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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Coronavirus has mutated into at least 30 variants

The coronavirus disease (COVID-19) continues to threaten millions of people across the globe, and lockdowns appear set to remain in place in many countries amid rising death tolls, as governments decide whether to extend restrictions aimed at reducing the spread of the virus. Now, a new study reveals that the novel coronavirus has mutated into at least 30 different genetic variants, affecting different parts of the world.

22 Apr 2020

Study creates a new platform to study single-cell genomics of many diseases

Although advances in genetics and genomics reveal numerous disease-associated gene mutations, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual disease-causing processes.

22 Apr 2020

Emergex partners with George Mason University for highly pathogenic RNA virus studies

Emergex Vaccines Holding Limited, a biotechnology company developing CD8+ priming set-point vaccines to prevent serious infectious diseases, today announced that it has entered into an agreement with the George Mason University, based in Virginia, in the United States.

22 Apr 2020

Risk prediction model identifies people at higher risk of pancreatic cancer

Bottom Line: A risk prediction model that combined genetic and clinical factors with circulating biomarkers identified people at significantly higher than normal risk of pancreatic cancer.

22 Apr 2020

The Latest Electron Paramagnetic Resonance (EPR) Spectroscopy Technology

In this interview, Kalina Ranguelova, Senior EPR Application Scientist at Bruker BioSpin, discusses the newest member of benchtop EPS spectrometers family, the Magnettech ESR 5000.

From Bruker BioSpin - NMR, EPR and Imaging 22 Apr 2020

Scientists find gene signature for poor response to standard therapy in rare uterine cancer

Women who don't survive a rare and aggressive uterine cancer called uterine serous carcinoma, have high expression of a group of 73 genes, a score scientists say can help identify these women and improve their outcome.

22 Apr 2020

Radiation therapy plays a crucial role in management of OPSCC

HPV-negative UM-SCC4 with and without transfection of HPV E6 oncoprotein, HPV-negative UPCI-SCC-089, and HPV-positive UPCI-SCC-099 cell lines were used in this study.

22 Apr 2020

Study reveals surprising findings on gene involved in human pregnancy

From an evolutionary perspective, human pregnancy is quite strange, says University at Buffalo biologist Vincent Lynch.

22 Apr 2020

Research: Peptide makes older antibiotics effective again at doses 100 times lower than usual

A peptide renders older antibiotics effective again at doses 100 times lower than the common dosage, as shown by research from örebro University.

22 Apr 2020

Immunity to coronavirus infection may help stem the pandemic

The raging coronavirus pandemic is causing immense fear and uncertainty across the world. One of the most distressing aspects of COVID-19 disease is the seemingly large number of unknowns. These include the burning question of immunity. Does a person who was sick with the COVID-19 and then recovered or was infected without symptoms, have immunity against re-infection?

21 Apr 2020

Age-related DNA modifications linked with susceptibility to eye disease

National Eye Institute researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression.

21 Apr 2020

New study may offer a breakthrough in treating telomere diseases

Capping decades of research, a new study may offer a breakthrough in treating dyskeratosis congenita and other so-called telomere diseases, in which cells age prematurely.

21 Apr 2020

CRISPR helps identify new protein potentially involved in Alzheimer’s disease

Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "molecular scissors" of CRISPR/Cas9 to search for new genes related to the neurodegenerative disease.

21 Apr 2020

A new, potential treatment for nonalcoholic steatohepatitis with fibrosis

In the 2020 April 21 issue of Journal of Hepatology, a research group from the Department of Hepatology in Osaka City University Graduate School of Medicine, Japan reported that a new insight into the pathophysiology of human nonalcoholic steatohepatitis (NASH) with fibrosis and suggested a possibility of the new therapy using cytoglobin (CYGB) inducer for clinical application.

21 Apr 2020

NEI researchers link age-related DNA modifications to susceptibility to eye disease

Researchers profiling epigenomic changes in mouse photoreceptors suggest that age-related eye diseases may be linked to gene expression.

21 Apr 2020

Experts identify new protein that leads to Alzheimer’s disease

Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease.

21 Apr 2020

A promising method to diagnose sepsis with high accuracy

Whether activating or silencing genes, breaking down defective cells or building new tissue, our body is constantly working to repair itself, even in cases of illness.

21 Apr 2020

A new biosensor to quickly and reliably detect novel coronavirus

Jing Wang and his team at Empa and ETH Zurich usually work on measuring, analyzing and reducing airborne pollutants such as aerosols and artificially produced nanoparticles.

21 Apr 2020

Advanced paternal age associated with risk of neurodevelopmental disorders in children

It is no secret that genetic factors play a role in determining whether children have neurodevelopmental disorders. Maternal exposure to drugs and viral or bacterial illnesses can be detrimental too.

21 Apr 2020

CRISPR technology mobilized for rapid COVID-19 diagnosis

A group of authors from the United States published a study in the scientific journal Nature Biotechnology in which they have described a CRISPR-Cas-based approach for rapid and accurate diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection – without the need for complex laboratory infrastructure.

20 Apr 2020