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N gene target failure method effectively detects SARS-CoV-2 Omicron in clinical samples

In a new study, researchers demonstrated that a commercial real-time polymerase chain reaction (RT-PCR) assay rapidly detects the SARS-CoV-2 Omicron variant.

2 Feb 2022

The ability of individuals to cross-recognize the Omicron spike protein following vaccination or prior infection

Scientists studied the ability of T cells to react with the Omicron spike.

2 Feb 2022

Quantitative framework to investigate the dynamic mechanism of host immune response confronting SARS-CoV-2 infection

The authors highlight that they have created a quantitative framework that allows the dynamic mechanism of the immune response to SARS-CoV-2 to be properly investigated.

2 Feb 2022

Determining the limit of detection for SARS-CoV-2 Omicron variant using rapid antigen tests

In a new study, researchers examined the analytical sensitivity of three widely used rapid antigen tests used in the USA to detect the SARS-CoV-2 Omicron variant, compared with the WA1 strain.

2 Feb 2022

Impact of equitable access to COVID-19 vaccines for all countries

In a new study, a team of researchers proposed a metapopulation model to assess the different SARS-CoV-2 vaccine allocation strategies adopted globally.

2 Feb 2022

Assessing an intranasal lentiviral booster against COVID-19 variants

A new study explores the possibility of vaccination via nasal route utilizing a lentiviral vaccination vector (LV) to be administered as a booster dose against COVID-19.

2 Feb 2022

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Researchers from China summarized the representative structures of SARS-CoV-2 proteins and discussed the development of novel therapeutic agents for targeting these proteins to treat and prevent COVID-19.

2 Feb 2022

Novel approach to improve intranasal sprays used to treat respiratory viral infections

Researchers proposed a novel approach to improve intranasal sprays used to treat respiratory viral infections, including SARS-CoV-2 infections.

2 Feb 2022

Rapid dominance of Omicron following its introduction to three Massachusetts universities

Researchers from the United States assessed the rapid dominance of the SARS-CoV-2 Omicron variant in three highly vaccinated Massachusetts university populations.

2 Feb 2022

Study reveals pet hamsters can acquire SARS-CoV-2 infection in real-life settings and transmit the virus back to humans

Researchers investigated the transmission of the SARS-CoV-2 Delta VOC from infected hamsters to humans.

2 Feb 2022

Study proposes Omicron variant may be derived from recombination of two early SARS-CoV-2 PANGO lineages

A recent study showed that the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron variant is a chimera of two earlier PANGO lineages of SARS-CoV-2.

2 Feb 2022

A mixed-effects deep learning model to diagnose COVID-19 from computed tomography imaging

Using best practice guidelines, they developed a mixed-effects deep learning model to classify images as healthy or COVID-19 accurately.

2 Feb 2022

New nanoparticle SARS-CoV-2 vaccine shows stronger, broader, and more durable protection

The first generation of COVID-19 vaccines have been highly effective, but also have limitations: their efficacy can wane without a booster shot, and they may be less effective against some variants.

2 Feb 2022

Research supports the need for a 3rd mRNA COVID vaccine in patients taking immunosuppressants

New research posted to the medRxiv* preprint server finds patients with immune-mediated inflammatory diseases undergoing anti-TNF therapy had the greatest reduction of antibody levels three months after vaccination. In addition, they had weaker neutralization responses towards severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern.

1 Feb 2022

Scientists develop platform to track SARS-CoV-2 lineages

A team of researchers led by Laura D. Hughes from The Scripps Research Institute in California created an online platform called Outbreak.info to track over 40 million lineages and SARS-CoV-2 mutation across 7,000 locations.

1 Feb 2022

COVID-19 vaccines induce robust cellular immune response against SARS-CoV-2 Omicron

A team of scientists from the United States has recently demonstrated that current coronavirus disease 2019 (COVID-19) vaccines induce robust spike-specific T cell responses against the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

1 Feb 2022

Study confirms SARS-CoV-2 Omicron variant has a decreased ability to enter lung cells

A large multinational group of researchers has shown how the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has gained exceptional immune evasion properties but also a much lower propensity to enter cells such as those in lung alveoli, resulting in its reduced pathogenicity. Their paper is currently released as an unedited version of the manuscript prior to publication in the journal Nature.

1 Feb 2022

Study demonstrates substantial immune response in individuals infected with SARS-CoV-2 Omicron variant

Researchers analyze neutralizing antibodies against the SARS-CoV-2 VOCs with the sera of vaccinated individuals infected with the Omicron variant.

1 Feb 2022

Developing post-vaccination SARS-CoV-2 standard reference sera

A new study reports the generation of reference sera reagents that were obtained from subjects vaccinated with one of four COVID-19 vaccines.

1 Feb 2022

Study: COVID-19 infections tend to be milder in fully vaccinated patients

The clinical and imaging characteristics of COVID-19 breakthrough infections in fully vaccinated patients tend to be milder than those of partially vaccinated or unvaccinated patients, according to a new multicenter study published in the journal Radiology.

1 Feb 2022

SARS News and Research

N gene target failure method effectively detects SARS-CoV-2 Omicron in clinical samples

The ability of individuals to cross-recognize the Omicron spike protein following vaccination or prior infection

Quantitative framework to investigate the dynamic mechanism of host immune response confronting SARS-CoV-2 infection

Determining the limit of detection for SARS-CoV-2 Omicron variant using rapid antigen tests

Impact of equitable access to COVID-19 vaccines for all countries

Assessing an intranasal lentiviral booster against COVID-19 variants

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Novel approach to improve intranasal sprays used to treat respiratory viral infections

Rapid dominance of Omicron following its introduction to three Massachusetts universities

Study reveals pet hamsters can acquire SARS-CoV-2 infection in real-life settings and transmit the virus back to humans

Study proposes Omicron variant may be derived from recombination of two early SARS-CoV-2 PANGO lineages

A mixed-effects deep learning model to diagnose COVID-19 from computed tomography imaging

New nanoparticle SARS-CoV-2 vaccine shows stronger, broader, and more durable protection

Research supports the need for a 3rd mRNA COVID vaccine in patients taking immunosuppressants

Scientists develop platform to track SARS-CoV-2 lineages

COVID-19 vaccines induce robust cellular immune response against SARS-CoV-2 Omicron

Study confirms SARS-CoV-2 Omicron variant has a decreased ability to enter lung cells

Study demonstrates substantial immune response in individuals infected with SARS-CoV-2 Omicron variant

Developing post-vaccination SARS-CoV-2 standard reference sera

Study: COVID-19 infections tend to be milder in fully vaccinated patients

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