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Two doses of Moderna COVID-19 vaccine highly effective against all SARS-CoV-2 variants

Kaiser Permanente research published on December 15, 2021 in The British Medical Journal showed 2 doses of Moderna COVID-19 vaccine were highly effective against all SARS-CoV-2 variants; however, vaccine effectiveness against the delta variant moderately declined with increasing time after vaccination.

15 Dec 2021

Evaluation of SARS-CoV-2 neutralizing antibodies in mothers and infants

A new study assessed nAb activities against five strains of SARS-CoV-2 in paired maternal and infant cord blood samples.

15 Dec 2021

How SARS-CoV-2 affects the male reproductive system

Researchers review the potentially harmful consequences on the male reproductive system in COVID-19 patients.

15 Dec 2021

Evaluation of SARS-CoV-2 Omicron's immune evasion potential

Researchers use VSV vector and Omicron spike protein containing all 32 mutations to create the pseudotyped SARS-CoV-2 Omicron variant (PV-Omicron).

15 Dec 2021

Signatures of rising SARS-CoV-2 Delta infections in New York

Researchers estimate the probability of breakthrough infections by the Delta variant as compared to other variants.

15 Dec 2021

SARS-CoV-2 VOCs dependent on IFITM2 for efficient infection establishment

Researchers demonstrate that the Alpha, Beta, Gamma, and Delta variants of SARS-CoV-2 require endogenous IFITM2 expression for efficient replication.

15 Dec 2021

New Canadian study shows how SARS-CoV-2 transmission occurred in schools

Researchers explore the frequency, cluster size, and transmission rate of COVID-19 in schools using a simple mathematical model.

15 Dec 2021

Weak T-cell clonal response to SARS-CoV-2 vaccination in IBD patients deficient in antibody-responders

Researchers investigate the post-vaccination clonal T-cell response and its relationship to antibody responses in IBD patients.

15 Dec 2021

CDC researchers analyze the earliest batch of COVID-19 tests

The earliest batch of COVID-19 tests distributed by the US Centers for Disease Control and Prevention (CDC) exhibited false positive reactivity of negative controls due to flaws in assay design and contamination in one of the assay components, according to a CDC internal investigation published this week in the open-access journal PLOS ONE.

15 Dec 2021

Researchers take advantage of virus' sweet tooth in the design of sugar-coated COVID-19 test strip

Even those tracking each new discovery about the coronavirus and its variants may not be aware of the virus' sugar cravings.

15 Dec 2021

Factors associated with having data on SARS-CoV-2 infection and COVID-19 severity

Researchers utilized pre-pandemic information from two UK-based observational population studies to investigate predictors of selection into analytic subsamples in observational studies on SARS-CoV-2 infection and on COVID-19 severity.

15 Dec 2021

T-cell immune response in previously infected and vaccinated individuals effective against SARS-CoV-2 Omicron variant

New findings illustrate that despite the continuous pattern of the ongoing evolution of SARS-CoV-2, it has not resulted in any significant accumulation of CD8+ T-cell escape mutations.

15 Dec 2021

Novel bioinformatics pipeline for fast and scalable analysis of large viral phylogenies

A team of researchers recently developed a bioinformatics approach to analyze viral phylogenetic clusters.

15 Dec 2021

Exploring the possibility of developing a plant-based oral vaccine against COVID-19

New research optimizes methods for the in-planta expression of the recombinant protein corresponding to the Receptor Binding Domain (RBD) subunit of the surface-exposed Spike glycoprotein of SARS-CoV-2.

15 Dec 2021

Receptor binding of SARS-CoV-2 Omicron variant compared to other variants

Researchers compared the binding of the new SARS-CoV-2 VOC Omicron’s RBD and ACE2 receptor with the original Wuhan SARS-CoV-2 strain and other VOCs such as Beta and Delta.

15 Dec 2021

Impact of exogenous antibody therapy by convalescent plasma against SARS-CoV-2

Researches have been investigating the possibility of using convalescent plasma to help patients recover from COVID-19.

15 Dec 2021

Cell surface expression of SARS-CoV-2 nucleocapsid protein and its role in immunity

Researchers demonstrated the unexpected roles of nucleocapsid protein in innate and adaptive immunity to SARS-CoV-2.

15 Dec 2021

Trajectory of SARS-CoV-2 vaccination and immunity examined in new model

Researchers have created a model of looking at the spread of COVID-19 that takes both vaccination rates and rates of loss of immunity into account and can be adjusted as factors change.

15 Dec 2021

SARS-CoV-2 Omicron variant binding to its receptor and therapeutic entities

Researchers generated a set of computed structural models of the Omicron receptor-binding domain attached to its receptor angiotensin-converting enzyme.

15 Dec 2021

Monoclonal antibody activity against SARS-CoV-2 Omicron variant

Scientists from Germany have recently pointed out that the third booster dose of mRNA-based COVID-19 vaccine is highly effective in neutralizing the omicron variant of SARS-CoV-2.

15 Dec 2021

SARS News and Research

Two doses of Moderna COVID-19 vaccine highly effective against all SARS-CoV-2 variants

Evaluation of SARS-CoV-2 neutralizing antibodies in mothers and infants

How SARS-CoV-2 affects the male reproductive system

Evaluation of SARS-CoV-2 Omicron's immune evasion potential

Signatures of rising SARS-CoV-2 Delta infections in New York

SARS-CoV-2 VOCs dependent on IFITM2 for efficient infection establishment

New Canadian study shows how SARS-CoV-2 transmission occurred in schools

Weak T-cell clonal response to SARS-CoV-2 vaccination in IBD patients deficient in antibody-responders

CDC researchers analyze the earliest batch of COVID-19 tests

Researchers take advantage of virus' sweet tooth in the design of sugar-coated COVID-19 test strip

Factors associated with having data on SARS-CoV-2 infection and COVID-19 severity

T-cell immune response in previously infected and vaccinated individuals effective against SARS-CoV-2 Omicron variant

Novel bioinformatics pipeline for fast and scalable analysis of large viral phylogenies

Exploring the possibility of developing a plant-based oral vaccine against COVID-19

Receptor binding of SARS-CoV-2 Omicron variant compared to other variants

Impact of exogenous antibody therapy by convalescent plasma against SARS-CoV-2

Cell surface expression of SARS-CoV-2 nucleocapsid protein and its role in immunity

Trajectory of SARS-CoV-2 vaccination and immunity examined in new model

SARS-CoV-2 Omicron variant binding to its receptor and therapeutic entities

Monoclonal antibody activity against SARS-CoV-2 Omicron variant

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