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Stage IIIB NSCLC patients may benefit from surgical resection in combination with chemo or radiation therapy

Patients diagnosed with an advanced form of metastatic non-small cell lung cancer (NSCLC) may benefit from surgical resection (removal of all or part of the lung) in combination with chemotherapy and radiation therapy, according to an article in the June 2015 issue of The Annals of Thoracic Surgery.

11 Jun 2015

Surgical resection, chemo and radiation therapy combination may help treat metastatic lung cancer

10 Jun 2015

BerGenBio begins BGB324 Phase 1b trial in combination with erlotinib in NSCLC patients

BerGenBio AS, an oncology biopharmaceutical company, today announces that its multi-centre open label Phase 1b trial (BGBC004) of BGB324, a selective inhibitor of Axl, in patients with Stage IIIb and Stage IV non-small cell lung cancer (NSCLC) in erlotinib-sensitive and refractory patients who have an activating EGFR mutation, is now underway at the University of Texas MD Anderson Cancer Center, Houston, Oncology Partners, Houston, and at UT Southwestern Medical Center, Dallas, Texas, USA.

10 Jun 2015

Study examines effects of intravenous glutamine on hind limb ischemia reperfusion injury

A single dose of intravenous glutamine (GLN) administered immediately after a non-lethal lower limb ischemia reduces the reperfusion inflammatory reaction locally and systemically according to a new study.

10 Jun 2015

Detecting blood clots with a portable device

Blockages in lung arteries could be diagnosed safely in real-time helping as many as 20,000 respiratory patients in Australia each year with emerging technology being developed by electrical engineering researchers at the University of Sydney.

10 Jun 2015

Findings could lead to new therapies that stop breast cancer progression

Scientists have discovered a trigger that allows breast cancer cells to spread to the lungs. They have found that blocking the signals in mice with breast cancer greatly reduces the number of secondary tumours found in the lungs.

9 Jun 2015

Cell fusion triggers multiple genetic changes that convert normal cells to cancer cells

Although there is no one established universal cause of cancer, genetic changes are central to its development. The accumulation of spontaneous genetic changes, or mutations, that occur when cells divide can be hastened by exposure to carcinogens such as cigarette smoke (lung cancer) and infectious agents such as the papillomavirus (cervical cancer).

9 Jun 2015

Breathe NIOV System improves exercise duration among patients with chronic respiratory disease

Breathe Technologies, a developer and manufacturer of innovative medical technologies for patients with respiratory insufficiency diseases and neuromuscular diseases, announced new data today demonstrating that use of its Non-Invasive Open Ventilation (NIOV) System in pulmonary rehabilitation was associated with significant improvement in mean exercise duration change (approximately 63 percent) among patients with chronic respiratory disease.

8 Jun 2015

Clinical data of Trovagene's Precision Cancer Monitoring platform to be presented at two medical conferences

Trovagene, Inc., a developer of cell-free molecular diagnostics, announced today that clinical data featuring its Precision Cancer MonitoringSM platform will be presented at the 2015 Cancer Markers and Liquid Biopsies conference in San Diego, CA on June 11-12, and at the AACR Precision Medicine Series: Integrating Clinical Genomics and Cancer Therapy in Salt Lake City, UT on June 13-16.

8 Jun 2015

Celtaxsys closes $40M Series D financing and receives $5M CFFT grant to conduct CTX-4430 Phase 2 trial

Celtaxsys, Inc., a clinical stage drug development company focused on developing novel therapies for inflammatory diseases, today announced the successful completion of a $40M Series D financing led by Domain Partners VIII. Additional investors in the financing include Lumira Capital, RMI Partners, Masters Capital Management and the Georgia Research Alliance Venture Fund.

8 Jun 2015

New therapeutic target discovered for idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease for which as yet no causal therapy exists. It is, however, known that the lung interstitium - the connective tissue between the air sacs in the lower part of the lung - is affected.

8 Jun 2015

St. Michael's Hospital researchers find novel method to combat flu virus

The flu kills hundreds of thousands of people around the world every year, yet there is essentially only one class of drugs to fight the ever-changing virus. Cases of flu resistant to this class of drugs have already been reported and researchers worry a completely new strain of flu could evolve, leading to a pandemic like the one in 1918 that killed approximately 50 million people.

