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New City of Hope CAR T cell trial focuses on HER2-positive breast cancer patients with brain metastases

Women with HER2-positive breast cancer that has spread to the brain need more treatment options, and City of Hope and Mustang Bio Inc. are meeting that challenge.

30 Oct 2018

Study highlights accuracy of DecisionDx-Melanoma prognostic test in patients with Stage II-IIIA melanoma

Castle Biosciences, Inc., the skin cancer diagnostics company providing molecular diagnostics to improve cancer management decisions, today announced the presentation of data highlighting how the accuracy of the DecisionDx-Melanoma gene expression profile (GEP) test in patients with Stage II and IIIA melanoma can improve adjuvant clinical trial design at the 2018 Society for Melanoma Research International Congress held in Manchester, England from October 24-27.

30 Oct 2018

Hyperspectral imaging helps improve patient outcomes after brain tumor surgery

Identifying healthy from diseased tissue poses a unique problem for cancer surgeons. Even the smallest bits of a tumor left behind during surgery can regrow and spread to other organs, a deadly phenomenon called metastasizing.

30 Oct 2018

Study reveals how Seneca Valley Virus interacts with tumor receptors

Seneca Valley Virus sounds like the last bug you’d want to catch, but it could be the next breakthrough cancer therapy.

30 Oct 2018

Ten Allen Distinguished Investigators for 2018 announced by Paul G. Allen Frontiers Group

Nanoparticles that could reprogram a cancer patient's immune system inside their own body. Understanding a mysterious type of brain cell in the hopes of shedding new light on Alzheimer's disease. Reimagining nuclei, the DNA-storage compartments of our cells, as miniature lava lamps.

30 Oct 2018

Scientists find ways to block nitration of amino acids to improve cancer immunotherapy

Immunotherapy -- harnessing T-cells to attack cancer cells in the body -- has given hope to patients who endure round after round of treatment, including chemotherapy, to little effect. For all of its promise, however, immunotherapy still benefits only a minority of patients -- a reality driving research in the field for ways to improve the relatively new approach.

30 Oct 2018

Promising potential of stimuli-responsive nanomaterial for cancer therapy

Nanosystems that deliver anticancer drugs or imaging materials to tumors are showing significant progress, particularly those that respond to tumor-related stimuli, according to a review published in the journal Science and Technology of Advanced Materials.

30 Oct 2018

NEC and Transgene sign MOU for strategic collaboration aimed at treating solid cancers

NEC Corporation and Transgene today announced the signing of a Memorandum of Understanding for a strategic collaboration aimed at the treatment of solid cancers.

30 Oct 2018

Patients receiving individual doses and conventional breast radiation experience similar side effects

In a 10-year study of women who received radiation therapy to treat early-stage breast cancer, those receiving fewer, larger individual doses experienced similarly low rates of late-onset side effects as those undergoing conventional radiation therapy. Findings from the multi-institutional U.K. FAST clinical trial were presented last week at the 60th Annual Meeting of the American Society for Radiation Oncology.

30 Oct 2018

Radiation therapy can lower risk of breast cancer recurrence in patients with ‘good risk’ DCIS

A subset of patients with low-risk breast cancer is highly unlikely to see cancer return following breast conservation surgery but can lower that risk even further with radiation therapy, finds a new long-term clinical trial report.

30 Oct 2018

Quantum dot-based FISH method enhances cell imaging

A team of researchers from the University of Illinois at Urbana-Champaign and Mayo Clinic have engineered a new type of molecular probe that can measure and count RNA in cells and tissue without organic dyes.

30 Oct 2018

Aggressive local therapy for stage IV lung cancer patients improves progression-free survival

Adding radiation therapy or surgery to systemic therapy for stage IV lung cancer patients whose cancer has spread to a limited number of sites can extend overall survival time significantly, according to new results from a multicenter, randomized, controlled phase II study. The findings were presented last week at the 60th Annual Meeting of the American Society for Radiation Oncology

30 Oct 2018

Researchers uncover new insights on cancer growth

Walter and Eliza Hall Institute researchers have uncovered new insights into how the normal controls on cell growth are lost in cancer cells, leading to rapid tumor expansion.

