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Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea.

8 Apr 2022

Researchers demonstrate how a narrow-spectrum antibiotic selectively targets C. diff

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.

6 Apr 2022

HIV drug stops disease progression in 25% of patients with fourth-line metastatic colorectal cancer

New clinical research shows that lamivudine, a reverse transcriptase inhibitor widely used in HIV therapy, stopped disease progression in 25% of patients with fourth-line metastatic colorectal cancer.

5 Apr 2022

Study highlights racial disparities among gastrointestinal cancer patients undergoing surgery

African-American adult patients are more likely than white patients to receive substandard gastrointestinal cancer surgery, according a large study led by researchers at Yale Cancer Center. The findings are reported today in the journal JAMA Network Open.

4 Apr 2022

Study analyzed several naturally-occurring amino acid variations found in the extended loop harboring the SARS-CoV-2 S1/S2 cleavage site

A recent study analyzed the polymorphisms in the SARS-CoV-2 spike proteins' S1/S2 subunits.

30 Mar 2022

Novel drug combination can boost chemoimmunotherapy response in bladder cancer patients

Adding an anti-inflammatory medication to immunotherapy and standard chemotherapy drugs may provide long-term suppression of aggressive bladder tumor growth, according to a proof-of-concept study led by Cedars-Sinai Cancer investigators.

28 Mar 2022

Flinders research uncovers how enteric nervous system in the gut communicates with the brain

How the ‘second brain’ – the enteric nervous system in our gut – communicates with our first brain has been one of the most challenging questions faced by enteric neuroscientists, until now.

26 Mar 2022

Predicting the risk of some common diseases in preimplantation fertilized embryos

A new study uses a novel strategy for whole-genome reconstruction by using parental genome sequencing and sibling embryo genotyping.

23 Mar 2022

TTUHSC researcher secures $1.9 million grant to investigate vulnerabilities in ALT cancers

The National Cancer Institute, part of the National Institutes of Health, recently awarded a five-year, $ $1.9 million grant to C. Patrick Reynolds, M.D., Ph.D., director for the School of Medicine Cancer Center at the Texas Tech University Health Sciences Center.

23 Mar 2022

New approach could lead to quicker generation of effective, personalized cancer vaccines

Scientists have created a pipeline for identifying, prioritizing and evaluating potential tumor antigens for the fast generation of cancer vaccines, according to a report published today in eLife.

22 Mar 2022

Novel screening platform flags 95% of stage 1 cancers

A novel screening platform has flagged more than 95 percent of stage 1 cancers, according to a pilot study published in Nature Communications Medicine. If validated by future studies, the approach offers a new way to detect the third-leading cause of U.S. cancer deaths in 2020.

21 Mar 2022

Mayo Clinic researchers report differences in genomic data quality among racial groups

Mayo Clinic researchers studied the differences in genomic data quality among racial groups in one of the largest and most widely used cancer research datasets, The Cancer Genome Atlas.

17 Mar 2022

Toxin-producing yeast strains may damage the gut of patients with inflammatory bowel disease

Individual Candida albicans yeast strains in the human gut are as different from each other as the humans that carry them, and some C. albicans strains may damage the gut of patients with inflammatory bowel disease (IBD), according to a new study from researchers at Weill Cornell Medicine.

16 Mar 2022

Colon News and Research

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Researchers demonstrate how a narrow-spectrum antibiotic selectively targets C. diff

HIV drug stops disease progression in 25% of patients with fourth-line metastatic colorectal cancer

Study highlights racial disparities among gastrointestinal cancer patients undergoing surgery

Study analyzed several naturally-occurring amino acid variations found in the extended loop harboring the SARS-CoV-2 S1/S2 cleavage site

Novel drug combination can boost chemoimmunotherapy response in bladder cancer patients

Flinders research uncovers how enteric nervous system in the gut communicates with the brain

Predicting the risk of some common diseases in preimplantation fertilized embryos

TTUHSC researcher secures $1.9 million grant to investigate vulnerabilities in ALT cancers

New approach could lead to quicker generation of effective, personalized cancer vaccines

Novel screening platform flags 95% of stage 1 cancers

Mayo Clinic researchers report differences in genomic data quality among racial groups

Toxin-producing yeast strains may damage the gut of patients with inflammatory bowel disease

New computational biology method deciphers gut microbiome ‘chatter’ to fight IBD

Older female cancer survivors face challenges with physical activity due to chronic lower extremity lymphedema

'Post-apoptotic pro-metastatic cells' appear to be potential metastasis prevention targets

'Dual eligible' patients may have poorer outcomes, higher spending even in the highest-quality hospitals

Active compound in Chinese herbs prevents colon cancer in mice

NCCN publishes new resources for treating rare tumor types

New fluorescent label provides a clearer picture of how DNA architecture is disrupted in cancer cells

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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