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Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

Researchers at Yale School of Medicine have discovered that an RNA molecule that stimulates the body's early antiviral defense system can protect mice from a range of emerging SARS-CoV-2 variants.

10 Nov 2021

Emergence of SARS-CoV-2 immune escape variants in an immunocompromised patient

A German case study recently published in the journal Nature Communications has characterized a long-term severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection dynamics in an immunosuppressed kidney transplant recipient and provided evidence for the evolution of SARS-CoV-2 into potentially harmful immune escape mutants during persistent infections.

10 Nov 2021

Risk of severe COVID-19 is rare among fully vaccinated individuals in England

A team of UK-based scientists has recently estimated the prevalence of vaccine breakthrough infections and severe disease in a large number of individuals fully vaccinated against coronavirus disease 2019 (COVID-19) in England.

10 Nov 2021

Coronaviruses synthesize RNA in membrane-bound compartments

A team of researchers show that IBV viral RNA synthesis occurs within the membrane-bound compartment

10 Nov 2021

The immune response elicited by an inactivated SAR-CoV-2 vaccine

A team of researchers assessed antibody responses to the inactivated SARS-CoV-2 vaccine among vaccine recipients in Shenzhen, China.

10 Nov 2021

The SARS-CoV-2 Beta variant evades Fc effector function by ancestral strain, study says

A new study finds improved Fc cross-reactivity against certain SARS-CoV-2 variant of concern.

10 Nov 2021

Stenoparib effectively inhibits SARS-CoV-2 variants in vitro

A new study assesses the antiviral activity of stenoparib against four SARS-CoV-2 strains.

10 Nov 2021

The autoantibody profile in COVID-19 patients with MIS-C

A new study assessed the presence of autoantibodies against autoantigens associated with known autoimmune diseases in patients with COVID-19.

10 Nov 2021

Current understanding of the link between COVID-19 and cardiovascular disease

A review published in Chemo-Biological Interactions has focused on the prevalence of COVID-19 in CVD patients associated with ACE2 mechanisms.

10 Nov 2021

Chronological changes in SARS-CoV-2 immune responses after BNT162b2 vaccine

A new study focused on the chronological changes in humoral and cell-mediated immune responses, during and after the BNT162b2 vaccine administration, among hospital workers of a national medical institution in Japan.

10 Nov 2021

Cell-based viral replication system for screening of SARS-CoV-2 drugs

The current study reports a SARS-CoV-2 replicon system within stable cell lines that can be cultured with ease in a standard biosafety level 2 laboratory.

10 Nov 2021

How effective are mask-wearing and social distancing in UK universities?

A new paper describes the effects of various non-pharmaceutical interventions in dealing with the spread of this virus among students, faculty, and staff on university campuses following the reopening of these institutions.

10 Nov 2021

Mechanism of SARS-CoV-2 antibody transfer into breastmilk

A recent study aimed to understand better the mechanism of antibody transfer to breastmilk in the setting of SARS-CoV-2 infection.

10 Nov 2021

Mechanisms and strategies for antibody binding and escape in SARS-CoV-2

A new study investigated the mechanisms for binding and strategies to escape several hNAbs used by SARS-CoV-2 strains through molecular simulations.

10 Nov 2021

Finnish study highlights the need for mRNA COVID vaccine booster shots

A register-based cohort study of the effectiveness of COVID-19 vaccines was performed to help decision-making on providing booster doses to social and healthcare workers (HCWs) like nurses, physicians, dentists, and other professionals in Finland. In addition, it estimated the vaccine effectiveness after the second dose. This study is published on the medRxiv* preprint server.

9 Nov 2021

COVID-19 vaccination strategies that minimize R0 may offer greater protection to vulnerable age groups

In this study, researchers aimed at finding the minimum vaccination rate for each age group that guaranteed the basic reproduction number R0 was less than 1, thus stabilizing the dynamics at the disease-free equilibrium.

9 Nov 2021

Study: Most pediatric cancer patients have mild COVID-19 and make full recovery

Most children and adolescents with cancer have mild COVID-19 disease and make a full recovery, a new study has found. But pediatric cancer patients with underlying health conditions, severe infections and low white blood cell counts were significantly more likely to have severe disease.

9 Nov 2021

Favourable meta-analysis of inhaled corticosteroids in COVID-19 outpatients

Two open-label randomized controlled trials (RCTs) on the use of inhaled corticosteroids such as budesonide in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients have helped garner attention towards inhaled corticosteroids as a safe and inexpensive treatment method in non-hospitalized SARS-CoV-2 patients.

9 Nov 2021

Birmingham Biotech partners with University of Birmingham to commercialize novel anti-viral nasal spray

Birmingham Biotech Ltd, an innovator in diagnostic tests, protective nasal sprays and mobile medical facilities, and the University of Birmingham have signed a licensing agreement to commercialise a novel anti-viral nasal spray that protects against COVID-19.

9 Nov 2021