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A promising new vaccine for SARS-CoV-2 and influenza

Researchers create a vaccine candidate that could protect against both SARS-CoV-2 and IAVs.

27 Feb 2022

Study reveals how the immune system can be triggered to fight cancer cells

New research from the University of East Anglia and Quadram Institute reveals how our immune system can be triggered to attack cancer cells.

25 Feb 2022

Research could pave the way for adoption of precision medicine approaches for COVID-19

The COVID-19 pandemic has revealed a frightening reality; the course of infection with this disease is highly variable. Some young patients have died from the virus, whereas several elderly people have survived without experiencing respiratory symptoms at all. Researchers are left wondering: why?

25 Feb 2022

Declining immune responses against SARS-CoV-2 variants in dialysis patients post-vaccination

Researchers examined systemic B and T cell responses 16 weeks after BNT162b2 vaccination, and the potency of vaccine-induce neutralizing antibodies, in hemodialysis patients and healthcare workers with no comorbidities.

25 Feb 2022

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Researchers characterized humoral and SARS-CoV-2 S-specific T cell responses in IBD patients who received two-dose mRNA-based COVID-19 vaccination series.

25 Feb 2022

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection.

24 Feb 2022

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Researchers sought to evaluate the zoonotic potential of BOMV to assess the level of risk to public health.

24 Feb 2022

Study reveals sex-dimorphic immune imprints and in vivo functional impacts of mild COVID-19

Researchers used a systems immunology approach to analyze the immune states of healthy and non-obese subjects who recovered from mild COVID-19 and compared them with age- and sex-matched COVID-19-naive controls.

24 Feb 2022

Immune responses in patients with varying degrees of SARS-CoV-2 infection

In a recent research article published in the journal PLoS ONE, researchers looked at immunological responses in relation to established risk factors for serious illness. This prospective cohort study reports on long-lasting SARS-CoV-2 specific antibody and T-cellular immune responses six months after infection in rt-PCR confirmed cases of different illness severity (community and hospitalized patients).

24 Feb 2022

Study explores the impact of COVID-19 on pancreatic cells

New study findings showed that SARS-CoV-2 caused a productive yet restricted infection of pancreatic islet cells and an insignificant inflammatory response.

23 Feb 2022

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

Researchers investigated the effectiveness of the BCG vaccines against SARS-CoV-2 infections using three animal models.

23 Feb 2022

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

In a recent study posted to the Research Square* preprint server, which is under consideration at Scientific Reports, a team of researchers developed a novel human Alveolar Epithelial Lentivirus immortalized (hAELVi) cell infection model to estimate the replication potential of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses in the lower respiratory tract of humans.

23 Feb 2022

Interferon News and Research

A promising new vaccine for SARS-CoV-2 and influenza

Study reveals how the immune system can be triggered to fight cancer cells

Research could pave the way for adoption of precision medicine approaches for COVID-19

Declining immune responses against SARS-CoV-2 variants in dialysis patients post-vaccination

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Study reveals sex-dimorphic immune imprints and in vivo functional impacts of mild COVID-19

Immune responses in patients with varying degrees of SARS-CoV-2 infection

Study explores the impact of COVID-19 on pancreatic cells

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

hAELVi cell infection model mimics SARS-CoV-2 Omicron infection in lower respiratory tract of humans

Mathematical model of host immune response to SARS-CoV-2 demonstrates that age-related risk factors increased viral load

Study suggests non-classical inhibition of TBK1/IKKε is protective against severe COVID-19 immunopathology in vivo

Gradual decline in pathogenicity and enhanced cytokine induction in SARS-CoV-2 variants

Study reports a highly attenuated SARS-CoV-2 that could serve as a live-attenuated vaccine platform

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

Study finds antigenic profile of Omicron RBD is distinct from the prior SARS-CoV-2 variants of concern

Study explores humoral and cellular immunity conferred by second and third COVID-19 BNT162b2 vaccination in elderly

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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