8 Jun 2015

University at Albany researcher receives $1.76 million NIH grant to explore role of vitamin D in breast cancer

Each year, about 230,000 new cases of breast cancer are diagnosed in women in the U.S. It remains the third leading cause of death, behind only heart disease and lung cancer. Of the new cases, about 20 percent of women will be diagnosed with "triple negative" breast cancer (TNBC), a deadly form of breast cancer that does not respond to standard treatments such as tamoxifen or aromatase inhibitors.

7 Jun 2015

Death rates are higher in zip codes with more fine particulate air pollution

A new study by researchers at Harvard T.H. Chan School of Public Health found that death rates among people over 65 are higher in zip codes with more fine particulate air pollution (PM2.5) than in those with lower levels of PM2.5.

5 Jun 2015

Physicians at UH Case Medical Center implant revolutionary device to treat right ventricular heart disease

University Hospitals Case Medical Center physicians in the Harrington Heart & Vascular Institute were the first in the state of Ohio to implant a revolutionary device to treat right ventricular heart disease.

5 Jun 2015

Volunteer double act are ‘still game’ after 10 years

The Golden Jubilee’s very own ‘Jack and Victor’ have been honoured for serving Scotland’s national hospital for over a decade.

5 Jun 2015

Experimental Zephyr endobronchial valve provides good result in emphysema patient at UAB

In late March, physicians at the University of Alabama at Birmingham carefully threaded a one-way valve the size of a black-eyed pea into the lower lobe of Dennis Bullock's left lung. Bullock, a 67-year-old emphysema patient, was the fourth person at UAB to receive the experimental Zephyr endobronchial valve.

4 Jun 2015

New strategy involving three-pronged approach may keep lung cancer aside

Lung cancer is the leading cause of cancer death worldwide, responsible for some 1.59 million deaths a year. That figure is due, in part, to the fact that lung cancer often returns after what seems at first to be successful treatment. However, the recurring cancer is often resistant to the chemotherapy and other drugs that originally drove it into remission.

4 Jun 2015

Wistar Institute scientists find new biomarker that appears to be more accurate at detecting NSCLC

Survival rates for patients with lung cancer increase dramatically the earlier the disease is diagnosed, underscoring the need for effective biomarkers that can be used for detection. Now, scientists at The Wistar Institute have found a protein that circulates in the blood that appears to be more accurate at detecting non-small cell lung cancer (NSCLC) than currently available methods used for screening.

4 Jun 2015

New research draws on support from patients and public to investigate impact of cardiac surgery

A University of Leicester-based research group funded by the British Heart Foundation is drawing on support from patients and members of the public to investigate why cardiac surgery can often result in serious or fatal damage to other organs in the body.

3 Jun 2015

Lungs News and Research

Stage IIIB NSCLC patients may benefit from surgical resection in combination with chemo or radiation therapy

Surgical resection, chemo and radiation therapy combination may help treat metastatic lung cancer

BerGenBio begins BGB324 Phase 1b trial in combination with erlotinib in NSCLC patients

Study examines effects of intravenous glutamine on hind limb ischemia reperfusion injury

Detecting blood clots with a portable device

Findings could lead to new therapies that stop breast cancer progression

Cell fusion triggers multiple genetic changes that convert normal cells to cancer cells

Breathe NIOV System improves exercise duration among patients with chronic respiratory disease

Clinical data of Trovagene's Precision Cancer Monitoring platform to be presented at two medical conferences

Celtaxsys closes $40M Series D financing and receives $5M CFFT grant to conduct CTX-4430 Phase 2 trial

New therapeutic target discovered for idiopathic pulmonary fibrosis

St. Michael's Hospital researchers find novel method to combat flu virus

University at Albany researcher receives $1.76 million NIH grant to explore role of vitamin D in breast cancer

Death rates are higher in zip codes with more fine particulate air pollution

Physicians at UH Case Medical Center implant revolutionary device to treat right ventricular heart disease

Volunteer double act are ‘still game’ after 10 years

Experimental Zephyr endobronchial valve provides good result in emphysema patient at UAB

New strategy involving three-pronged approach may keep lung cancer aside

Wistar Institute scientists find new biomarker that appears to be more accurate at detecting NSCLC

New research draws on support from patients and public to investigate impact of cardiac surgery

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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