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Study investigates the degree of Covid-19 vaccination protection in dialysis patients

Researchers led by the Marien Hospital Herne, a Ruhr-Universität Bochum clinic, have investigated the extent to which mRNA vaccines protect dialysis patients from infection with variants of concerns of Sars-Cov-2.

12 Nov 2021

Study may pave the way for a more personalized approach to COVID-19 diagnosis and treatment

Using some of the most advanced molecular sequencing tools available to evaluate COVID-19 rapid autopsy tissues, researchers have identified four major regulatory pathways, specific molecular effectors behind COVID-19 symptoms, and differences that drive diverging clinical courses among individual patients.

11 Nov 2021

Analysis of immunodeficient patients granted REGEN-COV under compassionate use COVID-19 program

A team of scientists describe the safety and response to REGEN-COV® for COVID-19 patients with immunodeficiency-associated antibody disorders.

11 Nov 2021

Vaccinated patients hospitalized with COVID-19 in Norway spend fewer days in the hospital

A recent study looks at how mRNA vaccination affects hospitalization and ICU admission in COVID-19 breakthrough infections.

11 Nov 2021

Study shows 90.7% efficacy for the BNT162b2 COVID vaccine in 5-11 year-olds

A new study evaluates the safety, immunogenicity, and efficacy of the BNT162b2 in children who were 5 to 11 years of age.

11 Nov 2021

RT-LAMP coupled solid-state nanopores for SARS-CoV-2 detection

Researchers discuss a highly sensitive, specific, and rapid SARS-CoV-2 detection platform by coupling the RT-LAMP with glass nanopore sensors.

11 Nov 2021

Long-term effectiveness of Pfizer/BioNTech two-dose regimen mRNA vaccine

A group of scientists from Israel sought to evaluate the long-term effectiveness of the BioNTech/Pfizer mRNA BNT162b2 vaccine.

11 Nov 2021

Long-lasting anti-spike and anti-membrane antibodies can differentiate between COVID-19 infection and vaccination

Researchers have been investigating which other proteins remain prevalent long enough for tests against them to be worthwhile.

11 Nov 2021

New Delta sublineage shows no additional resistance to neutralization

Researchers are attempting to determine the ability of this new sublineage to avoid neutralization by antibodies elicited from vaccination.

11 Nov 2021

Immunity following COVID-19 vaccination and natural infection in India

The researchers evaluated immune response markers in a cross-section of people from the Indian state of West Bengal, including those vaccinated with either Covishield or Covaxin, the unvaccinated cohort, and the naturally infected.

11 Nov 2021

Association between SARS-CoV-2 infections and areal level deprivation and ethnicity in England

A new study from the UK shows that the presence of inequality favors a heavier impact and that this showed dynamic changes as policies changed and newer virus variants emerged.

11 Nov 2021

COVID-19 trends identified from multiple linked EHR

In this study, the sociodemographic factors, occurrence of health conditions, the effect of the first and second waves in England, and vaccination effects, were considered separately.

11 Nov 2021

Corrected method for more accurate estimation of SARS-CoV-2 reproduction number

Scientists have recently proposed and applied a correction to EpiEstim, a statistical method to estimate the time-dependent transmission of infectious disease during an epidemic.

11 Nov 2021

Phage-like particle system provides a platform for quick and easy vaccine generation

In this study, researchers report on the development of a monovalent lambda PLP-based vaccine against SARS-CoV-2 or MERS-Cov through decoration with the spike RBD proteins from either virus.

11 Nov 2021

Effectiveness of sotrovimab demonstrated in patients with mild to moderate COVID-19

In an attempt to study the safety and effectiveness of sotrovimab in more vulnerable patients suffering from mild to moderate symptoms of COVID-19, a multinational team of researchers conducted the COVID-19 Monoclonal antibody Efficacy Trial-Intent to Care Early (COMET-ICE) trial.

11 Nov 2021

REGEN-COV shown to rapidly reduce SARS-CoV-2 viral load in hospitalized COVID-19 patients

Studies have shown that mortality rates in hospitalized patients with COVID-19 are high, ranging between 10% and 30%. REGEN-COV®, a combination of monoclonal antibodies casirivimab and imdevimab, is approved in the United States and other regions for emergency treatment of COVID-19 outpatients with mild to moderate SARS-CoV-2 infection and post-exposure prophylaxis.

10 Nov 2021

Surveillance approaches to monitor the presence of SARS-CoV-2 in a fully vaccinated population

Researchers at the University of Calgary Health Technology Assessment Unit investigated scientific evidence on various surveillance and testing methods to monitor the presence of the virus in a vaccinated population.

10 Nov 2021

Evidence that mild and even asymptomatic SARS-CoV-2 infection can lead to sustained immune activation

A paper published in the open-access journal Viruses, reports on a study investigating long-term changes to soluble inflammatory factors and cellular immune phenotype and function in 22 survivors of mild SARS-CoV-2 infection. The observations were then compared to 11 individuals who had recovered from other mild respiratory infections.

10 Nov 2021

New discovery could lead to the creation of a pan-coronaviruses vaccine

Next generation vaccines for Covid-19 should aim to induce an immune response against 'replication proteins', essential for the very earliest stages of the viral cycle, concludes new research carried out by UCL scientists.

10 Nov 2021

First detection of SARS-CoV-2 remdesivir resistance in an immunocompromised patient

A research group from the US (led by experts from Yale University School of Medicine) recently presented a case of an immunocompromised female patient with acquired deficiency of B lymphocytes who subsequently developed a protracted course of the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

10 Nov 2021

SARS News and Research

Study investigates the degree of Covid-19 vaccination protection in dialysis patients

Study may pave the way for a more personalized approach to COVID-19 diagnosis and treatment

Analysis of immunodeficient patients granted REGEN-COV under compassionate use COVID-19 program

Vaccinated patients hospitalized with COVID-19 in Norway spend fewer days in the hospital

Study shows 90.7% efficacy for the BNT162b2 COVID vaccine in 5-11 year-olds

RT-LAMP coupled solid-state nanopores for SARS-CoV-2 detection

Long-term effectiveness of Pfizer/BioNTech two-dose regimen mRNA vaccine

Long-lasting anti-spike and anti-membrane antibodies can differentiate between COVID-19 infection and vaccination

New Delta sublineage shows no additional resistance to neutralization

Immunity following COVID-19 vaccination and natural infection in India

Association between SARS-CoV-2 infections and areal level deprivation and ethnicity in England

COVID-19 trends identified from multiple linked EHR

Corrected method for more accurate estimation of SARS-CoV-2 reproduction number

Phage-like particle system provides a platform for quick and easy vaccine generation

Effectiveness of sotrovimab demonstrated in patients with mild to moderate COVID-19

REGEN-COV shown to rapidly reduce SARS-CoV-2 viral load in hospitalized COVID-19 patients

Surveillance approaches to monitor the presence of SARS-CoV-2 in a fully vaccinated population

Evidence that mild and even asymptomatic SARS-CoV-2 infection can lead to sustained immune activation

New discovery could lead to the creation of a pan-coronaviruses vaccine

First detection of SARS-CoV-2 remdesivir resistance in an immunocompromised patient

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