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Targeted 'click-to-release' chemotherapy leads to potent antitumor activity in mice

Antibody Drug Conjugates are relatively new anti-cancer drugs. They consist of an antibody to which a cell-killing molecule (chemotherapy) is attached. Antibodies can recognize and bind to certain receptors (the 'hands' on the outside of a cell) in a very targeted way.

4 May 2018

Cancer Center at BIDMC announces launch of new Immunotherapy Institute

The Cancer Center at Beth Israel Deaconess Medical Center today announced the launch of a new clinical and research institute that will build on BIDMC's long history of leadership in immunotherapy and cell therapeutics.

3 May 2018

Penn surgeons perform first ever robot-assisted complex spinal surgery for rare tumor removal

Noah Pernikoff is back to his life in New York City after becoming the first patient in the world to undergo a complex three-part, robotic-assisted surgery.

3 May 2018

New study evaluates expression of PD-L1 in human medulloblastoma

This study evaluated the expression of PD-L1 and markers of immune mediated resistance in human medulloblastoma, the most common malignant pediatric brain tumor.

3 May 2018

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

One major hallmark of cancer cells is their ability to adapt to stressful conditions such as nutrient deprivation. Rapidly growing tumor cells must compete for the ever-diminishing supply of nutrients in the surrounding environment to survive and proliferate. Targeting these adaptive mechanisms represents a promising approach for cancer therapeutics.

3 May 2018

Study finds no connection between weekday for lung cancer operation and patient survival

The day of the week on which a patient has a lung cancer operation has no significance for their survival. This has been demonstrated by researchers at Karolinska Institutet in a new study published in the journal Chest.

3 May 2018

Nearly 50 people present with rare eye cancer - ocular melanoma

At least 50 people have been diagnosed with a rare type of eye cancer called ocular melanoma. They are all residents of two locations - Huntersville, North Carolina, and Auburn, Alabama. The cancer is rare and occurs in only six per 1 million population. The high rate of incidence of this cancer in these two locations has stumped researchers.

2 May 2018

Researchers develop novel theranostic procedure for treating ductal pancreatic adenocarcinoma

German researchers have developed a novel diagnostic and therapeutic (theranostic) procedure for patients with ductal pancreatic adenocarcinoma, a deadly cancer with an extremely poor prognosis (five-year survival rate of less than 5 percent) and limited treatment options. The study is featured in the May issue of The Journal of Nuclear Medicine.

2 May 2018

Lymph node status after preoperative therapy determines survival of esophageal cancer patients

According to a new study, the status of lymph nodes rather than the status of the primary tumor following preoperative neoadjuvant chemotherapy or chemoradiation therapy is the most important factor that determines whether patients with locally advanced esophageal cancer will survive.

2 May 2018

As proton centers struggle, a sign of a health care bubble?

The Maryland Proton Treatment Center chose "Survivor" as the theme for its grand opening in 2016, invoking the reality-TV show's tropical sets with its own Tiki torches, palm trees and thatched booths piled with pineapples and bananas.

2 May 2018

Researchers discover substance that could lead to cheaper and smaller MRI machines

Researchers at the National High Magnetic Field Laboratory have discovered a substance that could help MRI machines evolve from today’s bulky behemoths to hand-held scanners straight out of “Star Trek.”

2 May 2018

Non-aspirin NSAID use linked to shorter survival in patients with metastatic renal cell carcinoma

Ibuprofen, aspirin, and other non-steroidal anti-inflammatory medications are among the most commonly utilized medications in the United States. Primarily for treating pain, inflammation, and preventing cardiovascular disease, NSAIDs' promising anti-cancer properties have been highlighted by a growing body of data in recent years.

2 May 2018

New vaccine strategy increases number of tumor-specific cancer-killing T cells

New research published in Cancer Immunology Research by Drs. Esteban Celis and Hussein Sultan of the Georgia Cancer Center at Augusta University could serve as the stepping-stone in constructing vaccines with a greater likelihood of finding and attacking tumors in the human body.

