for what had been considered a tumor suppressor.

8 Jun 2020

Study links a specific procedure to pregnancy complications in assisted reproduction

An experimental study from researchers in the Perelman School of Medicine at the University of Pennsylvania links a specific procedure - embryo culture - that is part of the assisted reproduction process (ART) to placental abnormalities, risk for preeclampsia, and abnormal fetal growth.

8 Jun 2020