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Researchers develop novel microscopy to observe cellular focal adhesion dynamics

Focal adhesions are large specialized proteins that are located in the area where a cell membrane meets the extracellular matrix, a collection of molecules surrounding the cells that provide support and regulate micromechanical signals to the cells.

4 Jun 2018

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

Reporting results from a first-in-human phase I clinical trial, researchers at University of California San Diego School of Medicine have found that treatment with cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the "stemness" of chronic leukemia cancer cells - their ability to self-renew and resist terminal differentiation and senescence.

1 Jun 2018

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

The University of Texas MD Anderson Cancer Center and Amgen today announced two multi-year collaboration agreements aimed at accelerating development of a variety of Amgen's early-stage oncology therapies for patients with leukemia, myelodysplastic syndromes, multiple myeloma, small-cell lung cancer, and other non-lung cancers with small-cell histologies.

1 Jun 2018

Cancer cells can use lipid molecules as fuel for growth, shows study

Cancer cells can when the blood supply is low use lipid molecules as fuel instead of blood glucose. This has been shown in animal tumor models by researchers at Karolinska Institutet in Sweden in a study published in Cell Metabolism.

1 Jun 2018

New system for anti-cancer drug delivery offers hope to treat pediatric tumors

In most of the Western World, cancer is the primary cause of death in children over the age of one. Existing treatments for adult cancer patients are not particularly effective for children.

31 May 2018

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Treating inflammatory diseases of the bowel is extremely challenging: Genes, gut microbes and disrupted immune function all contribute.

31 May 2018

Scientists introduce combination approach to fight cancer

For efficient cancer therapy with few side effects, the active drug should selectively attain high concentration in the tumor. In the journal Angewandte Chemie, scientists have introduced a new approach, in which two synergistic drug components are combined into a dimer.

31 May 2018

Scientists identify 'hidden' driver that helps prime the anti-tumor immune response

Like exposing a crime boss whose authority has gone undetected, St. Jude Children's Research Hospital scientists have identified a hidden driver that influences production of the T cells that fight cancer and infections. The study appears today as an advance online publication in the journal Nature.

31 May 2018

New guideline for HER2 testing in breast cancer benefits patients and clinicians

Published today, a Focused Update to the American Society of Clinical Oncology/College of American Pathologists guideline for human epidermal growth factor receptor 2 (HER2) testing in breast cancer brings new levels of clarity that will benefit patients and clinical teams alike.

31 May 2018

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

New Cleveland Clinic research shows for the first time that ibrutinib, an FDA-approved drug for lymphoma and leukemia, may also help treat the most common – and deadliest – type of brain tumor.

30 May 2018

Researchers craft mathematical model to understand how cancer evolves

The concept of survival of the fittest most often applies to the competition that occurs within and between animal species, but evolutionary pressures can be found elsewhere--even in a cancerous tumor.

30 May 2018

Radiotherapy drug used for treating rare neuroendocrine cancers can be safe, effective for patients

A radiotherapy drug that treats the rare neuroendocrine cancers pheochromocytoma and paraganglioma can be both effective and safe for patients, according to the findings of a multi-center trial led by researchers in the Abramson Cancer Center of the University of Pennsylvania.

30 May 2018

Scientists develop a new approach for efficient cancer therapy

For efficient cancer therapy with few side effects, the active drug should selectively attain high concentration in the tumor.

30 May 2018

Small defect in tissues can lead normal cells to take on characteristics of diseased cells

Homeowners know that one little termite can lead to big problems: while termites are efficient at gnawing away at wood, they can do even more damage if the wood is already broken or has another defect.

29 May 2018

UH biomedical engineer wins NSF Career Award to improve nanoparticle drug delivery

The National Science Foundation has awarded University of Houston biomedical engineer Sheereen Majd the Career Award and $500,000 to improve nanoparticle drug delivery.

29 May 2018

Researchers identify novel target for bladder cancer

Researchers have identified an olfactory receptor in the human bladder that could prove useful in the diagnosis and treatment of bladder cancer.

29 May 2018

New study shows how to personalize lung cancer screening decision for every patient

For smokers and former smokers, the threat of lung cancer always lurks in the shadows.To flush it out of the darkness, some decide to get their lungs scanned by a CT machine, which can find a tumor early enough to stop it – or set off a false alarm that turns out to be nothing.

29 May 2018

Anti-inflammatory strategy could lead to improved survival of children with neuroblastoma

Researchers at Karolinska Institutet and Karolinska University Hospital have discovered that an anti-inflammatory drug candidate inhibiting the prostaglandin E2 producing enzyme mPGES-1 in the tumor stroma reduces tumor growth in experimental neuroblastoma models.

28 May 2018

Genome dark matter provides clues to fighting prostate cancer

Through studying the dark matter of the human genome, a team from the University of Michigan has shed light on how the hormone androgen drives prostate cancer and suggested a potential target for future therapy.

28 May 2018

Tumor News and Research

Researchers develop novel microscopy to observe cellular focal adhesion dynamics

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

Cancer cells can use lipid molecules as fuel for growth, shows study

New system for anti-cancer drug delivery offers hope to treat pediatric tumors

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Scientists introduce combination approach to fight cancer

Scientists identify 'hidden' driver that helps prime the anti-tumor immune response

New guideline for HER2 testing in breast cancer benefits patients and clinicians

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

Researchers craft mathematical model to understand how cancer evolves

Radiotherapy drug used for treating rare neuroendocrine cancers can be safe, effective for patients

Scientists develop a new approach for efficient cancer therapy

Small defect in tissues can lead normal cells to take on characteristics of diseased cells

UH biomedical engineer wins NSF Career Award to improve nanoparticle drug delivery

Researchers identify novel target for bladder cancer

New study shows how to personalize lung cancer screening decision for every patient

Anti-inflammatory strategy could lead to improved survival of children with neuroblastoma

Genome dark matter provides clues to fighting prostate cancer

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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