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Novel, rapid and efficient assay for SARS-CoV-2 neutralizing antibodies

Researchers validate a quick, highly efficient, and automated assay to detect neutralizing antibodies against SARS-CoV-2.

7 Feb 2022

Fever the dominant symptom in SARS-CoV-2 Alpha- and Delta-infected children

Researchers assess the different clinical symptoms of SARS-CoV-2 infection in children and adolescents across different time periods.

7 Feb 2022

mRNA-based COVID-19 booster vaccination shown to protect against severe omicron infection in macaques

Scientists recently evaluated the effectiveness of a booster dose of the Moderna-developed COVID-19 vaccine and omicron spike-specific mRNA vaccine in non-human primates that are primed with the Moderna vaccine.

7 Feb 2022

Colchicine holds promise to reduce the risk of severe COVID-19

A recent article, published in Rheumatology and Therapy, reviews the potent evidence of colchicine against the SARS-CoV-2 infection.

7 Feb 2022

Investigating the immunology of COVID-19 infected children

Researchers published a new study that focused on the key principles of developmental immunology associated with immunobiology and the clinical impacts of COVID-19 infections in children and adults.

7 Feb 2022

Omicron sequences containing Delta mutation detected during SARS-CoV-2 genomic surveillance

This research letter published in Emerging Infectious Diseases warns scientists to interpret unusual mutations with caution.

7 Feb 2022

Evolutionary history of ACE2 binding across a diverse range of sarbecoviruses and ACE2 orthologs

Researchers have been investigating sarbecovirus lineages and the ability of those lineages to evolve the ability to bind ACE2.

7 Feb 2022

Study explores omicron-reactive T- and B- cell responses in COVID-19 vaccine recipients

A new study analyzes neutralizing antibodies and T-cell responses targeting the SARS-CoV-2 D614G, as well as some variants of concern.

7 Feb 2022

Study links COVID-19 inflammatory manifestations in brain lysates to Alzheimer’s Disease markers

In a new study, researchers investigated a link between the body’s inflammatory response to SARS-CoV-2 infection within the neuropathological pathways and tau hyperphosphorylation.

7 Feb 2022

Innate immune processes involved in SARS-CoV-2 recognition and resultant inflammation

A new article reviewed the innate immune detection and signaling pathways that the host uses against SARS-CoV-2.

7 Feb 2022

Study investigates if prior SARS-CoV-2 infection increases sensitivity to toxin that induces parkinsonism

A recent study explored whether individuals who have recovered from mild to moderate or severe COVID-19 may have an increased risk for developing Parkinson’s disease in the future.

7 Feb 2022

Cerebrovascular impairment persists months after severe acute COVID-19, UK study

Researchers in the United Kingdom have conducted an observational cohort study on hospitalized patients and have found that the degree of severity of acute coronavirus disease 2019 (COVID-19) predicts the occurrence of chronic cerebrovascular impairment. The study further suggests that the levels of cerebrovascular impairment are associated with worse cognitive, mental, and physical well-being.

7 Feb 2022

USP22 crucial for type III interferon signaling and SARS-CoV-2 infection

In a recent study posted to the bioRxiv* pre-print server, a team of researchers demonstrated that ubiquitin-specific peptidase 22 (USP22) is a crucial regulator of basal interferon (IFN) signaling in native human intestinal epithelial cells (hIECs).

7 Feb 2022

Study looks at rapid antigen vs. PCR tests in the emergency department triage

In a recent study posted to the Lancet preprint* server, researchers assessed the utility of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) rapid antigen testing (RAT) for patient triage in the hospital emergency department (ED).

7 Feb 2022

Booster vaccines found to augment T-cell responses to SARS-CoV-2 Omicron

In a recent study published in the latest issue of the journal Cell, a team of researchers evaluated T-cell reactivity to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant's spike (S) and non-spike proteins.

6 Feb 2022

Sentinel cards found to be effective for indoor SARS-CoV-2 monitoring

In a recent study posted to the bioRxiv* preprint server, a team of researchers used sentinel cards for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) monitoring in schools where individual-level sampling is tedious due to privacy or compliance reasons and higher cost.

6 Feb 2022

Vaccine-induced immunity and prior infection effective in reducing COVID severity in reinfections

A recent study posted to the Research Square* preprint server and under consideration for inclusion in the journal Scientific Reports assessed the epidemiology of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) reinfections.

6 Feb 2022

A novel approach to predict mutations within the SARS-CoV-2 spike

A study posted recently to the bioRxiv* preprint server demonstrated that the emergence of new spike variants of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can be predicted.

6 Feb 2022

Detection of SARS-CoV-2 Delta variant infection in a domestic cat

The first published case describing the Delta variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a domestic cat in the United States highlights the realistic scenario of spillover infections with emerging viral variants that threaten human and animal health.

6 Feb 2022

Assessing public trust and understanding of CDC’s revised COVID-19 guidelines

Researchers assess the understanding and trust of the revised COVID-19 isolation and quarantine guidance recommended by the U.S. CDC.

6 Feb 2022

Syndrome News and Research

Novel, rapid and efficient assay for SARS-CoV-2 neutralizing antibodies

Fever the dominant symptom in SARS-CoV-2 Alpha- and Delta-infected children

mRNA-based COVID-19 booster vaccination shown to protect against severe omicron infection in macaques

Colchicine holds promise to reduce the risk of severe COVID-19

Investigating the immunology of COVID-19 infected children

Omicron sequences containing Delta mutation detected during SARS-CoV-2 genomic surveillance

Evolutionary history of ACE2 binding across a diverse range of sarbecoviruses and ACE2 orthologs

Study explores omicron-reactive T- and B- cell responses in COVID-19 vaccine recipients

Study links COVID-19 inflammatory manifestations in brain lysates to Alzheimer’s Disease markers

Innate immune processes involved in SARS-CoV-2 recognition and resultant inflammation

Study investigates if prior SARS-CoV-2 infection increases sensitivity to toxin that induces parkinsonism

Cerebrovascular impairment persists months after severe acute COVID-19, UK study

USP22 crucial for type III interferon signaling and SARS-CoV-2 infection

Study looks at rapid antigen vs. PCR tests in the emergency department triage

Booster vaccines found to augment T-cell responses to SARS-CoV-2 Omicron

Sentinel cards found to be effective for indoor SARS-CoV-2 monitoring

Vaccine-induced immunity and prior infection effective in reducing COVID severity in reinfections

A novel approach to predict mutations within the SARS-CoV-2 spike

Detection of SARS-CoV-2 Delta variant infection in a domestic cat

Assessing public trust and understanding of CDC’s revised COVID-19 guidelines

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