29 Oct 2018

Insights into tumor initiation pave way for new skin cancer treatments

Researchers from VIB and KU Leuven uncovered a key vulnerability of melanoma. While studying the role of the melanoma-specific long non-coding RNA SAMMSON in tumor initiation, the researchers found that it boosts protein synthesis in different cellular compartments. Normal cells are alerted by modification in protein synthesis and react to this threat, but only if this process is altered in one compartment at the time.

29 Oct 2018

DIACARTA introduces new QClamp assays for detection of cancer gene mutations

DIACARTA Inc., a precision molecular diagnostics company headquartered in Richmond, California, today announced that it is launching a new suite of CE-IVD marked highly sensitive hydrolysis probe based QClamp assays for detection of common cancer mutations in genes, such as KRAS, NRAS, BRAF, EGFR, PIK3CA and JAK2, using tissue biopsyand liquid biopsy samples.

29 Oct 2018

Bigger brains linked to greater risk of developing tumors

It may simply be that having a big brain is itself the cause. That's what doctor and PhD candidate Even Hovig Fyllingen at the Norwegian University of Science and Technology (NTNU) has determined with his research colleagues.

29 Oct 2018

Study finds kill code mechanism embedded in every cell to extinguish cancer

A kill code is embedded in every cell in the body whose function may be to cause the self-destruction of cells that become cancerous, reports a new Northwestern Medicine study. As soon as the cell's inner bodyguards sense it is mutating into cancer, they punch in the kill code to extinguish the mutating cell.

29 Oct 2018

Stroke 'mimics' and 'chameleons' can complicate accurate diagnoses

Stroke specialists often see conditions known as stroke "mimics" and "chameleons" that can complicate accurate diagnoses, Loyola Medicine neurologists report in the November 2018 issue of Neuroimaging Clinics of North America.

26 Oct 2018

Turning tumor-promoting fibroblasts against pancreatic cancer

Pancreatic cancer has a grim prognosis. It is usually detected after the disease has spread, and chemotherapy tends to do little to slow the cancer's growth. Even with treatment, most patients live only about six months after they are diagnosed with the disease.

26 Oct 2018

Molecular breakthrough may improve prognosis for pancreatic cancer

Scientists have discovered a method by which fibroblasts in the stroma of pancreatic tumors can be reprogrammed to suppress tumor cell growth.

26 Oct 2018

Tumor News and Research

New City of Hope CAR T cell trial focuses on HER2-positive breast cancer patients with brain metastases

Study highlights accuracy of DecisionDx-Melanoma prognostic test in patients with Stage II-IIIA melanoma

Hyperspectral imaging helps improve patient outcomes after brain tumor surgery

Study reveals how Seneca Valley Virus interacts with tumor receptors

Ten Allen Distinguished Investigators for 2018 announced by Paul G. Allen Frontiers Group

Scientists find ways to block nitration of amino acids to improve cancer immunotherapy

Promising potential of stimuli-responsive nanomaterial for cancer therapy

NEC and Transgene sign MOU for strategic collaboration aimed at treating solid cancers

Patients receiving individual doses and conventional breast radiation experience similar side effects

Radiation therapy can lower risk of breast cancer recurrence in patients with ‘good risk’ DCIS

Quantum dot-based FISH method enhances cell imaging

Aggressive local therapy for stage IV lung cancer patients improves progression-free survival

Researchers uncover new insights on cancer growth

Insights into tumor initiation pave way for new skin cancer treatments

DIACARTA introduces new QClamp assays for detection of cancer gene mutations

Bigger brains linked to greater risk of developing tumors

Study finds kill code mechanism embedded in every cell to extinguish cancer

Stroke 'mimics' and 'chameleons' can complicate accurate diagnoses

Turning tumor-promoting fibroblasts against pancreatic cancer

Molecular breakthrough may improve prognosis for pancreatic cancer

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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