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Antithrombotic endothelial dysfunction is prevented by Tie2 activation in severe COVID-19

Researchers from the US recently assessed if severe COVID-19 is linked to procoagulant dysfunction of the endothelium and changes in the Tie2-angiopoietin axis. They assessed circulating endothelial markers in a study cohort of 98 patients with mild, moderate, or severe COVID-19. This study is published on the medRxiv* preprint server.

19 May 2021

Working conditions and non-workplace factors affect COVID-19 mortality in England

Researchers from England recently estimated occupational variations in COVID-19 mortality in England and Wales during 2020 and examined how these differences changed post adjustment for non-workplace factors.

19 May 2021

Human monoclonal antibodies neutralize SARS-CoV-2 in an Fc-independent manner

Researchers from Israel recently isolated a set of SARS-CoV-2 neutralizing monoclonal antibodies from blood samples of patients with severe COVID-19. They were the first to show that transgenic K18-hACE2 mice infected with lethal doses of SARS-CoV-2 can be fully protected by administering antibodies even 3 days after infection

19 May 2021

Study: Multiple combinations of activities reduced risk of early death by 30%

A new study from Columbia University and an international team of researchers identifies multiple ways to achieve the same health benefits from exercise--as long as the exercise "cocktail" includes plenty of light physical activity.

19 May 2021

Toll-like receptor 2 (TLR2) detects the SARS-CoV-2 envelope protein and generates inflammatory cytokines

Researchers at St Jude Children’s Research Hospital found that toll-like receptor 2 detects the SARS-CoV-2 envelope protein-producing inflammatory cytokines.

19 May 2021

Randomized clinical trials compare effects of coronary revascularization versus medical therapy alone

A rigorous meta-analysis of randomized clinical trials (RCTs) that compared the effects of medical therapies alone with medical therapies plus revascularization in patients with stable ischemic heart disease (SIHD) was presented at EuroPCR on May 18, 2021.

19 May 2021

Social interventions also prolong life in medical patients

New research from BYU published in PLOS Medicine found that providing medical patients with social support leads to an increased chance of survival and elongation of life.

19 May 2021

Despite high mortality rates, cancer screenings are low in Sub-Saharan Africa

According to the World Health Organization, cervical cancer is the fourth most common form of cancer affecting women worldwide, and those in developing countries face a higher risk of dying from it.

19 May 2021

SARS-CoV-2 mRNA vaccine PTX-COVID19-B safe and highly immunogenic in preclinical study

COVID-19, the coronavirus disease of 2019, is one of the worst pandemics in human history. It emerged in December 2019 and is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Nearly 164 million SARS-CoV-2 infections and 3.4 million deaths have been reported globally since the beginning of the pandemic, which is still raging in many countries.

18 May 2021

Robust T cell and humoral immune response to SARS-CoV-2 in patients with immunodeficiency

A study of immune-deficient adults and children has shown that patients who fail to respond positively to infections and vaccinations have robust humoral immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) structural proteins.

18 May 2021

Previous study has underestimated the true extent of racial disparities in COVID-19 deaths

More than a year into the pandemic, the disproportionate burden of COVID-19 among racial and ethnic minorities in the US has been well documented.

18 May 2021

Researchers identify specific influenza targets that could lead to universal flu vaccine for indigenous populations

Researchers have identified specific influenza targets that could be used to better protect Indigenous people from experiencing severe influenza disease through a universal, T cell-based vaccine.

18 May 2021

Study: No major difference in mortality between patients treated with drug-coated and non-drug-coated devices

Peripheral artery disease (PAD), or blockages in the arteries outside of the heart, affects more than 200 million people worldwide and 12.5 million people in the United States. Patients with this circulatory disorder may develop severe leg pain or unhealing wounds that require a minimally invasive revascularization procedure to open the blood vessels to improve blood flow.

18 May 2021

Stair-climbing routines provide cardiovascular and muscular benefits to heart patients

A team of McMaster University researchers who studied heart patients found that stair-climbing routines, whether vigorous or moderate, provide significant cardiovascular and muscular benefits.

18 May 2021

COVID-19 mRNA vaccines safe and effective for pregnant and breastfeeding women

The current coronavirus disease 2019 (COVID-19) pandemic has brought untold devastation in its wake, with its rapid and asymptomatic spread to hundreds of millions of people the world over. Vaccines have been hailed as the way out of this situation, and a dozen or so are being rolled out in many different countries.

18 May 2021

Researchers receive $4.5 million grant to improve quality of care for people with cardiovascular disease

Researchers from the University of Tennessee Health Science Center have received a $4.5 million grant over three years from the Agency for Healthcare Research and Quality (AHRQ) to lead a statewide network of primary care providers, health systems, and academic centers to identify, develop, and implement patient-centered approaches to improve quality of care and outcomes for people with cardiovascular disease.

18 May 2021

‘Kicking you when you’re down’: Many cancer patients pay dearly for parking

A leading group of scientists working in universities, research centres, and innovative companies across Belgium, Germany, Greece, Portugal, Spain, and Switzerland just initiated a groundbreaking project hoping to treat stroke once and for all. The project, given the code name “ANGIE”, is backed by EU funding. "European scientists started developin

17 May 2021

Mortality News and Research

Antithrombotic endothelial dysfunction is prevented by Tie2 activation in severe COVID-19

Working conditions and non-workplace factors affect COVID-19 mortality in England

Human monoclonal antibodies neutralize SARS-CoV-2 in an Fc-independent manner

Study: Multiple combinations of activities reduced risk of early death by 30%

Toll-like receptor 2 (TLR2) detects the SARS-CoV-2 envelope protein and generates inflammatory cytokines

Randomized clinical trials compare effects of coronary revascularization versus medical therapy alone

Social interventions also prolong life in medical patients

Despite high mortality rates, cancer screenings are low in Sub-Saharan Africa

SARS-CoV-2 mRNA vaccine PTX-COVID19-B safe and highly immunogenic in preclinical study

Robust T cell and humoral immune response to SARS-CoV-2 in patients with immunodeficiency

Previous study has underestimated the true extent of racial disparities in COVID-19 deaths

Researchers identify specific influenza targets that could lead to universal flu vaccine for indigenous populations

Study: No major difference in mortality between patients treated with drug-coated and non-drug-coated devices

Stair-climbing routines provide cardiovascular and muscular benefits to heart patients

COVID-19 mRNA vaccines safe and effective for pregnant and breastfeeding women

Researchers receive $4.5 million grant to improve quality of care for people with cardiovascular disease

‘Kicking you when you’re down’: Many cancer patients pay dearly for parking

Genomic study tracks the rise of multidrug resistant E.coli

Delaying second dose of covid-19 vaccine could result in lower mortality under certain conditions

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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