2 May 2018

Direct contact with lymphatic endothelial cells promotes melanoma metastasis

Despite the declining death rates for many individual cancer types, mortality for a few cancers has stabilized or even increased. One of these is melanoma due to its ability, in later stages, to spread to other parts of the body.

2 May 2018

New T cell biomarker could be much-needed patient-selection tool for CAR T cell therapy

Penn Medicine researchers may have found the reason why some patients with advanced chronic lymphocytic leukemia don't respond to chimeric antigen receptor T cell therapy, and the answer is tied to how primed patients' immune systems are before the therapy is administered.

30 Apr 2018

Auditory brainstem implant helps patients with neurofibromatosis type 2

Patients with rare brain tumors on the auditory nerve now have an option to prevent complete deafness at UC San Diego Health. The device, called an auditory brainstem implant or ABI, fits behind the ear and connects directly to the brainstem.

30 Apr 2018

New pill for breast cancer diagnosis could do a better job than mammograms

As many as one in three women treated for breast cancer undergo unnecessary procedures, but a new method for diagnosing it could do a better job distinguishing between benign and aggressive tumors.

30 Apr 2018

Researchers show how Spred1 molecule protects HSC homeostasis under diet-induced stress

Researchers at Kanazawa University report in Cell Stem Cell how the Spred1 molecule is involved in hematopoietic stem cell self-renewal. Experiments with mouse models show that under normal conditions, Spred1 acts as a negative regulator, while under diet-induced stress, it protects hematopoietic homeostasis.

28 Apr 2018

New results reinforce COPAXONE 40 mg/mL as safe and effective for RMS patients

Teva Pharmaceutical Industries Ltd., today announced up to 7-year efficacy, safety and tolerability results from the Glatiramer Acetate Low-Frequency Administration (GALA) open-label extension study of COPAXONE (glatiramer acetate injection) 40 mg/mL administered subcutaneously three-times-a-week for the treatment of relapsing forms of multiple sclerosis (RMS).

28 Apr 2018

Pioneering study could be a step closer to finding the most effective way to treat cancer

Doctors could be a step closer to finding the most effective way to treat cancer with a double whammy of a virus combined with boosting the natural immune system, according to a pioneering study by researchers at The University of Texas Health Science Center at Houston (UTHealth) and The Ohio State University.

27 Apr 2018

Tumor News and Research

Targeted 'click-to-release' chemotherapy leads to potent antitumor activity in mice

Cancer Center at BIDMC announces launch of new Immunotherapy Institute

Penn surgeons perform first ever robot-assisted complex spinal surgery for rare tumor removal

New study evaluates expression of PD-L1 in human medulloblastoma

Study provides vital information to develop successful PI5P4K inhibitors for p53-mutant cancers

Study finds no connection between weekday for lung cancer operation and patient survival

Nearly 50 people present with rare eye cancer - ocular melanoma

Researchers develop novel theranostic procedure for treating ductal pancreatic adenocarcinoma

Lymph node status after preoperative therapy determines survival of esophageal cancer patients

As proton centers struggle, a sign of a health care bubble?

Researchers discover substance that could lead to cheaper and smaller MRI machines

Non-aspirin NSAID use linked to shorter survival in patients with metastatic renal cell carcinoma

New vaccine strategy increases number of tumor-specific cancer-killing T cells

Direct contact with lymphatic endothelial cells promotes melanoma metastasis

New T cell biomarker could be much-needed patient-selection tool for CAR T cell therapy

Auditory brainstem implant helps patients with neurofibromatosis type 2

New pill for breast cancer diagnosis could do a better job than mammograms

Researchers show how Spred1 molecule protects HSC homeostasis under diet-induced stress

New results reinforce COPAXONE 40 mg/mL as safe and effective for RMS patients

Pioneering study could be a step closer to finding the most effective way to treat cancer

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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