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No excess mortality during the Delta variant era in US state with high vaccination rates

Researchers have investigated the number of excess deaths during the initial spread of the Delta variant.

24 Sep 2021

A daily pill to treat covid could be just months away, scientists say

Within a day of testing positive for covid-19 in June, Miranda Kelly was sick enough to be scared. At 44, with diabetes and high blood pressure, Kelly, a certified nursing assistant, was having trouble breathing, symptoms serious enough to send her to the emergency room.

24 Sep 2021

Research shows ozone as a potential disinfectant agent in public transport

The Hydrens team of researchers developed a numerical model that estimates the ozone concentration needed to meet the disinfection criteria. To do this, it takes into account the geometry and volume of the space to be treated, the type of materials inside it and their capacity to absorb ozone, and the characteristics of the impulsion-distribution system used.

24 Sep 2021

Human milk antibodies elicited by vaccination show reduced activity against SARS-CoV-2 VoCs

In a study recently published on the medRxiv* preprint server, scientists from Singapore have assessed the levels of IgA-specific anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the breast milk of women recently immunized with the second dose of an mRNA-based coronavirus disease 2019 (COVID-19) vaccine.

24 Sep 2021

Effect of prior SARS-CoV-2 infection on post-vaccination SARS-CoV-2 spike IgG antibodies

Natural infection or vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) confer considerable protection against reinfection and reduce the risk of severe Coronavirus disease 2019 (COVID-19) outcomes.

24 Sep 2021

Using air filtration to remove airborne SARS-CoV-2 and other microbial aerosols in COVID wards

University of Cambridge researchers conducted a study in two repurposed COVID-19 units in Addenbrooke’s Hospital, Cambridge, UK, between January and February 2021. During this time, the alpha variant (lineage B1.1.7) accounted for >80% of the circulating SARS-CoV-2. This study, posted to the medRxiv* preprint server, aimed to provide evidence of the removal of SARS-CoV-2 and microbial bioaerosols using portable air filters with UV sterilization.

24 Sep 2021

Mathematical constructions of SARS-CoV-2 action could help fine-tune prevention and treatment

Mathematical constructions of the action of SARS-CoV-2 and its multiple spikes, which enable its success at infecting cells, can give vaccine developers and pharmaceutical companies alike a more precise picture of what the virus is doing inside us and help fine tune prevention and treatment, mathematical modelers say.

23 Sep 2021

Potential covalent SARS-CoV-2 spike protein inhibitors

There remains a significant need for new and effective drugs that can be used to treat COVID-19.

23 Sep 2021

How SARS-CoV-2 spike binds to multiple host receptors

Researchers from the Genos Glycoscience Research Laboratory in Croatia have recently investigated the sites that the S protein is capable of binding with.

23 Sep 2021

COVID-19 vaccination and lactation

A new study evaluates the presence of antibodies in breastmilk and the immune responses of lactating women after vaccination of the COVID-19 vaccine.

23 Sep 2021

Design of mRNA vaccines to combat COVID-19

A recent review study discusses fundamental concepts in the successful delivery of nucleic acids in therapeutics.

23 Sep 2021

COVID-19 vaccination eases healthcare demand

A new study discusses a model that has been developed to predict the effects of relaxing restrictions on the number of new COVID-19 cases.

23 Sep 2021

COVID-19 transmission is higher with warm weather and increased visits to indoors public places, study finds

A new study finds that environmental factors and human mobility predict seasonal changes in COVID-19 rates, just as in influenza and similar diseases.

23 Sep 2021

New methodology for evaluating transmissibility and competitive advantages of co-circulating SARS-CoV-2 variants

A new study examines how SARS-CoV-2 variants confer a competitive advantage on the virus, fueling further transmission and mortality.

23 Sep 2021

Altered characteristics of granulocytes in COVID-19 patients can be linked to disease severity

COVID-19 disease severity seems to be affected by the characteristics of white blood cells called granulocytes, which are part of the innate immune system.

23 Sep 2021

People with natural immunity and subsequent mRNA vaccination can neutralize viral particles capable of resisting vaccine-induced antibodies

New research suggests SARS-CoV-2 spike protein substitution mutations can create a replication-defective viral particle that makes the virus resistant to vaccine-induced antibodies.

23 Sep 2021

Varying immune responses after single dose of Pfizer and AstraZeneca COVID-19 vaccines

A new preprint describes the significant variation in the early immune response elicited by two of the earliest vaccines to gain emergency authorization against COVID-19.

23 Sep 2021

Differences in blood gene expression among patients with varying COVID-19 severity

A new study published on the medRxiv* pre-print server and currently undergoing peer-review aims to answer this question through whole blood transcriptomics of individuals with varying degrees of COVID-19 severity. Transcriptomics, done by RNA sequencing, gives insights into the genes expressed in a cell at a given time point. It gives an analysis of all RNA molecules within a cell, in this case, whole blood.

23 Sep 2021

Long-term effects of COVID-19 in children

A recent preprint deals with the incidence and importance of long COVID in children.

23 Sep 2021

The impact of multiple sclerosis therapy on COVID-19 vaccine efficacy

In a paper, the vaccine-induced cellular and immune response of MS patients receiving a range of therapies are assessed.

23 Sep 2021

SARS News and Research

No excess mortality during the Delta variant era in US state with high vaccination rates

A daily pill to treat covid could be just months away, scientists say

Research shows ozone as a potential disinfectant agent in public transport

Human milk antibodies elicited by vaccination show reduced activity against SARS-CoV-2 VoCs

Effect of prior SARS-CoV-2 infection on post-vaccination SARS-CoV-2 spike IgG antibodies

Using air filtration to remove airborne SARS-CoV-2 and other microbial aerosols in COVID wards

Mathematical constructions of SARS-CoV-2 action could help fine-tune prevention and treatment

Potential covalent SARS-CoV-2 spike protein inhibitors

How SARS-CoV-2 spike binds to multiple host receptors

COVID-19 vaccination and lactation

Design of mRNA vaccines to combat COVID-19

COVID-19 vaccination eases healthcare demand

COVID-19 transmission is higher with warm weather and increased visits to indoors public places, study finds

New methodology for evaluating transmissibility and competitive advantages of co-circulating SARS-CoV-2 variants

Altered characteristics of granulocytes in COVID-19 patients can be linked to disease severity

People with natural immunity and subsequent mRNA vaccination can neutralize viral particles capable of resisting vaccine-induced antibodies

Varying immune responses after single dose of Pfizer and AstraZeneca COVID-19 vaccines

Differences in blood gene expression among patients with varying COVID-19 severity

Long-term effects of COVID-19 in children

The impact of multiple sclerosis therapy on COVID-19 vaccine efficacy

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