Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

NIH awards grants for using bioengineered models to improve clinical trial design

Clinical Trials on a Chip researchers plan to build and test common and rare disease models to help improve the clinical trial process.

30 Sep 2020

NIH-funded nationwide study seeks to discover the cause of rare forms of diabetes

A nationwide study funded by the National Institutes of Health will seek to discover the cause of several unusual forms of diabetes.

30 Sep 2020

Newly developed fusion protein could improve COVID-19 research

Researchers at the Paul Scherrer Institute in Switzerland have developed a high-quality recombinant virus protein that could be applied in the development of vaccines against the 2019 novel coronavirus (2019-nCoV) and in the detection of novel viruses or antibodies.

30 Sep 2020

Researchers develop research model to understand the impact of coronavirus on lungs

Scientists at Boston University's National Emerging Infectious Diseases Laboratories (NEIDL) and the Center for Regenerative Medicine (CReM) joined forces to develop the most relevant research model possible for understanding how the coronavirus virus impacts the lungs, by engineering living, "breathing" human lung cells from stem cells for the task.

30 Sep 2020

All-in-one surgical approach is a safe and viable option for patients with polycystic kidney disease

Patients with large polycystic kidneys in need of a kidney transplant can have their diseased kidneys safely removed laparoscopically at the same time as their transplant surgery. That is the finding of a Mayo Clinic study recently published in the American Journal of Transplantation.

29 Sep 2020

‘No Mercy’ explores the fallout after a small town loses its hospital

Midwesterners aren’t known for complaining. But after Mercy Hospital Fort Scott closed, hardship trickled down to people whose lives were already hard.

29 Sep 2020

Induction of acute senescence may be a necessary process in hemorrhagic shock

It's called senescence, when stressed cells can no longer divide to make new cells, and it's considered a factor in aging and in some diseases.

29 Sep 2020

Study unravels how lysosomal damage response pathways prevent kidney injury

Human cells need to work like well-oiled machines to keep our bodies running as they should. Waste products such as misfolded proteins, damaged cellular components, and carbohydrates get in the way and must be quickly disposed of.

28 Sep 2020

Hamsters and ferrets clear low dose SARS-CoV-2 infection in 14 days

A recent study by French researchers has demonstrated that experimental exposure to severe acute respiratory coronavirus 2 (SARS-CoV-2) is capable of inducing mild infection in hamsters and ferrets within 7 – 10 days of exposure. However, the infection completely resolves within 14 days. The study is currently available on the bioRxiv preprint server.

28 Sep 2020

Resveratrol and pterostilbene inhibit SARS-CoV-2 infection in vitro

A team of scientists at the University of Groningen, in the Netherlands, demonstrates that a natural plant product, resveratrol, and its structural analog, pterostilbene, have long-lasting antiviral effects against severe acute respiratory coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the bioRxiv preprint server.

28 Sep 2020

Study finds new treatment approach for patients with salt sensitive hypertension

High blood pressure (hypertension) affects one in two U.S. adults and can cause hardening and thickening of the arteries (atherosclerosis), which can lead to heart attacks, strokes or other complications including chronic kidney disease.

28 Sep 2020

Research reveals how genetic differences in body fat affect men and women's health risks

New research is revealing how genetic differences in the fat in men's and women's bodies affect the diseases each sex is likely to get.

28 Sep 2020

Newer Type 2 diabetes medications could reduce kidney, heart disease risks

Two newer groups of medications prescribed primarily for Type 2 diabetes treatment (SGLT2 inhibitors and GLP-1 receptor agonists) could significantly reduce risks associated with chronic kidney disease (CKD) and heart disease.

28 Sep 2020

Special formulation of inhaled niclosamide may be effective against SARS-CoV-2

Now in new research published on the preprint server bioRxix*, a novel formulation of the drug Niclosamide (NIC) is observed to be effective against SARS-CoV-2 and MERS-CoV in mouse models; it also protects against methicillin-resistance Staphylococcus aureus pneumonia and inflammatory lung damage.

28 Sep 2020

Risk factors for mortality among hospitalized patients with COVID-19

A new study by scientists at biotechnology company Genentech, Inc., and published on the preprint server medRxiv in September 2020 attempts to identify the factors which may shape the risk for death in COVID-19 disease.

27 Sep 2020

Shorter time from COVID-19 symptom onset to hospitalization linked to disease severity, death

New research presented at this week's ESCMID Conference on Coronavirus Disease (ECCVID, held online) shows that a shorter time from symptom onset to hospitalization is associated with more serious disease and death in patients with COVID-19.

26 Sep 2020

ECMO appears to be saving the lives of many critically ill COVID-19 patients

It saved lives in past epidemics of lung-damaging viruses. Now, the life-support option known as ECMO appears to be doing the same for many of the critically ill COVID-19 patients who receive it, according to a new international study.

26 Sep 2020

WHO plans to increase access to affordable, quality-assured testing and treatment for diabetes

Over a four-day workshop that ended on 25 September 2020, WHO and key international health partners mapped out a plan to boost access to affordable and quality-assured testing and treatment for diabetes.

26 Sep 2020

NIH awards $1.9 million STTR grant to fast track new class of non-opioid pain relievers

The National Institute of Neurological Disorders and Stroke of the National Institutes of Health (NIH) has awarded a $1.9 million Fast-Track Small Business Technology Transfer grant to South Rampart Pharma.

25 Sep 2020

University of Minnesota receives funding to initiate research on diabetes drug as a COVID-19 treatment

University of Minnesota Medical School researchers received funding from the Parsemus Foundation to initiate research on the widely-used diabetes medication, metformin, available globally as an inexpensive generic drug for prevention and treatment for COVID-19.

25 Sep 2020

Nephrology News and Research

Further Reading

NIH awards grants for using bioengineered models to improve clinical trial design

NIH-funded nationwide study seeks to discover the cause of rare forms of diabetes

Newly developed fusion protein could improve COVID-19 research

Researchers develop research model to understand the impact of coronavirus on lungs

All-in-one surgical approach is a safe and viable option for patients with polycystic kidney disease

‘No Mercy’ explores the fallout after a small town loses its hospital

Induction of acute senescence may be a necessary process in hemorrhagic shock

Study unravels how lysosomal damage response pathways prevent kidney injury

Hamsters and ferrets clear low dose SARS-CoV-2 infection in 14 days

Resveratrol and pterostilbene inhibit SARS-CoV-2 infection in vitro

Study finds new treatment approach for patients with salt sensitive hypertension

Research reveals how genetic differences in body fat affect men and women's health risks

Newer Type 2 diabetes medications could reduce kidney, heart disease risks

Special formulation of inhaled niclosamide may be effective against SARS-CoV-2

Risk factors for mortality among hospitalized patients with COVID-19

Shorter time from COVID-19 symptom onset to hospitalization linked to disease severity, death

ECMO appears to be saving the lives of many critically ill COVID-19 patients

WHO plans to increase access to affordable, quality-assured testing and treatment for diabetes

NIH awards $1.9 million STTR grant to fast track new class of non-opioid pain relievers

University of Minnesota receives funding to initiate research on diabetes drug as a COVID-19 treatment

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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