Small Molecules News and Research

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Improving ability to predict autism risk with few drops of blood

Within days of birth, a few drops of blood are collected from every newborn in California--and across the United States -- which are then stored on filter paper and screened for dozens of genetic and congenital disorders, such as phenylketonuria, an inherited metabolic disorder that can result in intellectual disability, seizures, heart and behavioral problems.

13 Feb 2020

Developing new approaches to fight against multi-resistant pathogens

Developing fundamentally new approaches against multi-resistant germs: This is the goal of the new Bavarian research network bayresq.net which started in January 2020.

9 Feb 2020

Re-engineered plant compound reduces morphine-seeking behaviors in mice

The abuse of prescription and illegal opioids, such as morphine and heroin, is a major problem in the U.S., with devastating public health, economic and social consequences.

5 Feb 2020

Yale researchers find way to reverse type-2 diabetes and liver fibrosis in mice

In a pair of related studies, a team of Yale researchers has found a way to reverse type-2 diabetes and liver fibrosis in mice and has shown that the underlying processes are conserved in humans.

4 Feb 2020

New way to classify pituitary tumors could lead to better diagnoses

Houston Methodist neurosurgeons and neuroscientists are looking at a new way to classify pituitary tumors that could lead to more precise and accurate diagnosing for patients in the future.

4 Feb 2020

Ludwig Cancer Research study develops a safer CAR-T therapy

A Ludwig Cancer Research study has devised a new type of chimeric antigen-receptor (CAR) T cell-;a family of promising immunotherapies for cancer- that can be switched on and off on demand.

3 Feb 2020

Scientists discover small molecule that may slow or stop Parkinson's disease progression

A collaboration between scientists at Rutgers University and Scripps Research led to the discovery of a small molecule that may slow down or stop the progression of Parkinson's disease.

30 Jan 2020

Link between autism and poor cognition

Autistic people are often brilliant, but they may also have poor cognitive skills. The relationship between autism and either condition, inside the brain, has been far from clear. However, now a new study shows that poor cognition in autism could be due to the influence of a small gene fragment.

29 Jan 2020

Novel nanoparticle eats away portions of plaques that cause heart attacks

Michigan State University and Stanford University scientists have invented a nanoparticle that eats away - from the inside out - portions of plaques that cause heart attacks.

27 Jan 2020

Scientists discover small molecule that may slow or stop Parkinson's progression

A collaboration between scientists at Rutgers University and The Scripps Research Institute led to the discovery of a small molecule that may slow down or stop the progression of Parkinson's disease.

23 Jan 2020

Scientists call for more effort to map the human exposome

An international team of researchers is calling for a large-scale effort to map the health effects of cumulative exposure to environmental components such as chemical pollutants.

23 Jan 2020

Study finds new strategies for developing cancer drug

After years of research on cell surface receptors called Frizzleds, researchers at Karolinska Institutet in Sweden provide the proof-of-principle that these receptors are druggable by small molecules. The results, which are published in the scientific journal Nature Communications, open for new strategies to treat different types of cancer.

21 Jan 2020

UT Southwestern study identifies new vulnerability in kidney tumors

A UT Southwestern researcher led a team that identified a new vulnerability in kidney tumors, the 10th most common cause of cancer death in men and women.

17 Jan 2020

A naturally occurring protein may be responsible for many benefits of exercise

Whether it be a brisk walk around the park or high intensity training at the gym, exercise does a body good. But what if you could harness the benefits of a good workout without ever moving a muscle?

13 Jan 2020

Common genetic defect in prostate cancer associated with worse prognosis

Like security screening to make sure nothing harmful makes its way into a crowded area, cells in the human body use checkpoints to control their growth and prevent harmful mutations from making their way into new cell populations and causing trouble.

9 Jan 2020

Pathios appoints Stuart Hughes as CEO and announces US$8.8M Series A financing round

Pathios Therapeutics Limited, an innovative biotech company focused on the development of first-in-class therapies for autoimmune diseases and cancer, today announced a US$8.8M Series A financing round with leading international healthcare investors Canaan and Australia’s Medical Research Commercialization Fund managed by Brandon Capital.

9 Jan 2020

Research project leverages big data to close the gap on cognitive decline and healthy aging

A new research project at the University of Arizona Center for Innovation in Brain Science will apply a big-data approach, using bioinformatics and computational modeling, to better understand the systems biology of Alzheimer's and other neurodegenerative diseases.

8 Jan 2020