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Next-Generation Sequencing and the Diagnosis of Disease

In this interview, Professor John Rossen talks about next-generation sequencing and it's implications for the diagnosis of disease.

From Tecan 4 Aug 2021

Biolabs LA at The Lundquist Institute reaches highly significant capacity milestone

BioLabs LA at The Lundquist Institute, a co-working and incubator facility for high-potential bioscience start-ups, has reached 100% capacity ahead of schedule.

3 Aug 2021

Diagnosis of viral infections using micro and nanoscale technologies

In a recent study, the authors provide a review on both micro- and nanoscale technologies that advanced the diagnosis of viral diseases.

3 Aug 2021

Study shows COVID-19 organ-specific outcomes depend on anti-spike glycoprotein antibodies

A recent study from the University of Rochester reveals how the biodistribution kinetics and the affinity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for many different organs in the human body can be affected by antibodies targeting viral spike glycoprotein. The paper is currently available on the bioRxiv* preprint server while it undergoes peer review.

3 Aug 2021

Comprehensive review: Nanomaterial-based delivery vehicles for cancer vaccine development

Over the years, significant advancements in cancer research have led us to the next step in cancer therapy – vaccines for cancer! However, the direct use of these vaccines in the affected individuals have often failed to bring about desired anti-tumor effects.

3 Aug 2021

PROTEIN-ID project aims to develop a device able to generate identity card of proteins

A device able to generate proteins identity card: this is the ambitious goal of the "PROTEIN ID" project, funded by the European Union with about 3 million euro for the next 3 years and coordinated by the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology).

3 Aug 2021

Open-access database could speed up repurposing of old drugs as new treatments

Researchers have created a new open-access database of information on drug candidates and how they are metabolized by the body, which could help speed up the repurposing of old drugs as new treatments.

3 Aug 2021

NSF awards $441,028 to address the workforce needs of regenerative medicine

Regenerative medicine is a cross-disciplinary field that aims to repair or replace abnormal organs by growing tissues in the laboratory or cells for therapy.

3 Aug 2021

Study conducts systematic review of the pre- and asymptomatic SARS-CoV-2 transmission

Researchers at Oxford University, UK, have conducted a systematic review of the available studies to address the role of presymptomatic and asymptomatic transmission of SARS-CoV-2.

3 Aug 2021

New breath test to tailor the dosage of drugs administered to epileptic patients

Epilepsy affects some 50 million people worldwide and pharmaceutical treatment of the disease is a tightrope walk, as the dose must be tailored precisely to the individual patient: "Slightly too little and it isn't effective. Slightly too much and it becomes toxic," explains Professor Pablo Sinues.

3 Aug 2021

CDC scientists model the most efficient physical barrier against SARS-CoV-2 for worker protection

Size doesn’t matter — when it comes to physical barriers in the workplace. A new Centers for Disease Control and Prevention (CDC) study found larger barriers were not statistically better than smaller physical barriers in protecting against severe acute respiratory syndrome 2 (SARS-CoV-2).

2 Aug 2021

Antibiotic-resistant salmonella bacteria packs a punch for U.S. travelers

One type of the salmonella bacteria is much more likely to cause disease and fend off frontline antibiotics when acquired in Europe, Asia, and parts of Africa rather than domestically in the United States.

2 Aug 2021

Existing drug may be effective in treating SARS-CoV-2

Scientists from the University of Chicago have found that the drug masitinib may be effective in treating COVID-19.

2 Aug 2021

New discovery could pave the way towards therapeutic treatments for many cancers

Princess Margaret Cancer Centre researchers have made new findings which provide a broader understanding of how dormant hematopoietic stem cells are activated and could pave the way towards therapeutic treatments for a number of cancers.

2 Aug 2021

UT Southwestern discovers the Achilles’ heel in ovarian cancers and potential biomarkers

UT Southwestern faculty have discovered what appears to be an Achilles' heel in ovarian cancers, as well as new biomarkers that could point to which patients are the best candidates for possible new treatments.

30 Jul 2021

New collaboration aims to boost vaccines manufacturing capability in South Africa

The Medicines Patent Pool and the World Health Organization, Afrigen Biologics Limited, the Biologicals and Vaccines Institute of Southern Africa, the South African Medical Research Council and Africa Centres for Disease Control and Prevention have signed a letter of intent to address the global imbalance of manufacturing capacity for COVID-19 vaccines.

30 Jul 2021

New understanding of the brain’s relay station could change medical treatment for brain disorders

New research shows cells gather more data than once believed inside the thalamus, a relay station of sensory and motor abilities in the brain. That could change how medicine treats schizophrenia, epilepsy and other brain disorders.

30 Jul 2021

Researchers test a library of lipid-based compounds to enable safe delivery of RNA drugs to the lungs

Hokkaido University researchers in Japan created and tested a library of lipid-based compounds to find a way to safely and effectively deliver RNA drugs to the lungs.

30 Jul 2021

Amid covid booster debate, West Virginia to check immunity of vaccinated nursing home residents

West Virginia raced ahead of the country last winter to get people in nursing homes vaccinated against covid-19, but with cases and hospitalizations on the rise again, state officials want to know whether immunity levels are falling for residents who had their shots.

30 Jul 2021

BNT162b2 vaccine shows high efficacy at six months

The Pfizer/BioNTech vaccine appears to be highly effective in protecting against the SARS-CoV-2 infection, including its relatively resistant beta variant B.1.351.

30 Jul 2021

Laboratory News and Research

Next-Generation Sequencing and the Diagnosis of Disease

Biolabs LA at The Lundquist Institute reaches highly significant capacity milestone

Diagnosis of viral infections using micro and nanoscale technologies

Study shows COVID-19 organ-specific outcomes depend on anti-spike glycoprotein antibodies

Comprehensive review: Nanomaterial-based delivery vehicles for cancer vaccine development

PROTEIN-ID project aims to develop a device able to generate identity card of proteins

Open-access database could speed up repurposing of old drugs as new treatments

NSF awards $441,028 to address the workforce needs of regenerative medicine

Study conducts systematic review of the pre- and asymptomatic SARS-CoV-2 transmission

New breath test to tailor the dosage of drugs administered to epileptic patients

CDC scientists model the most efficient physical barrier against SARS-CoV-2 for worker protection

Antibiotic-resistant salmonella bacteria packs a punch for U.S. travelers

Existing drug may be effective in treating SARS-CoV-2

New discovery could pave the way towards therapeutic treatments for many cancers

UT Southwestern discovers the Achilles’ heel in ovarian cancers and potential biomarkers

New collaboration aims to boost vaccines manufacturing capability in South Africa

New understanding of the brain’s relay station could change medical treatment for brain disorders

Researchers test a library of lipid-based compounds to enable safe delivery of RNA drugs to the lungs

Amid covid booster debate, West Virginia to check immunity of vaccinated nursing home residents

BNT162b2 vaccine shows high efficacy at six months

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