Disease Modeling News and Research

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Novel respiratory model predicts mechanisms altered by SARS-CoV-2 variants

Researchers study cell infection and viral replication methods affected by SARS-CoV-2 mutations through a novel respiratory model.

28 Feb 2022

Harvard’s new kidney engineering technology licensed to San Diego-based Trestle Biotherapeutics

A newly launched startup is building upon innovations developed over several years at the Wyss Institute for Biologically Inspired Engineering at Harvard University, Harvard John A. Paulson School of Engineering & Applied Sciences (SEAS), and Brigham and Women’s Hospital (Brigham) to engineer functional kidney tissue for renal repair and replacement therapy.

25 Feb 2022

Exploring the relationship between stem cells and COVID-19

Though COVID-19-related stem cell clinical research is still in its infancy, stem cell treatment offers extensive clinical application possibilities and a far-reaching relevance thanks to ongoing exploration of stem cell clinical research and data mining.

14 Jan 2022

UC researchers to examine how stress hormones affect cell degeneration in Parkinson's patients

Stress can have a negative effect on anyone's health but presents particular challenges for people with Parkinson's disease.

13 Jan 2022

NAU bioengineer receives grant to improve the accuracy, fidelity of cardiovascular flow models

Accurately measuring blood flow is critical to the fundamental understanding of cardiovascular disease and clinical decision making. Although researchers have made great strides in computational and experimental blood flow modeling, reliable data is still difficult to generate in large quantities.

12 Jan 2022

Lab engineered human A549 lung cell model conducive for investigating SARS-CoV-2 antivirals

Researchers developed a human A549 lung epithelial cell-based model to probe SARS-CoV-2 replication.

9 Jan 2022

Microgravity likely to contribute to life-saving stem cell advances on Earth

The secret to producing large batches of stem cells more efficiently may lie in the near-zero gravity conditions of space. Scientists at Cedars-Sinai have found that microgravity has the potential to contribute to life-saving advances on Earth by facilitating the rapid mass production of stem cells.

30 Dec 2021

Mapping access to HIV care

In this interview, we speak to Professor Diego Cuadros about his latest research in which he mapped individuals' access to HIV care in Africa.

23 Dec 2021

Engineering of brain-mimetic injectable hydrogel scaffolds with self-healing properties

A team of scientists bioengineered a physiologically relevant, brain mimetic 3D scaffold for culturing neuronal cells.

15 Dec 2021

Improving access to health care is key to reducing HIV incidence

Many patients living with HIV in rural Africa are not receiving regular treatment, despite recent efforts to increase access to health care across the continent.

30 Nov 2021

Stem cell treatment reduced deaths related to cardiovascular issues, not hospitalization

Stem cell therapy helped to reduce the number of heart attacks, strokes and death among people with chronic, high-risk, NYHA class II or III heart failure with reduced ejection fraction (HFrEF), especially among those who have higher levels of inflammation, yet hospitalization was not reduced, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2021.

15 Nov 2021

CDC announces $26 million to develop next-generation infectious disease forecasting and analytics

The Centers for Disease Control and Prevention (CDC) today announced $26 Million in funding to develop next-generation infectious disease forecasting and analytics.

30 Oct 2021

More strategic COVID-19 testing can reduce reliance on costly preventative interventions

Strategically increasing testing capacity, either by making diagnostic tests faster or more available, can reduce reliance on costly preventative interventions, such as distancing and shutdowns, according to a team of researchers led by Penn State.

28 Oct 2021

New guidelines to standardize reporting of epidemic prediction research

An international panel has designed new guidelines to standardize how scientists report research that involves forecasting and prediction of how epidemics of infectious diseases unfold. Simon Pollett of the Walter Reed Army Institute of Research in Maryland, United States, and colleagues present the guidelines, called EPIFORGE, in the open-access journal PLOS Medicine on October 19th.

20 Oct 2021

Second most common malaria parasite causes unrecognized burden on global health

The malaria parasite Plasmodium vivax (P. vivax) causes frequent, chronic infections that represent a major unrecognized burden on global health, according to a review by Kevin Baird of the Eijkman-Oxford Clinical Research Unit in Indonesia and Katherine Battle of the Institute for Disease Modeling in the United States publishing October 7th in the open access journal PLOS Medicine.

8 Oct 2021

Early implementation of social distancing policies results in smaller death tolls, but larger second waves

Early social distancing results in smaller death tolls, but leads to larger second waves, according to research led by faculty at Binghamton University, State University of New York.

8 Sep 2021

Researchers develop adult lung organoids that represent all cell types

Since the COVID-19 pandemic reached the United States in early 2020, scientists have struggled to find laboratory models of SARS-CoV-2 infection, the respiratory virus that causes COVID-19. Animal models fell short; attempts to grow adult human lungs have historically failed because not all of the cell types survived.

31 Aug 2021

New discovery may lead to more effective treatments for osteoarthritis, other cartilage diseases

New information from a study reported on in STEM CELLS might result in more effective treatments for osteoarthritis and other cartilage diseases, as well as hereditary disorders affecting cartilage development.

25 Aug 2021

Researchers recommend urgent adaptation plans to mitigate heat-related deaths and illnesses

Extreme heat is an increasingly common occurrence worldwide, with heat-related deaths and illnesses also expected to rise.

20 Aug 2021

New bioengineered lung model could help scientists to advance research in lung conditions

An interdisciplinary team of researchers from McMaster and SickKids are developing a cutting-edge lung model that can better respond to viruses and drug treatments, giving scientists a tool to advance research in lung conditions like COVID-19, cystic fibrosis and allergens for asthma and air pollution.

18 Aug 2021