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New "masked" version of immunotherapy could help fight cancer without causing side effects

Many cancer treatments are notoriously savage on the body; they attack healthy cells at the same time as tumor cells, causing a plethora of side effects.

1 Jun 2022

Black patients with early-onset colorectal cancer receive worse, less timely care than white counterparts

In a new large national study led by researchers at the American Cancer Society, Black patients diagnosed with early-onset colorectal cancer received worse and less timely care than their white counterparts.

31 May 2022

Her first colonoscopy cost her $0. Her second cost $2,185. Why?

Elizabeth Melville and her husband are gradually hiking all 48 mountain peaks that top 4,000 feet in New Hampshire.

31 May 2022

Interactive web portal details the extent of splicing events in noncoding sequences

An online tool reveals the extent of gene-restructuring events in noncoding sequences.

30 May 2022

Medical cannabis use shown to improve cancer-related symptoms in new study

Researchers describe the effectiveness and safety of medical cannabis use for treating cancer-related symptoms.

30 May 2022

Study: Most clinicians do not follow recommendations against prescribing antibiotics for asymptomatic bacteriuria

An estimated 70 percent of primary care physicians reported in a survey that they would still prescribe antibiotics to treat asymptomatic infections based solely on a positive urine specimen.

27 May 2022

Betting on ‘golden age’ of colonoscopies, private equity invests in gastro docs

Mariel needed a new gastroenterologist. Having just moved back to San Antonio, the 30-something searched for a doctor to manage her Crohn's disease, an inflammatory bowel condition that is successfully managed with medications and lifelong monitoring — including regular colonoscopies.

27 May 2022

Use of computer-aided technology during colonoscopy increases adenoma detection rate

Colonoscopies performed with computer-aided detection, or artificial intelligence, (AI) saw an increase in the overall rate of detection of adenoma, or cancerous and precancerous polyps, by 27 percent in average-risk patients, according to new data presented today at the Digestive Disease Week Annual Meeting.

24 May 2022

New analysis finds persistent racial, ethnic disparities in survival rates for early-onset colon cancer

Five-year survival for younger adults with colorectal cancer (CRC) improved only for Whites between 1992 and 2013, according to a new analysis to be presented at Digestive Disease Week 2022.

24 May 2022

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute have identified a new molecular drug target that could result in new cancer drugs with fewer side effects.

20 May 2022

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Investigators from Rutgers Cancer Institute of New Jersey, New Jersey's only National Cancer Institute- Designated Comprehensive Cancer Center, led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens including microsatellite-stable and unstable (MSI) tumors.

19 May 2022

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Imugene Limited, a clinical stage immuno-oncology company, and City of Hope, one of the largest cancer research and treatment organizations in the United States, today announced that the first patient was dosed in a Phase 1 clinical trial evaluating the safety of novel cancer-killing virus CF33-hNIS VAXINIA when used in people with advanced solid tumors.

18 May 2022

Why do diabetic patients have more severe SARS-CoV-2 infections?

A recent study published in the journal Cell Metabolism illustrated the function of angiotensin-converting enzyme 2 (ACE2) in renal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among diabetic patients.

16 May 2022

Researchers discover new gene that confers resistance to prostate cancer treatment

Northwestern Medicine investigators have identified a gene that confers resistance to a common prostate cancer treatment, according to a study published in Cancer Research.

13 May 2022

Tumors release lactate to force neighboring cells into supporting cancer growth

Tumors can force neighboring cells into supporting cancer growth by releasing lactate into their local environment, according to researchers at Weill Cornell Medicine.

10 May 2022

Study identifies interleukin-6 as a potential target in refining cancer therapies

Immune checkpoint inhibitors have revolutionized the treatment of many cancers by using our body's immune system to kill cancer.

9 May 2022

Discovery provides critical clues to why many immunotherapies trigger dangerous side effects

It's not often that a failed clinical trial leads to a scientific breakthrough. When patients in the UK started showing adverse side effects during a cancer immunotherapy trial, researchers at La Jolla Institute for Immunology (LJI) Center for Cancer Immunotherapy and University of Liverpool went back through the data and worked with patient samples to see what went wrong.

5 May 2022

Study investigates stress granule formation during infection with the human common cold coronavirus and SARS-CoV-2

Researchers analyzed the inhibition of stress granules formation in cells infected by the human common cold coronavirus HCOV-OC43 and SARS-CoV-2.

5 May 2022

Research suggests Twitter as a powerful tool to drive awareness about pancreatic cancer

A new study investigating pancreatic cancer-related Twitter conversations has found high rates of engagement among patients, advocates, and non-healthcare related individuals active in the pancreatic cancer space.

5 May 2022

Hydrogen sulfide production in the gut is based on animal- or plant-based diet, study finds

Published in Clinical Nutrition, researchers from the University of Minnesota Medical School looked at colonic hydrogen sulfide -; a toxic gas in the body that smells like rotten eggs -; production in people in response to animal- and plant-based diet interventions.

4 May 2022

Colon News and Research

New "masked" version of immunotherapy could help fight cancer without causing side effects

Black patients with early-onset colorectal cancer receive worse, less timely care than white counterparts

Her first colonoscopy cost her $0. Her second cost $2,185. Why?

Interactive web portal details the extent of splicing events in noncoding sequences

Medical cannabis use shown to improve cancer-related symptoms in new study

Study: Most clinicians do not follow recommendations against prescribing antibiotics for asymptomatic bacteriuria

Betting on ‘golden age’ of colonoscopies, private equity invests in gastro docs

Use of computer-aided technology during colonoscopy increases adenoma detection rate

New analysis finds persistent racial, ethnic disparities in survival rates for early-onset colon cancer

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Why do diabetic patients have more severe SARS-CoV-2 infections?

Researchers discover new gene that confers resistance to prostate cancer treatment

Tumors release lactate to force neighboring cells into supporting cancer growth

Study identifies interleukin-6 as a potential target in refining cancer therapies

Discovery provides critical clues to why many immunotherapies trigger dangerous side effects

Study investigates stress granule formation during infection with the human common cold coronavirus and SARS-CoV-2

Research suggests Twitter as a powerful tool to drive awareness about pancreatic cancer

Hydrogen sulfide production in the gut is based on animal- or plant-based diet, study finds

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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