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Targeting excessive calcium may provide a new way to improve outcomes in stroke patients

Excessive calcium contributes to harmful inflammation in ischemic stroke, and targeting it may provide doctors with a new way to improve patient outcomes, new research from the University of Virginia School of Medicine suggests.

23 Nov 2020

Chicago seroprevalence study shows COVID-19 cases 16 times higher than currently predicted

A startling new case study of Chicago, led by a team of researchers at Northwestern University in Illinois, USA, suggests a 16-fold higher incidence of SARS-CoV-2 infection than previously thought. This is judging from seroprevalence (antibody presence blood testing) figures, rather than the number of RT-PCR-positives reported there (via swab sample testing of symptomatic patients).

23 Nov 2020

FDA schedules meeting to discuss emergency use authorization of COVID-19 vaccine from Pfizer

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for casirivimab and imdevimab to be administered together for the treatment of mild to moderate COVID-19 in adults and pediatric patients (12 years of age or older weighing at least 40 kilograms [about 88 pounds]) with positive results of direct SARS-CoV-2 viral testing and who are at high risk for progressing to severe COVID-19.

23 Nov 2020

Researchers discover mechanism by which abnormal proteins unleash toxicity in neurodegenerative diseases

Thanks to modern medicine, humans tend to live much longer than before. Unfortunately, this also opens a wider window to develop chronic diseases with late onset, such as neurodegenerative diseases.

23 Nov 2020

Scientists investigate how cell membrane and COVID-19 virus impact each other

The cell membrane is the cell's outermost line of defense against SARS-CoV-2, the novel coronavirus responsible for COVID-19 disease.

20 Nov 2020

Chemists discover effective inhibitors to block SARS-CoV-2

Some viruses can get inside cells via a mechanism that involves sulfur organic molecules. Chemists at UNIGE have discovered effective inhibitors and blocked the uptake of SARS-CoV-2.

20 Nov 2020

Non-invasive point of care imaging can aid rapid diagnosis of corneal infections

Simple, non-invasive imaging at the point of care can aid the diagnosis of corneal infections, reducing the risk of sight loss and helping patients' vision return to pre-infection levels.

20 Nov 2020

Researchers receive coveted award for outstanding research on COVID-19

The 2020 ACM Gordon Bell Special Prize for High Performance Computing-Based COVID-19 Research was presented to a 12-member team for their project "AI-Driven Multiscale Simulations Illuminate Mechanisms of SARS-CoV-2 Spike Dynamics."

20 Nov 2020

Multi-institution team receives prestigious award for breakthrough research on SARS-CoV-2

The Association for Computing Machinery (ACM) awarded its first ACM Gordon Bell Special Prize for High Performance Computing-Based COVID-19 Research to a multi-institution research team that included the U.S. Department of Energy's (DOE) Argonne National Laboratory.

20 Nov 2020

Study highlights the role of genetic testing in evaluation of in-stent thrombosis

In a new publication from Cardiovascular Innovations and Applications, Nathan Burke, Tawanna Charlton, Hussam Hawamdeh, and Ki Park from the University of Florida College of Medicine, Gainesville.

20 Nov 2020

Study shows how rotavirus leads to severe gastrointestinal disease

Rotavirus is a major cause of diarrhea and vomiting, especially in children, that results in approximately 128,000 deaths annually.

20 Nov 2020

Study provides new way to develop unconventional anticancer strategies

There is considerable interest in a new class of anticancer molecules that is currently still under investigation termed the cationic antimicrobial peptides (AMPs).

20 Nov 2020

Researchers map perception of complex blends of odorants

Fragrances - promising mystery, intrigue, and forbidden thrills - are blended by master perfumers, their recipes kept secret.

20 Nov 2020

Authors demonstrate process of misdiagnosis to improve the understanding of congenital heart defect

In a new publication from Cardiovascular Innovations and Applications, Lei Zhang, Tiewei Lv, Xiaoyan Liu, Chuan Feng, Min Zheng, Jie Tian and Huichao Sun from the Children's Hospital of Chongqing Medical University, Chongqing, China and the Chongqing Key Laboratory of Pediatrics, Chongqing, China consider a case of pediatric heart failure caused by the anomalous origin of the left coronary artery from the pulmonary artery.

20 Nov 2020

Revised manufacturing process for surgical gloves can save more time, energy

Cranfield University researchers in partnership with Meditech Gloves, one of the leading manufacturers of high-quality examination and surgical gloves, have shown how energy savings can be made with the development of more sustainable, biodegradable, protein-free, natural rubber gloves.

19 Nov 2020

Antibody combinations may be more effective at preventing, treating COVID-19

Pairs of antibodies may be more effective than single antibodies at preventing and treating COVID-19, according to a new study by researchers at the University of North Carolina at Chapel Hill and The Rockefeller University in New York.

19 Nov 2020

Researchers uncover potential new target to fight inflammatory diseases

An international team of researchers have uncovered a drug-like compound that blocks a crucial inflammatory pathway, potentially paving the way for a new treatment for a host of diseases - including COVID-19.

19 Nov 2020

Detectable SARS-CoV-2 antibodies 120 days post-infection in Chicago case study

In a recent study, a team of researchers at Northwestern University, USA, had found that nearly 20 percent seroprevalence in the United States metropolitan site, Chicago, over the summer, during a period when lockdown restrictions were eased. They found that three-quarters of seropositive individuals retained detectable antibodies for at least 120 days or four months.

19 Nov 2020

Teenagers facing COVID-19 and EVALI show similar symptoms

A UC Davis Health pediatric team presented a powerful case series of three teenagers who had unexplained breathing problems during the COVID-19 pandemic.

19 Nov 2020

Scientists discover potential strategy to prevent inflammation in COVID-19 patients

The COVID-19 pandemic continues to cause significant illness and death while treatment options remain limited. St. Jude Children's Research Hospital scientists have discovered a potential strategy to prevent life-threatening inflammation, lung damage and organ failure in patients with COVID-19. The research appeared online in the journal Cell.

19 Nov 2020

Laboratory News and Research

Targeting excessive calcium may provide a new way to improve outcomes in stroke patients

Chicago seroprevalence study shows COVID-19 cases 16 times higher than currently predicted

FDA schedules meeting to discuss emergency use authorization of COVID-19 vaccine from Pfizer

Researchers discover mechanism by which abnormal proteins unleash toxicity in neurodegenerative diseases

Scientists investigate how cell membrane and COVID-19 virus impact each other

Chemists discover effective inhibitors to block SARS-CoV-2

Non-invasive point of care imaging can aid rapid diagnosis of corneal infections

Researchers receive coveted award for outstanding research on COVID-19

Multi-institution team receives prestigious award for breakthrough research on SARS-CoV-2

Study highlights the role of genetic testing in evaluation of in-stent thrombosis

Study shows how rotavirus leads to severe gastrointestinal disease

Study provides new way to develop unconventional anticancer strategies

Researchers map perception of complex blends of odorants

Authors demonstrate process of misdiagnosis to improve the understanding of congenital heart defect

Revised manufacturing process for surgical gloves can save more time, energy

Antibody combinations may be more effective at preventing, treating COVID-19

Researchers uncover potential new target to fight inflammatory diseases

Detectable SARS-CoV-2 antibodies 120 days post-infection in Chicago case study

Teenagers facing COVID-19 and EVALI show similar symptoms

Scientists discover potential strategy to prevent inflammation in COVID-19 patients

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